ChemicalBook > CAS DataBase List > BIOTIN HYDRAZIDE
BIOTIN HYDRAZIDE
- Product Name
- BIOTIN HYDRAZIDE
- CAS No.
- 66640-86-6
- Chemical Name
- BIOTIN HYDRAZIDE
- Synonyms
- Biotin-Hz;Biotin-NHNH2;CAS_66640-86-6;5-((3aS,4S,6aR);BIOTIN-Hydrazid;BIOTIN-HYDRAZIDE;BIOTIN HYDRAZIDE;Biontin-Hydrazide;Biotin Impurity 32;Biotinyl hydrazine
- CBNumber
- CB3175354
- Molecular Formula
- C10H18N4O2S
- Formula Weight
- 258.34
- MOL File
- 66640-86-6.mol
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BIOTIN HYDRAZIDE Property
- Melting point:
- 245-247 °C
- Boiling point:
- 633.1±40.0 °C(Predicted)
- Density
- 1.243±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≤20 mg/mL
- form
- powder
- pka
- 13.25±0.35(Predicted)
- color
- White to Almost white
- BRN
- 28347
- InChIKey
- KOZWHQPRAOJMBN-ZKWXMUAHSA-N
- CAS DataBase Reference
- 66640-86-6(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- B7639
- Product name
- (+)-Biotin hydrazide
- Purity
- ≥97% (TLC), powder
- Packaging
- 100mg
- Price
- $102
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- B7639
- Product name
- (+)-Biotin hydrazide
- Purity
- ≥97% (TLC), powder
- Packaging
- 1g
- Price
- $520
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B2431
- Product name
- Biotin Hydrazide
- Purity
- >98.0%(HPLC)
- Packaging
- 25mg
- Price
- $32
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B2431
- Product name
- Biotin Hydrazide
- Purity
- >98.0%(HPLC)
- Packaging
- 100mg
- Price
- $89
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18418
- Product name
- Biotin hydrazide
- Purity
- ≥95%
- Packaging
- 100mg
- Price
- $57
- Updated
- 2024/03/01
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BIOTIN HYDRAZIDE Chemical Properties,Usage,Production
Description
Biotin hydrazide is a biotinyl derivative used to label surface functional groups, antibodies, lectins, sugars, nucleic acids, or molecules with free carboxylic or keto groups. Biotin hydrazide is used as a probe for determining protein carbonylation, an irreversible posttranslational modification resulting from the actions of reactive oxygen species or lipid oxidation products. The reaction of this probe is direct and does not require catalysts or reducing agents.
Chemical Properties
3.6
Uses
Biotin Hydrazide is a carbohydrate reactive biotinylation reagent used predominately for labeling monoclonal antibodies, unpaired cytosine residues in nucleic acids and glycoproteins.
Uses
aldehyde reactive biotinylation reagent
Uses
(+)-Biotin hydrazide has been used:
- the modification of alginate
- for the labelling of mitochondrial proteins from non-muscle tissues
- as a component of glycoprotein staining solution
- in periodic acid-biotin-hydrazide (PABH) assay for mucins
- for labeling surface functional groups, biologically active molecules such as antibodies, lectins, sugars, nucleic acids or molecules with free carboxylic or keto groups.
- for coupling to glycoproteins through the carbohydrate by hydrazone formation
General Description
Biotin hydrazide is a biotinylation reagent used to biotinylate glycoproteins with their sugar moieties. Biotin hydrazide can be used to prepare biotin-conjugated alginate. It can also be used for covalent attachment to PAAc via carbodi-imide cross linking.
Purification Methods
Wash the hydrazide with H2O, dry it, wash it with MeOH then Et2O, and dry. Recrystallise it from hot H2O (clusters of prisms) [Hofmann et al. J Biol Chem 144 513 1942]. [Beilstein 27 III/IV 7980.]
BIOTIN HYDRAZIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BIOTIN HYDRAZIDE manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Biotin hydrazide HCl 66640-86-6
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >95.00%
- Supply Ability
- 5g
- Release date
- 2024-03-30
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- BIOTIN HYDRAZIDE 66640-86-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- BIOTIN HYDRAZIDE 66640-86-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08
66640-86-6, BIOTIN HYDRAZIDERelated Search:
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DANSYL HYDRAZINE
Sulfo-NHS-Biotin
biotinylamidoethylacetamide
N-BIOTINYL-N'-MALEIMIDO-ETHYLENEDIAMINE
BIOTIN-XX-NHS
D-BIOTIN P-NITROPHENYL ESTER
D-Biotin
(+)-BIOTIN-EPSILON-AMINOCAPROIC ACID
Succinimidyl 6-(biotinamido)hexanoate
BIOTIN-NHS
Biotin-PEG6-t-butyl ester
Biotin-PEG3-alcohol
DBCO-S-S-PEG3-Biotin
Biotin-PEG2-iodide
1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(2-hydroxyethoxy)ethyl]-2-oxo-, (3aS,4S,6aR)-
Biotin-PEG6-azide
Biotin-PEG4-Amide-C6-Azide