ChemicalBook > CAS DataBase List > Tetradecylthioacetic acid

Tetradecylthioacetic acid

Product Name
Tetradecylthioacetic acid
CAS No.
2921-20-2
Chemical Name
Tetradecylthioacetic acid
Synonyms
TTA;Tetradecylthio Acid;hexadecanethioic S-acid;TetradecylthioaceticAci;Tetradcylthioacetic Acid;Tetradecyl thioglycolato;TETRADECYLTHIOACETIC ACID;2-(myristylthio)acetic acid;2-(Tetradecylthio)acetic Acid;THTRADECYLMERCAPTO ACETIC ACID
CBNumber
CB3211423
Molecular Formula
C16H32O2S
Formula Weight
288.49
MOL File
2921-20-2.mol
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Tetradecylthioacetic acid Property

Melting point:
65-73°C
Boiling point:
402.6±28.0 °C(Predicted)
Density 
0.957±0.06 g/cm3(Predicted)
RTECS 
AJ5087000
storage temp. 
-20°C Freezer
solubility 
DMSO: ≥22 mg/mL, soluble
pka
3.85±0.10(Predicted)
form 
Solid
color 
white
CAS DataBase Reference
2921-20-2(CAS DataBase Reference)
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Safety

WGK Germany 
3
HS Code 
2930.90.9250
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T1698
Product name
Tetradecylthioacetic acid
Purity
≥97% (NMR)
Packaging
5mg
Price
$85.8
Updated
2022/05/15
TCI Chemical
Product number
T3787
Product name
2-(Tetradecylthio)acetic Acid
Packaging
1G
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
T3787
Product name
2-(Tetradecylthio)acetic Acid
Packaging
5G
Price
$114
Updated
2024/03/01
Alfa Aesar
Product number
J67350
Product name
Tetradecylthioacetic acid
Purity
98%
Packaging
10mg
Price
$155.4
Updated
2023/01/06
Usbiological
Product number
T2967-01
Product name
Tetradecylthioacetic Acid
Packaging
50mg
Price
$425
Updated
2021/12/16
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Tetradecylthioacetic acid Chemical Properties,Usage,Production

Description

Tetradecylthioacetic acid (TTA), a representative member of the 3-thia family, has the chemical structure of palmitic acid (C16) in which a sulfur atom is located between the 2 and 3-carbon atoms (COOH-CH2-S-(CH2)13-CH3). TTA is a novel hypolipidemic drug which has been shown to combine several effects of w-3 PUFAs, such as EPA, and structurally unrelated peroxisome proliferators, such as phenylacetate and fibrates. From this perspective we wanted to investigate if TTA shares the antitumor activity found for these functionally related compounds, and furthermore to study the metabolic effects of TTA in cancer cells in relation to the effects found in hepatocytes.

Chemical Properties

White Cyrstalline Solid

Uses

TTA is a novel thio-fatty acid which cannot undergo beta-oxidation. It induces apoptosis in IPC-81 leukemia cells via depolarization of mitochondrial membrane potential and inhibits glioma cell proliferation. TTA completely prevents high fat diet-induced insulin resistance and adiposity in Wistar rats. Activates rodent PPAR’s with rank order PPARα>PPARδ>PPARγ.

Definition

ChEBI: 2-(tetradecylthio)acetic acid is a straight-chain fatty acid.

Tetradecylthioacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tetradecylthioacetic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Tetradecylthioacetic Acid 2921-20-2
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-22
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Tetradecylthioacetic Acid 2921-20-2
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-19
Hebei Mojin Biotechnology Co.,Ltd
Product
Tetradecylthioacetic acid 2921-20-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-06-13

2921-20-2, Tetradecylthioacetic acidRelated Search:


  • TETRADECYLTHIOACETIC ACID
  • TETRADECYLMERCAPTO ACETIC ACID
  • THTRADECYLMERCAPTO ACETIC ACID
  • Tetradcylthioacetic Acid
  • 1-(carboxymethylthio)tetradecane
  • 1-MONO(CARBOXYMETHYLTHIO)TETRADECANE
  • TTA
  • Tetradecylthioacetic acid (TTA)
  • 2-(myristylthio)acetic acid
  • 2-tetradecylsulfanylacetic acid
  • 2-tetradecylsulfanylethanoic acid
  • 2-(Tetradecylthio)acetic Acid
  • Acetic acid,2-(tetradecylthio)-
  • Tetradecyl thioglycolato
  • hexadecanethioic S-acid
  • Tetradecylthio Acid
  • TetradecylthioaceticAci
  • discount Tetradecylthioacetic acid
  • Peroxisome proliferator-activated receptors,β-Oxidation,inhibit,fatty acid oxidation,Inhibitor,PPAR,Tetradecylthioacetic acid,2-(Tetradecylthio)acetic acid,hypolipidemia
  • 2921-20-2
  • C16H32O2S
  • C16H32SO2
  • C14H29SCH2COOH
  • PPAR and RXR Regulators
  • Gene Regulation and Expression
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Apoptosis
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Inhibitors
  • Sulfur & Selenium Compounds