ChemicalBook > CAS DataBase List > 3-Bromo-5-fluorobenzonitrile

3-Bromo-5-fluorobenzonitrile

Product Name
3-Bromo-5-fluorobenzonitrile
CAS No.
179898-34-1
Chemical Name
3-Bromo-5-fluorobenzonitrile
Synonyms
3-BROMO-5-FLUOROBENZONITRILE;3-Cyano-5-fluorobromobenzene;3-BroMo-5-fluoronitrobenzene;3-Bromo-5-fluorobenzonitrole;Benzonitrile, 3-bromo-5-fluoro-;3-Bromo-5-fluorobenzonitrile98%;3-Bromo-5-fluorobenzonitrile 98%;-Bromo-5-fluorobenzonitrile 98%
CBNumber
CB3184567
Molecular Formula
C7H3BrFN
Formula Weight
200.01
MOL File
179898-34-1.mol
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3-Bromo-5-fluorobenzonitrile Property

Melting point:
43 °C
Boiling point:
218.7±20.0 °C(Predicted)
Density 
1.69±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to lump
color 
White to Almost white
CAS DataBase Reference
179898-34-1(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xi,Xn
Risk Statements 
20/21/22-36/37/38-36-22
Safety Statements 
26-36/37/39
RIDADR 
3439
Hazard Note 
Toxic
HazardClass 
6.1
PackingGroup 
III
HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS003867
Product name
3-Bromo-5-fluorobenzonitrile
Purity
AldrichCPR
Packaging
250mg
Price
$61.6
Updated
2023/06/20
TCI Chemical
Product number
B4600
Product name
3-Bromo-5-fluorobenzonitrile
Purity
>98.0%(GC)
Packaging
1g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
B4600
Product name
3-Bromo-5-fluorobenzonitrile
Purity
>98.0%(GC)
Packaging
5g
Price
$63
Updated
2024/03/01
Alfa Aesar
Product number
H26066
Product name
3-Bromo-5-fluorobenzonitrile, 98%
Packaging
1g
Price
$20.65
Updated
2024/03/01
Alfa Aesar
Product number
H26066
Product name
3-Bromo-5-fluorobenzonitrile, 98%
Packaging
10g
Price
$130.65
Updated
2024/03/01
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3-Bromo-5-fluorobenzonitrile Chemical Properties,Usage,Production

Chemical Properties

off-white crystalline

Uses

3-Bromo-5-fluorobenzonitrile is a compound of benzonitrile containing bromine and fluorine atoms, which is mainly used as an intermediate component in organic synthesis.

Synthesis

3-Bromo-5-fluorobenzonitrile is synthesised using 1,3-dibromo-5-fluorobenzene as a raw material by chemical reaction. The specific synthesis steps are as follows:
A 250-mL round-bottom flask equipped with a magnetic stir bar was charged with 1,3-dibromo-5-fluorobenzene (7.70 g, 30.3 mmol), DMF (45 mL), pyridine (4.9 mL), and copper (I) cyanide (2.72 g, 30.3 mmol) under nitrogen. A reflux condenser was attached to the flask. The green, cloudy mixture was stirred at reflux for 3 h. Once lower Rf impurities were observed, the reaction was allowed to cool to room temperature. The reaction was quenched with 30 mL of ether, and a precipitate formed in the dark solution. The precipitate was gravity-filtered though Celite. The filtrate was rinsed three times with ether (100 mL/50 g bromide). The isolated solution was added to a separatory funnel. The organic layer was washed with a 2:1 mixture of water and concentrated ammonium hydroxide (30 mL), followed by saturated ammonium chloride solution (2*30 mL) and saturated sodium bicarbonate (30 mL). The aqueous layers were extracted with ether (3*40 mL). The organic layers were combined and dried over anhydrous sodium sulfate. The product was purified by flash column chomatography to yield 3-bromo-5-fluorobenzonitrile (2.10 g, 35percent). 1H NMR (400 MHz, CDCl3) δ 7.62 (s, 1H), 7.54-7.50 (m, 1H), 7.35-7.32 (m, 1H).

3-Bromo-5-fluorobenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Bromo-5-fluorobenzonitrile Suppliers

Americas 1 Canada 1 China 163 Europe 3 Germany 2 India 7 Italy 1 Japan 1 United Kingdom 17 United States 36 Global 232
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View Lastest Price from 3-Bromo-5-fluorobenzonitrile manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
3-Bromo-5-fluorobenzonitrile 179898-34-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-19
Hebei Mujin Biotechnology Co.,Ltd
Product
3-Bromo-5-fluorobenzonitrile 179898-34-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-27
Career Henan Chemical Co
Product
3-Bromo-5-fluorobenzonitrile 179898-34-1
Price
US $8.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-15

179898-34-1, 3-Bromo-5-fluorobenzonitrileRelated Search:

Florfenicol DBDCB 4-Fluorobenzonitrile 1,3-Difluorobenzene Chlorfenapyr Transfluthrin 4-Bromofluorobenzene 3-BROMO-2-FLUOROBENZONITRILE 96% 5-bromo-3-fluorobenzonitrile 4-BROMO-3-FLUOROBENZONITRILE,4-Bromo-3-fluorobenzonitrile97% 4-BROMO-2-FLUOROBENZONITRILE,4-Bromo-2-fluorobenzonitrile 98%,4-Bromo-2-fluorobenzonitrile98%,4-BROMO-2-FLUOROBENZONITRILE 99+% 3-BROMO-4-FLUOROBENZONITRILE,3-Bromo-4-fluorobenzonitrile 98%,3-Bromo-4-fluorobenzonitrile98% 2-Bromo-4-fluorobenzonitrile 98%,2-Bromo-4-fluorobenzonitrile98%,2-BROMO-4-FLUOROBENZONITRILE Bromine 2-Bromo-5-fluorobenzonitrile, 98+%,2-Bromo-5-fluorobenzonitrile 99%,2-BROMO-5-FLUOROBENZONITRILE,2-Bromo-5-fluorobenzonitrile99% 2,3,4-Trifluorotoluene 4-Amino-3-bromo-5-fluorobenzonitrile 5-BROMO-2-FLUOROBENZONITRILE,5-Bromo-2-fluorobenzonitrile 98%,5-Bromo-2-fluorobenzonitrile98%

  • -Bromo-5-fluorobenzonitrile 98%
  • 3-BroMo-5-fluoronitrobenzene
  • 3-Cyano-5-fluorobromobenzene
  • 3-BROMO-5-FLUOROBENZONITRILE
  • 3-Bromo-5-fluorobenzonitrile 98%
  • 3-Bromo-5-fluorobenzonitrile98%
  • 3-Bromo-5-fluorobenzonitrole
  • Benzonitrile, 3-bromo-5-fluoro-
  • 179898-34-1
  • 17898-34-1
  • C7H3BrN
  • Fluorobenzene
  • Fluorine series
  • Aromatic Nitriles
  • Nitrile
  • Miscellaneous
  • Bromine Compounds
  • Fluorine Compounds
  • Nitriles
  • Multisubstituted Benzene