Sodium chlorodifluoroacetate

Product Name: Sodium chlorodifluoroacetate
CAS No.: 1895-39-2
Chemical Name: Sodium chlorodifluoroacetate
Synonyms: Sodium 2-chloro-2,2-difluoroacetate;2-chloro-2,2-difluoroacetate;SodiuM Difluorochloroacetate;CHLORODIFLUOROACETIC ACID SODIUM SALT;DIFLUOROCHLOROACETIC ACID SODIUM SALT;orodifL;Sodiumchlorodifluoride;Sodiumdifluorochlorate;Roflumilast impurity 24;SODIUM CHLORODIFLUOROACETATE
CBNumber: CB3135211
Molecular Formula: C2HClF2O2.Na
Formula Weight: 153.47
MOL File: 1895-39-2.mol

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Sodium chlorodifluoroacetate Property

Melting point:: 196-198 °C (lit.)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Soluble in dimethoxyethane, diglyme (0.60 g mL-1), triglyme, dimethyl formamide.
form: Powder
color: White to off-white
BRN: 4162363
InChI: InChI=1S/C2HClF2O2.Na.H/c3-2(4,5)1(6)7;;/h(H,6,7);;
InChIKey: MRTAVLDNYYEJHK-UHFFFAOYSA-M
SMILES: C(F)(F)(Cl)C(=O)O.[NaH]
CAS DataBase Reference: 1895-39-2(CAS DataBase Reference)
EPA Substance Registry System: Acetic acid, chlorodifluoro-, sodium salt (1895-39-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-24/25-36/37/39
WGK Germany: 3
Hazard Note: Irritant
TSCA: T
HazardClass: IRRITANT, HYGROSCOPIC
HS Code: 29159080

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 374067
Product name: Sodium chlorodifluoroacetate
Purity: 96%
Packaging: 25g
Price: $90.8
Updated: 2025/07/31

TCI Chemical

Product number: C0991
Product name: Sodium Chlorodifluoroacetate
Purity: >99.0%(T)
Packaging: 25g
Price: $29
Updated: 2025/07/31

TCI Chemical

Product number: C0991
Product name: Sodium Chlorodifluoroacetate
Purity: >99.0%(T)
Packaging: 100g
Price: $82
Updated: 2025/07/31

TCI Chemical

Product number: C0991
Product name: Sodium Chlorodifluoroacetate
Purity: >99.0%(T)
Packaging: 500g
Price: $267
Updated: 2025/07/31

Usbiological

Product number: 289074
Product name: Sodium chlorodifluoroacetate
Packaging: 50g
Price: $333
Updated: 2021/12/16

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Sodium chlorodifluoroacetate Chemical Properties,Usage,Production

Chemical Properties

white to off-white powder

Uses

It is used as pharmaceutical intermediate. Reactions of aldehydes with triphenylphosphine and sodium chlorodifluoroacetate yield 1,1-difluoro olefins. It is a general reaction and a one step synthesis.

Application

Sodium chlorodifluoroacetate is used for generation of difluorocarbene and the synthesis of difluorocyclopropanes and difluoroalkenes.

Preparation

Sodium chlorodifluoroacetate is prepared by careful neutralization of 130.5 g (1.0 mol) of chlorodifluoroacetic acid in 300 mL of Et2O with 53 g (0.5 mol) of anhydrous Na2CO3. The Et2O and water are removed under reduced pressure. The salt is then dried in a vacuum desiccator over P2O5. ^[1]

storage

Sodium chlorodifluoroacetate is an irritant and is hygroscopic.

References

1. Herkes, F. E.; Burton, D. J. OSC 1973, 5, 949

Sodium chlorodifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Sodium chlorodifluoroacetate Suppliers

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View Lastest Price from Sodium chlorodifluoroacetate manufacturers

Hangzhou Verychem Science And Technology Co.Ltd

Product: Sodium chlorodifluoroacetate 1895-39-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100 tons
Release date: 2025-12-01

Hebei Chuanghai Biotechnology Co., Ltd

Product: Sodium chlorodifluoroacetate 1895-39-2
Price: US $9.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-26

Henan Aochuang Chemical Co.,Ltd.

Product: Sodium chlorodifluoroacetate 1895-39-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-09

1895-39-2, Sodium chlorodifluoroacetateRelated Search:

Dichloroacetyl chloride Sodium bicarbonate Sodium chlorite Sodium fluorosilicate Trisodium hexafluoroaluminate Sodium chloroacetate Sodium chloride Sodium hydroxide Sodium citrate Sodium benzoate Diclofenac sodium Sodium acetate Chlorodifluoroacetic acid Trisodium phosphate Difluoroacetic acid 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Ethyl bromodifluoroacetate METHYL DIFLUOROACETATE

DIFLUOROCHLOROACETIC ACID SODIUM SALT

CHLORODIFLUOROACETIC ACID, NA

CHLORODIFLUOROACETIC ACID SODIUM

CHLORODIFLUOROACETIC ACID SODIUM SALT

chlorodifluoro-aceticacisodiumsalt

SODIUM CHLORODIFLUOROACETATE

Sodium chlorodifluoroacetate 97%

Sodiumchlorodifluoroacetate97%

Acetic acid, chlorodifluoro-, sodium salt

Sodium 2-chloro-2,2-difluoroacetate

Chlorodifluoroacetic acid sodium salt,96%

Chlorodifluoroacetic acid sodium salt 5g [1895-39-2]

Sodium chlorodifluoroacetate,Chlorodifluoroacetic acid sodium salt

Chlorodifluoroacetic acid sodiuM salt, 96% 25GR

2-Chloro-2,2-difluoro-acetic Acid SodiuM Salt

SodiuM Difluorochloroacetate

Sodium 2-chloro-2,2-difluoroethanoate, Chloro(difluoro)acetic acid, sodium salt

Two fluorinesodiuM chloroacetate

Acetic acid,2-chloro-2,2-difluoro-, sodiuM salt (1:1)

orodifL

Roflumilast impurity 24

Sodium Chlorodifluoroacetate &gt

2-chloro-2,2-difluoroacetate

Sodiumchlorodifluoride

Sodiumdifluorochlorate

1895-39-2

1985-39-2

C2ClFNaO2

ClCF2CO2Na

C2ClF2NaO2

C2ClF2O2Na

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