5-Fluoro-2-hydroxypyridine

Product Name: 5-Fluoro-2-hydroxypyridine
CAS No.: 51173-05-8
Chemical Name: 5-Fluoro-2-hydroxypyridine
Synonyms: 5-Fluoropyridin-2-ol;5-Fluorpyridin-2-ol;5-Fluoro-2-pyridinol;uoro-2-hydroxypyridine;5-fluoro-1H-pyridin-2-one;5-Fluoropyridin-2(1H)-one;3-Fluoro-6-hydroxypyridine;5-FLUORO-2-HYDROXYPYRIDINE;2-HYDROXY-5-FLUOROPYRIDINE;2(1H)-Pyridinone, 5-fluoro-
CBNumber: CB3203611
Molecular Formula: C5H4FNO
Formula Weight: 113.09
MOL File: 51173-05-8.mol

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5-Fluoro-2-hydroxypyridine Property

Melting point:: 150-155°C
Boiling point:: 251.7±40.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 10.09±0.10(Predicted)
form: Crystalline Powder
color: White to off-white
InChIKey: KLULSYPVWLJZAO-UHFFFAOYSA-N
CAS DataBase Reference: 51173-05-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 753181
Product name: 5-Fluoro-2-hydroxypyridine
Purity: 97%
Packaging: 1g
Price: $46.5
Updated: 2023/06/20

TRC

Product number: F597988
Product name: 5-Fluoro-2-hydroxypyridine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 035690
Product name: 5-Fluoro-2-hydroxypyridine
Purity: 95+%
Packaging: 5g
Price: $59
Updated: 2021/12/16

BroadPharm

Product number: BP-11523
Product name: 5-fluoropyridin-2-olhydrobromide
Packaging: 5G
Price: $185
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 35270
Product name: 5-Fluoro-2-hydroxypyridine
Purity: 98%
Packaging: 10g
Price: $445
Updated: 2021/12/16

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5-Fluoro-2-hydroxypyridine Chemical Properties,Usage,Production

Uses

5-Fluoro-2-hydroxypyridine is a halogenated compound used in the synthesis of 5-Fluoro-2-hydroxy-3-nitropyridine and 5-halogenated pyrimidine compounds.

Synthesis

5-Fluoro-2-hydroxypyridine is synthesised using 5-fluoro-2-methoxypyridine as a raw material by chemical reaction. The specific synthesis steps are as follows:
A total of 4.6 L of toluene solution containing 3-80 was placed in several sealed tubes and treated with 900 ml of 35percent HCl at 145° C. for 2 hr. LC/MS showed no starting material, only 4. The toluene solution was decanted and discarded. The aqueous phase was washed with EtOAc and concentrated down to remove volatiles to afford a brown solid containing the desired fluoro-hydroxypyridine 4-80. [1488] A total of 244 g of this solid was collected and taken to next step as is (it was not completely dry). [1489] Note: We have subsequently run this by decanting the toluene layer first prior to heating to reduce volumes. Same reaction was carried out using HBr (48percent in H2O) at 100° C. for 6 h with similar result to the literature procedure 49percent yield. [1490] Ref: J. Heterocyclic Chem., 10, 779, 1973 (for above Reactions, Including Analytical Data).

5-Fluoro-2-hydroxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Fluoro-2-hydroxypyridine Suppliers

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View Lastest Price from 5-Fluoro-2-hydroxypyridine manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 5-Fluoro-2-hydroxypyridine 51173-05-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2023-04-12

Henan Fengda Chemical Co., Ltd

Product: 5-Fluoro-2-hydroxypyridine 51173-05-8
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

Hebei Mojin Biotechnology Co., Ltd

Product: 5-Fluoro-2-hydroxypyridine 51173-05-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000tons
Release date: 2023-08-07

51173-05-8, 5-Fluoro-2-hydroxypyridineRelated Search:

Sulfasalazine Chrysin Chromium picolinate Hydroxy silicone oil 2-Chloro-3-cyanopyridine 2-Hydroxypyridine 3-BROMO-5-FLUORO-2-METHOXYPYRIDINE 2,6-Dihydroxy-5-fluoro-3-cyanopyridine 5-FLUORO-2-METHOXYPYRIDINE-4-BORONIC ACID 5-FLUORO-2-HYDROXY-3-NITROPYRIDINE 4-BROMO-5-FLUORO-2-HYDROXY-3-NITROPYRIDINE 5-Fluoro-2-methoxynicotinic acid 5-Fluoro-2-methoxy-3-methylpyridine 2-Methoxy-5-fluoropyridine Fluorine 5-FLUORO-2-HYDROXYNICOTINIC ACID 5-FLUORO-2-METHOXY-6-PICOLINE 4-Pyridinecarboxaldehyde, 5-fluoro-1,2-dihydro-2-oxo- (9CI)

2-HYDROXY-5-FLUOROPYRIDINE

5-FLUORO-2-HYDROXYPYRIDINE

3-Fluoro-6-hydroxypyridine

5-Fluoropyridin-2-ol

5-Fluoropyridin-2(1H)-one

5- fluoro-2-hydroxyl pyridine

5-Fluoro-2-pyridinol

uoro-2-hydroxypyridine

2(1H)-Pyridinone, 5-fluoro-

5-Fluoro-2-hydroxypyridine ISO 9001：2015 REACH

5-fluoro-1H-pyridin-2-one

5-Fluorpyridin-2-ol

51173-05-8

C5H4NOF

Fluorine series

blocks

FluoroCompounds

Pyridines

Pyridine

Fluorin-contained pyridine series