ChemicalBook > CAS DataBase List > IODIPAMIDE

IODIPAMIDE

Product Name
IODIPAMIDE
CAS No.
606-17-7
Chemical Name
IODIPAMIDE
Synonyms
adipiodon;bilignost;IODIPAMIDE;ADIPIODONE;biligrafin;cholospect;transbilix;cholografin;iodipamicacid;Iodipamide (200 mg)
CBNumber
CB3125304
Molecular Formula
C20H14I6N2O6
Formula Weight
1139.76
MOL File
606-17-7.mol
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IODIPAMIDE Property

Melting point:
306-308°C (dec.)
Boiling point:
908.6±65.0 °C(Predicted)
Density 
2.5848 (estimate)
refractive index 
nD21.5 1.3294 (c = 0.445 in methanol)
storage temp. 
Room Temperature
solubility 
DMSO (Slightly), Methanol (Very Slightly)
pka
pKa 3.5(H2O) (Uncertain)
form 
Solid
color 
White
Water Solubility 
0.46g/L(20 ºC)
Merck 
5022
EPA Substance Registry System
Benzoic acid, 3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodo- (606-17-7)
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Safety

WGK Germany 
3
RTECS 
DG0949500
HS Code 
2924296000
Hazardous Substances Data
606-17-7(Hazardous Substances Data)
Toxicity
LD50 in mice, rats (mg/kg): 2380 ±290, 4430 ±310 i.v. (Rosenberg)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1343007
Product name
Iodipamide
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$358
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR3188
Product name
Iodipamide
Purity
pharmaceutical secondary standard, certified reference material
Packaging
500MG
Price
$162
Updated
2022/05/15
Sigma-Aldrich
Product number
I0639
Product name
Iodipamide
Purity
analytical standard, for drug analysis
Packaging
5g
Price
$72.9
Updated
2022/05/15
TRC
Product number
I666800
Product name
Iodipamide
Packaging
5mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FI24595
Product name
Iodipamide
Packaging
25mg
Price
$130
Updated
2021/12/16
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IODIPAMIDE Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Originator

Cholografin,Squibb,US,1954

Uses

Diagnostic aid (radiopaque medium-cholecystographic).

Uses

antihypertensive, diuretic, activates K channels and AMPA receptors

Definition

ChEBI: Adipiodone is an organoiodine compound that is 3-amino-2,4,6-triiodobenzoic acid in which one of the amino hydrogens is substituted by a 6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl group. It is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography. It has a role as a radioopaque medium. It is an organoiodine compound, a member of benzoic acids and a secondary carboxamide. It is a conjugate acid of an adipiodone(2-).

Manufacturing Process

125 g of 2,4,6-triiodo-3-amino benzoic acid are dissolved in 250 cc of chlorobenzene and 15 g of adipic acid dichloride are added at a temperature between 110° and 130°C drop by drop to the solution. After evolution of hydrochloric acid (about 2 to 3 hours) has ceased, the precipitated crude adipic acid di-(3-carboxy-2,4,6-triiodo anilide) of the above formula is filtered hot with suction, washed with chlorobenzene, extracted by boiling with methanol and, for purification, dissolved in an amount of methanolic caustic soda solution required for neutralization, filtered with charcoal, and precipitated with dilute hydrochloric acid. Yield: 82.3 g, MP 306° to 308°C (with decomposition).

brand name

Pharmaceutic necessity for Iodipamide Meglumine [Injection]. Cholografin (Bristol-Myers Squibb).

Therapeutic Function

Diagnostic aid (radiopaque medium)

Hazard

Toxic by ingestion.

IODIPAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from IODIPAMIDE manufacturers

Career Henan Chemical Co
Product
3,3-Adipoyldiiminobis(2,4,6-Triiodobenzoic Acid) 606-17-7
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

606-17-7, IODIPAMIDERelated Search:


  • 3,3’-(adipoyldiimino)bis(2,4,6-triiodo-benzoicaci
  • adipiodon
  • 3,3(ADIPOYLDIIMINO)BIS(2,4,6-TRIIODOBENZOIC ACID)
  • 3,3'-ADIPOYLDIIMINOBIS(2,4,6-TRIIODOBENZOIC ACID)
  • 2,2,4,4,6,6-hexaiodo-3,3-adipoyldiiminodi(benzoic acid)
  • 3,3'-[(1,6-Dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodobenzoic Acid
  • Adipic Acid Bis(3-carboxy-2,4,6-triiodoanilide)
  • 3-[[6-(3-carboxy-2,4,6-triiodo-anilino)-6-keto-hexanoyl]amino]-2,4,6-triiodo-benzoic acid
  • 3-[[6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
  • 3-[[6-[(3-carboxy-2,4,6-triiodo-phenyl)amino]-6-oxo-hexanoyl]amino]-2,4,6-triiodo-benzoic acid
  • Iodipamide (200 mg)
  • IodipaMide SynonyMs 3,3'(AdipoyldiiMino)-bis[2,4,6-triiodobenzoic acid]
  • Adipic acid di(3-carboxy-2,4,6-triiodoanilide)
  • IODIPAMIDE
  • LABOTEST-BB LT00772037
  • ADIPIODONE
  • bilignost
  • biligrafin
  • cholografin
  • cholospect
  • iodipamicacid
  • transbilix
  • Iodipamide (Adipiodone)
  • Iodipamide (Synonyms: Adipiodone)
  • Benzoic acid, 3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodo-
  • IODIPAMIDE USP/EP/BP
  • Iodipamide,Inhibitor,inhibit
  • Iodipamide, ≥ 98.0%
  • Iodipamide in methanol
  • Iodipamide, 10 mM in DMSO
  • 606-17-7
  • C20H14I6N2O6
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