ChemicalBook > CAS DataBase List > 5-Aminofluorescein

5-Aminofluorescein

Product Name
5-Aminofluorescein
CAS No.
3326-34-9
Chemical Name
5-Aminofluorescein
Synonyms
5-AF;FLUORESCEINAMINE;5-AFM;AMINOFLUORESCEIN;4-AMINOFLUORESCEIN;(isoMer I);5-AMINOFLUORESCEIN;1-FLUORESCEINAMINE;1-AMINOFLUORESCEIN;Fluoresceinamine I
CBNumber
CB3254491
Molecular Formula
C20H13NO5
Formula Weight
347.32
MOL File
3326-34-9.mol
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5-Aminofluorescein Property

Melting point:
223 °C (dec.)(lit.)
Boiling point:
481.89°C (rough estimate)
Density 
1.3724 (rough estimate)
refractive index 
1.5180 (estimate)
storage temp. 
room temp
solubility 
DMF: 5 mg/ml; DMSO: 5 mg/ml
pka
9.34±0.20(Predicted)
form 
powder
color 
red-brown
Water Solubility 
Soluble in water (partly), methanol (10 mg/ml), and acetone.
BRN 
48395
Stability:
Light and Moisture Sensitive
InChIKey
GZAJOEGTZDUSKS-UHFFFAOYSA-N
CAS DataBase Reference
3326-34-9(CAS DataBase Reference)
EPA Substance Registry System
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 5-amino-3',6'-dihydroxy- (3326-34-9)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
10
TSCA 
Yes
HS Code 
32049090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
201626
Product name
Fluoresceinamine, isomer I
Packaging
1g
Price
$171
Updated
2024/03/01
Sigma-Aldrich
Product number
201626
Product name
Fluoresceinamine, isomer I
Packaging
5g
Price
$636
Updated
2024/03/01
TCI Chemical
Product number
A0306
Product name
5-Aminofluorescein (isomer I)
Purity
>95.0%(HPLC)(T)
Packaging
1g
Price
$164
Updated
2024/03/01
TCI Chemical
Product number
A0306
Product name
5-Aminofluorescein (isomer I)
Purity
>95.0%(HPLC)(T)
Packaging
5g
Price
$514
Updated
2024/03/01
Alfa Aesar
Product number
J62175
Product name
Fluoresceinamine, isomer I, 96%
Packaging
1g
Price
$135
Updated
2024/03/01
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5-Aminofluorescein Chemical Properties,Usage,Production

Chemical Properties

Dark Red Solid

Uses

Glycosaminoglycuronans react with 5-aminofluorescein to yield fluorescent derivatives. 5-aminofluorescein is also used to prepare FITC Isomer I (F-011, F-020).

Uses

5-aminofluorescein is also used to prepare FITC Isomer I (CDX-F0011, CDX-F0020). It is a chemical used as molecular probe and important as fluorescent dye and for derivatives. Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens.

Definition

ChEBI: 5-aminofluorescein is a primary amino compound that is fluorescein carrying an amino substituent at C-5. Building block/intermediate for the synthesis of the fluorescent dye flourescein; also used to produce N-(fluorescein-5-yl)maleamic acid. It derives from a fluorescein (lactone form).

Preparation

The preparation of 5-aminofluorescein is carried out either by first saponification of 5-nitrofluorescein acetates with alcohol alkali, followed by reduction of the obtained 5-nitrofluorescein in a solution of alcohol alkali with hydrazine hydrate on a nickel catalyst to obtain 5-aminofluorescein , Or by boiling in an aqueous solution of sodium sulfide. The restoration of the nitro group and the saponification of acetates in the second case occurs in one stage.

General Description

Fluoresceinamine, isomer I belongs to the class of derivatized fluoresceins.

5-Aminofluorescein Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Aminofluorescein Suppliers

Hubei Jingmen Pharmaceutical Industry Technology Research Institute Co., Ltd.
Tel
18186973118
Fax
QQ:359311405
Email
359311405@qq.com
Country
China
ProdList
143
Advantage
58
Suzhouhongxiong
Tel
18051745768 18051745768
Email
Suzhouhongxiong@163.com
Country
China
ProdList
100
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
Nanjing Search Biotech Co., Ltd
Tel
+86-025-81682922 +86-13515111588
Fax
025-85860962
Email
sales@searchbio.com.cn
Country
China
ProdList
135
Advantage
68
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
999
Advantage
60
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View Lastest Price from 5-Aminofluorescein manufacturers

Hebei Duling International Trade Co. LTD
Product
5-Aminofluorescein 3326-34-9
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2023-02-28
Hebei Mojin Biotechnology Co., Ltd
Product
5-Aminofluorescein 3326-34-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-29
Hebei Guanlang Biotechnology Co., Ltd.
Product
5-Aminofluorescein 3326-34-9
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-06-23

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