ChemicalBook > CAS DataBase List > Deoxyarbutin

Deoxyarbutin

Product Name
Deoxyarbutin
CAS No.
53936-56-4
Chemical Name
Deoxyarbutin
Synonyms
Tetrahydropyranyloxyphenol;Dexyarbutin;Deoxyarbutin;LGB-D ARBUTIN;Deoxyarbutin, 98%+;Deoxyarbutin 53936-56-4;Tranexamic acid 701-54-2;Pure Deoxyarbutin Powder;4-[(2-Tetrahydropyranyl)oxy]phenol;4-(TETRAHYDRO-2H-2-PYRANYLOXY)PHENOL
CBNumber
CB32473685
Molecular Formula
C11H14O3
Formula Weight
194.23
MOL File
53936-56-4.mol
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Deoxyarbutin Property

Melting point:
88-89 °C(Solv: ligroine (8032-32-4))
Boiling point:
349.8±32.0 °C(Predicted)
Density 
1.174
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
pka
10.10±0.15(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Safety

HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21077
Product name
Deoxyarbutin
Packaging
10g
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
21077
Product name
Deoxyarbutin
Packaging
250g
Price
$593
Updated
2024/03/01
Cayman Chemical
Product number
21077
Product name
Deoxyarbutin
Packaging
50g
Price
$216
Updated
2024/03/01
Cayman Chemical
Product number
21077
Product name
Deoxyarbutin
Packaging
100g
Price
$263
Updated
2024/03/01
TRC
Product number
D232105
Product name
Deoxyarbutin
Packaging
50mg
Price
$105
Updated
2021/12/16
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Deoxyarbutin Chemical Properties,Usage,Production

Description

Deoxyarbutin is a tyrosinase inhibitor (IC50 = 17.5 μM for mushroom tyrosinase). It reduces melanin content in isolated dark human melanocytes when used at a concentration of 1.56 μM. Topical administration of deoxyarbutin (5%) induces skin lightening in human skin mouse xenograft models. Deoxyarbutin also inhibits proliferation of B16/F10 murine melanoma cells (EC50 = 39.56 μM). It induces apoptosis and halts the cell cycle at the S phase in B16/F10 cells when used at a concentration of 50 μM. Deoxyarbutin (50 mg/kg) reduces tumor growth in a B16/F10 murine melanoma model.

Uses

Deoxyarbutin acts as a skin whitening agent through the inhibition of tyrosinase. A safer alternative to the use of hydroquinone and arbutin.

Preparation

Deoxyarbutin is a derivative of ?-arbutin, obtained by removal of hydroxyl groups from the glucose side-chain of ?-arbutin.

Deoxyarbutin Preparation Products And Raw materials

Raw materials

Preparation Products

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Deoxyarbutin Suppliers

China 323 Germany 1 India 5 United Kingdom 3 United States 17 Global 349
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View Lastest Price from Deoxyarbutin manufacturers

Jinan Finer Chemical Co., Ltd
Product
Deoxyarbutin 53936-56-4
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
200mt
Release date
2021-11-17
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
Product
Deoxyarbutin 53936-56-4
Price
US $18.00-18.00/kg
Min. Order
1kg
Purity
99.9
Supply Ability
5000
Release date
2024-05-10
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Deoxyarbutin 53936-56-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-05-09

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