2-AMINO-5-BROMO-3-CHLOROPYRAZINE

Product Name: 2-AMINO-5-BROMO-3-CHLOROPYRAZINE
CAS No.: 21943-13-5
Chemical Name: 2-AMINO-5-BROMO-3-CHLOROPYRAZINE
Synonyms: 5-broMo-3-chloropyrazin-2-aMine;2-Amino-5-bromo-3-chlorop...;5-Bromo-3-chloro-2-pyrazinamine;2-Amino-3-chloro-5-bromopyrazine;2-AMINO-5-BROMO-3-CHLOROPYRAZINE;2-Pyrazinamine, 5-bromo-3-chloro-;5-Bromo-3-chloro-pyrazin-2-ylamine;2-AMINO-5-BROMO-3-CHLOROPYRAZINE ISO 9001：2015 REACH
CBNumber: CB32455966
Molecular Formula: C4H3BrClN3
Formula Weight: 208.44
MOL File: 21943-13-5.mol

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2-AMINO-5-BROMO-3-CHLOROPYRAZINE Property

Melting point:: 128℃
Boiling point:: 271℃
Density: 1.960
Flash point:: 118℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 0.81±0.10(Predicted)
Appearance: Off-white to yellow Solid
InChI: InChI=1S/C4H3BrClN3/c5-2-1-8-4(7)3(6)9-2/h1H,(H2,7,8)
InChIKey: RLBJPMURTWCBMZ-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Br)N=C1Cl

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Safety

Risk Statements: 41
Safety Statements: 26-39
RIDADR: UN2811
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: B699828
Product name: 5-Bromo-3-chloropyrazin-2-amine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-D-16
Product name: 5-Bromo-3-chloropyrazin-2-amine
Packaging: 25g
Price: $580
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0143568
Product name: 2-AMINO-5-BROMO-3-CHLOROPYRAZINE
Purity: 95.00%
Packaging: 1G
Price: $796.95
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0143568
Product name: 2-AMINO-5-BROMO-3-CHLOROPYRAZINE
Purity: 95.00%
Packaging: 5G
Price: $1472.63
Updated: 2021/12/16

Matrix Scientific

Product number: 068665
Product name: 2-Amino-5-bromo-3-chloropyrazine
Purity: 95+%
Packaging: 1g
Price: $15
Updated: 2021/12/16

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2-AMINO-5-BROMO-3-CHLOROPYRAZINE Chemical Properties,Usage,Production

Synthesis

6863-73-6

21943-13-5

General procedure for the synthesis of 5-bromo-3-chloropyrazin-2-amine from 2-amino-3-chloropyrazine: a suspension of N-bromosuccinimide (NBS, 31.0 g, 173 mmol) and 2-amino-3-chloropyrazine (20.0 g, 154 mmol) in chloroform (140 mL) was heated and refluxed for 16 hours. Upon completion of the reaction, the solution was cooled to room temperature and washed with deionized water (350 mL). The organic layer was filtered through diatomaceous earth and subsequently concentrated under reduced pressure to give 5-bromo-3-chloropyrazin-2-amine (22.0 g, 69% yield) as a brown solid. The melting point of the product was 230-232 °C; the IR spectrum (thin film method, cm^-1 ) showed 3412 (NH2 stretching vibration), 3019 (aromatic C-H stretching vibration); the NMR hydrogen spectrum (500 MHz, CDCl3) δ 5.02 (2H, broad single peak, NH2), 8.05 (1H, single peak, 6-H); the NMR carbon spectrum (125 MHz , CDCl3) δ 123.5, 132.0, 142.9, 150.6; gas chromatography-mass spectrometry (GC-MS) showed m/z 211, 209, 207 (M+); gas chromatography retention time (tR) was 2.82 min; purity was >99%; high-resolution mass spectrometry (HRMS) measured value: m/z 207.9280 for MH+; calculated value: 207.9272.

References

[1] Tetrahedron, 2012, vol. 68, # 47, p. 9713 - 9728,16
[2] Tetrahedron, 2012, vol. 68, # 47, p. 9713 - 9728
[3] Patent: US2009/239847, 2009, A1. Location in patent: Page/Page column 46-47

2-AMINO-5-BROMO-3-CHLOROPYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-BROMO-3-CHLOROPYRAZINE Suppliers

China 100 India 1 Switzerland 1 United Kingdom 3 United States 11 Global 116

Shanghai YuYuan Pharmaceutical Co., Ltd.

Tel: 13052276172
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Email: product@yuyuanpharm.com
Country: China
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J & K SCIENTIFIC LTD.

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Pure Chemistry Scientific Inc.

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Shanghai Hanhong Scientific Co.,Ltd.

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Shanghai ZaiQi Bio-Tech Co., Ltd.

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Kohn & Shawn Pharmatech Co.,Ltd

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Shanghai Jian Chao Chemical Technology Co., Ltd.

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View Lastest Price from 2-AMINO-5-BROMO-3-CHLOROPYRAZINE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Bromo-3-chloropyrazin-2-amine 21943-13-5
Price: US $1.60-6.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-AMINO-5-BROMO-3-CHLOROPYRAZINE 21943-13-5
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-11

Shaanxi Dideu Medichem Co. Ltd

Product: 5-Bromo-3-chloropyrazin-2-amine 21943-13-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-29

21943-13-5, 2-AMINO-5-BROMO-3-CHLOROPYRAZINERelated Search:

Ethyl 2-(ethoxymethylene)acetoacetate 3-Cyanocinnamic acid 2-(Bromomethyl)pyridine hydrobromide 2,6-Dichlorobenzoxazole 2H-1,4-BENZOXAZIN-3(4H)-ONE 3-Benzyloxy-1-propanol 2-Methyl-3-nitropyridine 2-Nitrodiphenylamine Curcuma oil 4-Fluorobenzenesulfonamide 2-Chloro-3-bromo-5-methylpyridine 4-BROMOISATIN 2,6-Difluorobenzenesulfonyl chloride 5-Nitropyridine-2-carboxylic acid 6-Azaindole-3-carboxaldehyde Sulfachoropyrazine sodium 2-AMINO-5-BROMO-3-CHLOROPYRAZINE 2-Bromo-6-chloropyrazine

2-AMINO-5-BROMO-3-CHLOROPYRAZINE

5-Bromo-3-chloro-pyrazin-2-ylamine

2-Amino-5-bromo-3-chlorop...

5-broMo-3-chloropyrazin-2-aMine

2-Amino-3-chloro-5-bromopyrazine

2-Pyrazinamine, 5-bromo-3-chloro-

2-AMINO-5-BROMO-3-CHLOROPYRAZINE ISO 9001：2015 REACH

5-Bromo-3-chloro-2-pyrazinamine

21943-13-5