Betaxolol hydrochloride
- Product Name
- Betaxolol hydrochloride
- CAS No.
- 63659-19-8
- Chemical Name
- Betaxolol hydrochloride
- Synonyms
- Kerlon;kerlone;SL 75212;betoptic;sl-d.212;Betaxolo;Betoptima;sl75212-10;SL 75212 HCl;Betaxolol HC
- CBNumber
- CB3153329
- Molecular Formula
- C18H30ClNO3
- Formula Weight
- 343.89
- MOL File
- 63659-19-8.mol
Betaxolol hydrochloride Property
- Melting point:
- 116°
- storage temp.
- 2-8°C
- solubility
- H2O: 36 mg/mL, soluble
- form
- solid
- color
- white
- Water Solubility
- Soluble to 50 mM in water
- Merck
- 14,1182
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
- InChIKey
- CHDPSNLJFOQTRK-UHFFFAOYSA-N
- SMILES
- C1(OCC(O)CNC(C)C)C=CC(CCOCC2CC2)=CC=1.Cl
- CAS DataBase Reference
- 63659-19-8(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- Y0001360
- Product name
- Betaxolol for peak identification
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 15 mg
- Price
- $118
- Updated
- 2025/07/31
- Product number
- B5683
- Product name
- Betaxolol hydrochloride
- Purity
- >98% (HPLC)
- Packaging
- 10mg
- Price
- $137.2
- Updated
- 2025/07/31
- Product number
- BP686
- Product name
- Betaxolol hydrochloride
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100 mg
- Price
- $234
- Updated
- 2025/07/31
- Product number
- B1103000
- Product name
- Betaxolol hydrochloride
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 60 mg
- Price
- $153
- Updated
- 2025/07/31
- Product number
- 1069903
- Product name
- Betaxolol hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $425
- Updated
- 2025/07/31
Betaxolol hydrochloride Chemical Properties,Usage,Production
Description
Betaxolol (hydrochloride) (Item No. 26285) is an analytical reference standard categorized as a β1-adrenergic receptor antagonist. Formulations containing β-adrenergic receptor antagonists have been used to enhance physical performance in athletes. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .
Description
Betaxolol hydrochloride is a cardioselective β-adrenergic blocker, reportedly devoid of intrinsic sympathomimetic and membrane stabilizing properties. Its long duration of action permits once-daily dosing in mild to moderate hypertension. It is also being evaluated in glaucoma.
Chemical Properties
White or almost white, crystalline powder.
Originator
Synthelabo (France)
Uses
antifungal
Uses
Betaxolol Hydrochloride, a cardioselective β1-adrenergic blocker. An antihypertensive; antiglaucoma.
Definition
ChEBI: The hydrochloride salt of betaxolol.
brand name
Betoptic (Alcon); Kerlone (Sanofi Aventis).
Biological Activity
Selective β 1 -adrenoceptor antagonist.
storage
Store at RT
References
[1] SEUNG-WOON MYUNG Cheon H J. Gas chromatograph–mass spectrometric method for the determination of carvedilol and its metabolites in human urine[J]. Journal of Chromatography B, 2005, 822 1: Pages 70-77. DOI: 10.1016/j.jchromb.2005.05.023
[2] PANKAJ GUPTA R G. Amino Functionalized Graphene Oxide and Polymer Nanocomposite Based Electrochemical Platform for Sensitive Assay of Anti-Doping Drug Atenolol in Biological Fluids[J]. Journal of The Electrochemical Society, 2016, 163 1. DOI: 10.1149/2.0281613jes
[3] A WELLSTEIN G G B D Palm. Affinity and selectivity of beta-adrenoceptor antagonists in vitro.[J]. Journal of Cardiovascular Pharmacology, 1986, 8 Suppl 11: S36-40. DOI: 10.1097/00005344-198511001-00006
[4] DOROTA POZAROWSKA Zbigniew D Piotr Pozarowski. Cytometric assessment of cytostatic and cytotoxic effects of topical glaucoma medications on human epithelial corneal line cells?[J]. Cytometry Part B: Clinical Cytometry, 2009, 78B 2: 130-137. DOI: 10.1002/cyto.b.20493
[5] N. SHARIF. Levobetaxolol (Betaxon) and other beta-adrenergic antagonists: preclinical pharmacology, IOP-lowering activity and sites of action in human eyes.[J]. Journal of Ocular Pharmacology and Therapeutics, 2001, 26 1: 305-317. DOI: 10.1089/108076801753162726
[6] GLYN CHIDLOW Neville N O José Melena. Betaxolol, a β1-adrenoceptor antagonist, reduces Na+ influx into cortical synaptosomes by direct interaction with Na+ channels: comparison with other β-adrenoceptor antagonists[J]. British Journal of Pharmacology, 2009, 130 4: 759-766. DOI: 10.1038/sj.bjp.0703369
Betaxolol hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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- Country
- Switzerland
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View Lastest Price from Betaxolol hydrochloride manufacturers
- Product
- Betaxolol hydrochloride 63659-19-8
- Price
- US $0.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 500KGS
- Release date
- 2021-09-13
- Product
- Betaxolo hydrochloride 63659-19-8
- Price
- US $1.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2024-08-20
- Product
- Betaxolol hydrochloride 63659-19-8
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-11-17