ChemicalBook > CAS DataBase List > 2-AMINO-5-BROMO-3-CHLOROPYRAZINE

2-AMINO-5-BROMO-3-CHLOROPYRAZINE

Product Name: 2-AMINO-5-BROMO-3-CHLOROPYRAZINE
CAS No.: 21943-13-5
Chemical Name: 2-AMINO-5-BROMO-3-CHLOROPYRAZINE
Synonyms: 5-broMo-3-chloropyrazin-2-aMine;2-Amino-5-bromo-3-chlorop...;5-Bromo-3-chloro-2-pyrazinamine;2-Amino-3-chloro-5-bromopyrazine;2-AMINO-5-BROMO-3-CHLOROPYRAZINE;2-Pyrazinamine, 5-bromo-3-chloro-;5-Bromo-3-chloro-pyrazin-2-ylamine;2-AMINO-5-BROMO-3-CHLOROPYRAZINE ISO 9001：2015 REACH
CBNumber: CB32455966
Molecular Formula: C4H3BrClN3
Formula Weight: 208.44
MOL File: 21943-13-5.mol

Less

2-AMINO-5-BROMO-3-CHLOROPYRAZINE Property

Melting point:: 128℃
Boiling point:: 271℃
Density: 1.960
Flash point:: 118℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 0.81±0.10(Predicted)
Appearance: Off-white to yellow Solid
InChI: InChI=1S/C4H3BrClN3/c5-2-1-8-4(7)3(6)9-2/h1H,(H2,7,8)
InChIKey: RLBJPMURTWCBMZ-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Br)N=C1Cl

Less

Safety

Risk Statements: 41
Safety Statements: 26-39
RIDADR: UN2811
HS Code: 2933998090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

Less

N-Bromosuccinimide Price

TRC

Product number: B699828
Product name: 5-Bromo-3-chloropyrazin-2-amine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 068665
Product name: 2-Amino-5-bromo-3-chloropyrazine
Purity: 95+%
Packaging: 1g
Price: $15
Updated: 2021/12/16

Matrix Scientific

Product number: 068665
Product name: 2-Amino-5-bromo-3-chloropyrazine
Purity: 95+%
Packaging: 5g
Price: $39
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140421
Product name: 5-Bromo-3-chloropyrazin-2-amine
Packaging: 100mg
Price: $40
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140421
Product name: 5-Bromo-3-chloropyrazin-2-amine
Packaging: 250mg
Price: $75
Updated: 2021/12/16

Less

2-AMINO-5-BROMO-3-CHLOROPYRAZINE Chemical Properties,Usage,Production

Synthesis

6863-73-6

21943-13-5

General procedure for the synthesis of 5-bromo-3-chloropyrazin-2-amine from 2-amino-3-chloropyrazine: a suspension of N-bromosuccinimide (NBS, 31.0 g, 173 mmol) and 2-amino-3-chloropyrazine (20.0 g, 154 mmol) in chloroform (140 mL) was heated and refluxed for 16 hours. Upon completion of the reaction, the solution was cooled to room temperature and washed with deionized water (350 mL). The organic layer was filtered through diatomaceous earth and subsequently concentrated under reduced pressure to give 5-bromo-3-chloropyrazin-2-amine (22.0 g, 69% yield) as a brown solid. The melting point of the product was 230-232 °C; the IR spectrum (thin film method, cm^-1 ) showed 3412 (NH2 stretching vibration), 3019 (aromatic C-H stretching vibration); the NMR hydrogen spectrum (500 MHz, CDCl3) δ 5.02 (2H, broad single peak, NH2), 8.05 (1H, single peak, 6-H); the NMR carbon spectrum (125 MHz , CDCl3) δ 123.5, 132.0, 142.9, 150.6; gas chromatography-mass spectrometry (GC-MS) showed m/z 211, 209, 207 (M+); gas chromatography retention time (tR) was 2.82 min; purity was >99%; high-resolution mass spectrometry (HRMS) measured value: m/z 207.9280 for MH+; calculated value: 207.9272.

References

[1] Tetrahedron, 2012, vol. 68, # 47, p. 9713 - 9728,16
[2] Tetrahedron, 2012, vol. 68, # 47, p. 9713 - 9728
[3] Patent: US2009/239847, 2009, A1. Location in patent: Page/Page column 46-47

2-AMINO-5-BROMO-3-CHLOROPYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-AMINO-5-BROMO-3-CHLOROPYRAZINE Suppliers

China 100 India 1 Switzerland 1 United Kingdom 3 United States 11 Global 116

Shanghai YuYuan Pharmaceutical Co., Ltd.

Tel: 13052276172
Fax: 13052276172
Email: product@yuyuanpharm.com
Country: China
ProdList: 493
Advantage: 55

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Suzhou Guide Fine Material Co.Ltd.

Tel: 0512-66627360 13914021065
Fax: 0512-66627360
Email: 706938434@qq.com
Country: China
ProdList: 237
Advantage: 60

Shanghai ZaiQi Bio-Tech Co., Ltd.

Tel: 021-54824098, 021-37212705 021-37212706, 13391256916
Fax: 021-54824069
Email: sales@chemzq.com
Country: China
ProdList: 570
Advantage: 55

Kohn & Shawn Pharmatech Co.,Ltd

Tel: 0931-4190454 13893344397
Fax: +86-931-8506154
Email: sales@kyxpharma.com
Country: China
ProdList: 310
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Aloespharm Co., Ltd.

Tel: 021-20960837
Fax: 021-20960837
Email: market@aloespharm.com
Country: China
ProdList: 1302
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chemfun Medical Technology(Shanghai) Co., Ltd.

Tel: 021-67220633 021-54824098
Fax: +86-21-54824069
Email: chemfun@chemfun.net
Country: China
ProdList: 491
Advantage: 58

Nanjing YiFan Biological Technology Co., Ltd.

Tel: 025-025-52700520 18914499889
Fax: 025-52700520
Email: sales@yfbiotech.com
Country: China
ProdList: 495
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Nanjing Duolong Bio-tech Co.,Ltd.

Tel: 18905173768
Fax: 025-83263139
Email: 52513593@qq.com
Country: China
ProdList: 2331
Advantage: 50

Shanghai Jovan Biochemical Technology Co. Ltd.

Tel: +86-021-61654350
Fax: +86-021-61654350
Email: 1245958370@qq.com
Country: China
ProdList: 2982
Advantage: 50

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Bellen Chemistry Co., Ltd.

Tel: 010-60400365-8001 15910885229
Fax: 010-60400361
Email: service@bellenchem.com
Country: China
ProdList: 4514
Advantage: 60

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

skychemical Co.Ltd

Tel: 021-20960837,QQ1332204249
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 3341
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10110
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4967
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2815688 13927872512
Fax: 0751-8963795
Email: 3007421951@qq.com
Country: China
ProdList: 9939
Advantage: 58

wuhan Dekray Biomedical Technology Co.,Ltd

Tel: 027-69573188 18221423799
Email: 1503407886@qq.com
Country: China
ProdList: 1439
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Shanghai Chenghe Medical Technology Co. Ltd.

Tel: 021-021-54382182 18601603956
Email: 18601603956@163.com
Country: China
ProdList: 1255
Advantage: 58

Nanjing Asfam Pharmaceutical Technology Co., Ltd.

Tel: 025-58867862 18751812725
Fax: 02558867862
Email: sales@ace-pharm.com
Country: China
ProdList: 1985
Advantage: 58

Lanzhou Kangyuxin Biotechnology Co., Ltd.

Tel: 0931-4190454 13893344397
Email: sales@kyxpharma.com
Country: China
ProdList: 3153
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55055611 18137792234
Fax: QQ：3002694073
Email: 3002694073@qq.com
Country: China
ProdList: 9987
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

SIMAGCHEM CORP

Tel: +86-5922680277 +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17346
Advantage: 58

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: +86-0731-85567275 13298656710
Fax: QQ:3554193828
Email: sales05@chemfish.com
Country: China
ProdList: 7448
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Hebei Chuanghai Biotechnology Co., Ltd

Tel: +8615350571055
Fax: whatapp+8619930503282
Email: Sibel@chuanghaibio.com
Country: China
ProdList: 8768
Advantage: 58

Changzhou ruiqing medical technology co., LTD

Tel: 0519-85859396 15380475813
Email: 656870630@qq.com
Country: China
ProdList: 485
Advantage: 58

Less

View Lastest Price from 2-AMINO-5-BROMO-3-CHLOROPYRAZINE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Bromo-3-chloropyrazin-2-amine 21943-13-5
Price: US $1.60-6.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-AMINO-5-BROMO-3-CHLOROPYRAZINE 21943-13-5
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-11

Shaanxi Dideu Medichem Co. Ltd

Product: 5-Bromo-3-chloropyrazin-2-amine 21943-13-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-29

21943-13-5, 2-AMINO-5-BROMO-3-CHLOROPYRAZINERelated Search:

Ethyl 2-(ethoxymethylene)acetoacetate 3-Cyanocinnamic acid 2-(Bromomethyl)pyridine hydrobromide 2,6-Dichlorobenzoxazole 2H-1,4-BENZOXAZIN-3(4H)-ONE 3-Benzyloxy-1-propanol 2-Methyl-3-nitropyridine 2-Nitrodiphenylamine Curcuma oil 4-Fluorobenzenesulfonamide 2-Chloro-3-bromo-5-methylpyridine 4-BROMOISATIN 2,6-Difluorobenzenesulfonyl chloride 5-Nitropyridine-2-carboxylic acid 6-Azaindole-3-carboxaldehyde Sulfachoropyrazine sodium 2-AMINO-5-BROMO-3-CHLOROPYRAZINE 2-Bromo-6-chloropyrazine

2-AMINO-5-BROMO-3-CHLOROPYRAZINE

5-Bromo-3-chloro-pyrazin-2-ylamine

2-Amino-5-bromo-3-chlorop...

5-broMo-3-chloropyrazin-2-aMine

2-Amino-3-chloro-5-bromopyrazine

2-Pyrazinamine, 5-bromo-3-chloro-

2-AMINO-5-BROMO-3-CHLOROPYRAZINE ISO 9001：2015 REACH

5-Bromo-3-chloro-2-pyrazinamine

21943-13-5