ChemicalBook > CAS DataBase List > 4-Hydroxybenzyl alcohol

4-Hydroxybenzyl alcohol

Product Name
4-Hydroxybenzyl alcohol
CAS No.
623-05-2
Chemical Name
4-Hydroxybenzyl alcohol
Synonyms
4-(Hydroxymethyl)phenol;P-HYDROXYBENZYL ALCOHOL;Gastrodigenin;p-Hydroxybenzyl;p-Methylolphenol;4-hydroxyphenyl Methanol;P-hydroxylbenzyl alcohol;Benzenemethanol, 4-hydroxy-;FEMA 3987;ω-Hydroxycresol
CBNumber
CB3224331
Molecular Formula
C7H8O2
Formula Weight
124.14
MOL File
623-05-2.mol
More
Less

4-Hydroxybenzyl alcohol Property

Melting point:
114-122 °C(lit.)
Boiling point:
251-253°C
Density 
1.1006 (rough estimate)
refractive index 
1.5035 (estimate)
FEMA 
3987 | 4-HYDROXYBENZYL ALCOHOL
Flash point:
251-253°C
storage temp. 
Store below +30°C.
solubility 
6.7g/l soluble
pka
pK1:9.82 (25°C)
form 
Crystalline Powder
color 
Pink to beige
Odor
at 100.00 %. fruity bitter almond sweet coconut
Odor Type
fruity
biological source
synthetic
Water Solubility 
Soluble in water (6.7 mg/ml at 20°C), dioxane (100 mg/ml), 1N NaOH (50 mg/ml), DMSO, and methanol.
Sensitive 
Light Sensitive/Air Sensitive
JECFA Number
955
BRN 
1858967
InChIKey
BVJSUAQZOZWCKN-UHFFFAOYSA-N
LogP
0.21
CAS DataBase Reference
623-05-2(CAS DataBase Reference)
NIST Chemistry Reference
Benzenemethanol, 4-hydroxy-(623-05-2)
EPA Substance Registry System
4-Hydroxybenzenemethanol (623-05-2)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36-36/37/38
Safety Statements 
26-24/25-36
WGK Germany 
3
RTECS 
DA4796800
F 
8-9-23
Hazard Note 
Irritant/Keep Cold/Air Sensitive/Light Sensitive
HS Code 
29072900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W398705
Product name
4-Hydroxybenzyl alcohol
Purity
≥98%, FG
Packaging
1 unit
Price
$56.3
Updated
2025/07/31
Sigma-Aldrich
Product number
W398705
Product name
4-Hydroxybenzyl alcohol
Purity
≥98%, FG
Packaging
1 unit
Price
$56.3
Updated
2025/07/31
Sigma-Aldrich
Product number
H20806
Product name
4-Hydroxybenzyl alcohol
Purity
99%
Packaging
10g
Price
$60.7
Updated
2025/07/31
TCI Chemical
Product number
H0224
Product name
4-Hydroxybenzyl Alcohol
Purity
>97.0%(GC)
Packaging
25g
Price
$30
Updated
2025/07/31
TCI Chemical
Product number
H0224
Product name
4-Hydroxybenzyl Alcohol
Purity
>97.0%(GC)
Packaging
100g
Price
$115
Updated
2025/07/31
More
Less

4-Hydroxybenzyl alcohol Chemical Properties,Usage,Production

Chemical Properties

Pink to beige crystalline powder

Chemical Properties

4-Hydroxybenzyl alcohol is a white crystalline powder with slightly fruity-sweet coconut odor

Occurrence

Reportedly found in vanilla, Bourbon (Vanilla plantifolia Andrew

Uses

4-Hydroxybenzyl alcohol is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Preparation

Prepared from p-cresol by using the microorganism, Pseudomonas putida.

Definition

ChEBI: P-hydroxybenzyl alcohol is a member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung. It has a role as a plant metabolite. It is a member of phenols and a member of benzyl alcohols.

General Description

4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is as an antioxidant and anti-asthmatic agent.

Flammability and Explosibility

Not classified

reaction suitability

reagent type: cross-linking reagent

Contact allergens

Methylol phenols are sensitizers contained in resins based on phenol and formaldehyde of the resol type. Cross-reactivity is possible with other phenol derivative molecules.

IC 50

IC50 >0.2 mM (human); ALDH5A1: IC50 >1 mM (human); ABAT: IC50 >1 mM (human); Tyrosinase: IC50 >1 mM (Agaricus bisporus)

Purification Methods

Crystallise the alcohol from H2O, *C6H6 (m 124o), *C6H6/EtOH or ClCH2CH2Cl (m 122o). [Beilstein 6 III 4546, 6 IV 5909.]

4-Hydroxybenzyl alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Hydroxybenzyl alcohol Suppliers

Americas 1 Belgium 1 Canada 1 China 609 Czech Republic 1 Europe 3 France 2 Germany 10 India 97 Japan 8 Poland 1 Russia 1 Slovakia 1 South Korea 2 Spain 1 Switzerland 4 Ukraine 1 United Kingdom 17 United States 64 USA 1 Global 826
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
Alfa Chemistry
Tel
+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Synovel Laboratory LLC
Tel
--
Fax
--
Email
sales@synovellab.com
Country
United States
ProdList
50
Advantage
58
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Pennbio Chemicals (U.S.A.)
Tel
--
Fax
--
Country
United States
ProdList
240
Advantage
58
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Prodasynth
Tel
--
Fax
--
Email
info@prodasynth.com
Country
United States
ProdList
423
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Molcan Corporation
Tel
--
Fax
--
Email
info@molcan.com
Country
United States
ProdList
686
Advantage
60
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Beijing Lys Chemicals Co, LTD.
Tel
--
Fax
--
Email
jiayanyong@lyschem.com
Country
United States
ProdList
710
Advantage
58
WholeChem, LLC
Tel
--
Fax
--
Email
info@wholechem.com
Country
United States
ProdList
814
Advantage
58
Penta International Corporation
Tel
--
Fax
--
Email
lisaa@pentamfg.com
Country
United States
ProdList
5042
Advantage
58
Ernesto Ventós S.A.
Tel
--
Fax
--
Email
info@ventos.com
Country
United States
ProdList
2257
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Rintech, Inc.
Tel
--
Fax
--
Email
info@rintechinc.com
Country
United States
ProdList
3416
Advantage
60
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
Penta Manufacturing Company
Tel
--
Fax
--
Email
sales@pentamfg.com
Country
United States
ProdList
5076
Advantage
65
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
More
Less

View Lastest Price from 4-Hydroxybenzyl alcohol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Hydroxybenzyl alcohol 623-05-2
Price
US $0.00-0.00/Kg/Drum
Min. Order
5KG
Purity
99%min
Supply Ability
15tons/month
Release date
2021-06-07
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Hydroxybenzyl alcohol 623-05-2
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-22
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
4-Hydroxybenzyl Alcohol 623-05-2
Price
US $100.00-45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-06

623-05-2, 4-Hydroxybenzyl alcoholRelated Search:

4-Hydroxy-D-(-)-2-phenylglycine Benzyl alcohol Triphenylmethanol 3,5-Dihydroxybenzyl alcohol Benzhydrol Ethyl acetate Ethylparaben 4-Cyanobenzoic acid 4-Methoxyphenol 4-Hydroxybenzoic acid 4-Hydroxybenzaldehyde 3-(4-Hydroxyphenyl)propionic acid Methyl 4-hydroxyphenylacetate Bisoprolol Impurity 17 Bisoprolol Impurity 11 Bisoprolol Impurity 16 Acetamide, N-[2-hydroxy-3-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]propyl]-N-(1-methylethyl)- 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenol hydrochloride

  • 4-hydroxyphenyl Methanol
  • 4-(Hydroxymethyl)phenol 98%
  • 4-Hydroxybenzyl alcohol, (4-Hydroxyphenyl)methanol
  • 4-Hydroxybenzyl alcohol, 97% 25GR
  • The hydroxy benzyl alcohol
  • P-(HYDROXYMETHYL)PHENOL
  • P-HYDROXYBENZYL ALCOHOL
  • RARECHEM AL BD 0098
  • P-hydroxylbenzyl alcohol
  • 4-Hydroxbenzyl alcohol
  • (4-hydroxybenzyl)ether
  • 4-METHYLOLPHENOL
  • 4-HYDROXYBENZYL ALCOHOL
  • 4-hydroxybenzenemethanol
  • HYDROXYBENZYL-4 ALCOHOL
  • FEMA 3987
  • 4-(Hydroxymethyl)phenol
  • alpha-Hydroxy-p-cresol
  • Benzyl alcohol, p-hydroxy-
  • Gastrodigenin
  • p-Methylolphenol
  • p-Hydroxy Benzyl Alcohol 4-Hydroxy Benzyl Alcohol
  • 4-HYDROXYBENZYL ALCOHOL 98+%
  • 4-HydroxybenzylAlcohol99%
  • PARA-HYDROXYBENZOYLALCOHOL
  • PARA-ALCOHOLPHENOL
  • 4-HYDROXYBENZYL ALCOHOL 99%
  • p-Hydroxybenzenemethanol
  • ω-Hydroxycresol
  • 4-Hydroxybenzyl alcohol,97%
  • p-Hydroxybenzyl
  • Benzenemethanol, 4-hydroxy-
  • 4-Hydroxybenzylic Alcohol
  • Bisoprolol Impurity 19
  • α,4‐Dihydroxytoluene
  • 4 Hydroxy benzyl alcohol (CAS No: 623-05-2)
  • Bisoprolol Alcohol Impurity (Gastrodigenin)
  • 4-Hydroxybenzyl Alcohol &gt
  • 4-HYDROXYBENZYL ALCOHOL FOR SYNTHESIS
  • Bisoprolol Impurity 13 (Gastrodigenin)
  • Para Hydroxylbenzyl alcohol
  • Bisoprolol Impurity 33
  • Bisoprolol Alcohol ImpurityQ: What is Bisoprolol Alcohol Impurity Q: What is the CAS Number of Bisoprolol Alcohol Impurity Q: What is the storage condition of Bisoprolol Alcohol Impurity Q: What are the applications of Bisoprolol Alcohol Impurity
  • 4-(Hydroxymethyl)phenol (BPL-I)
  • 4-Hydroxy Benzyl Alcohol pure, 98%
  • 4-HYDROXY BENZYLALCHOHOL
  • PARA HYDROXY BENZYL ALCOHOL
  • 4-Hydroxybenzyl alcohol, p-Hydroxybenzyl alcohol, 4-(Hydroxymethyl)phenol, Gastrodigenin, p-Hydroxybenzyl, p-Methylolphenol, 4-hydroxyphenyl Methanol, p-hydroxylbenzyl alcohol, Benzenemethanol, 4-hydroxy-, FEMA 3987, ω-Hydroxycresol
  • 4-Hydroxybenzyl alcohol, 10 mM in DMSO
  • 4-Hydroxybenzyl alcohol - [H4685]
  • 623-05-2
  • 0623-05-02
  • Alcohols
  • Building Blocks
  • C7 to C8
  • Organic Building Blocks
  • Oxygen Compounds
  • Aromatics