Isosorbide 5-mononitrate

Product Name: Isosorbide 5-mononitrate
CAS No.: 16051-77-7
Chemical Name: Isosorbide 5-mononitrate
Synonyms: ISOSORBIDE MONONITRATE;ISMN;Ismo;IMDUR;5-ismn;Vasotrate;5-ISOSORBIDE MONONITRATE;ELAN;Momt;Coronu
CBNumber: CB3256697
Molecular Formula: C6H9NO6
Formula Weight: 191.14
MOL File: 16051-77-7.mol

More

Less

Isosorbide 5-mononitrate Property

Melting point:: 88-93 °C
alpha: 170 º (c=1, EtOH)
Boiling point:: 326.86°C (rough estimate)
Density: 1.5784 (rough estimate)
refractive index: 145 ° (C=5, H2O)
storage temp.: -20°C Freezer
solubility: Undiluted isosorbide mononitrate is freely soluble in water, in acetone, in ethanol (96 per cent) and in methylene chloride. The solubility of the diluted product depends on the diluent and its concentration.
pka: 13.09±0.40(Predicted)
form: Solid
color: White to Off-White
Water Solubility: soluble
Merck: 5225
InChIKey: YWXYYJSYQOXTPL-SLPGGIOYSA-N
CAS DataBase Reference: 16051-77-7(CAS DataBase Reference)
EPA Substance Registry System: D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate (16051-77-7)

More

Less

Safety

Hazard Codes: Xi-F,Xi,F
Risk Statements: 36/37/38-11
Safety Statements: 37/39-16-15
RIDADR: 3251
RTECS: LZ4386500
HazardClass: 4.1
HS Code: 2932999000
Toxicity: LD50 oral in rat: 2010mg/kg

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

More

Less

N-Bromosuccinimide Price

Alfa Aesar

Product number: J63674
Product name: Isosorbide mononitrate, 98+%
Packaging: 5g
Price: $193.65
Updated: 2024/03/01

Alfa Aesar

Product number: J63674
Product name: Isosorbide mononitrate, 98+%
Packaging: 10g
Price: $307.65
Updated: 2024/03/01

Alfa Aesar

Product number: J63674
Product name: Isosorbide mononitrate, 98+%
Packaging: 25g
Price: $704.65
Updated: 2024/03/01

TRC

Product number: KIT8290
Product name: Isosorbide5-Mononitrate(1.0mg/mLinDimethylSulfoxide)
Packaging: 10x1mL
Price: $180
Updated: 2021/12/16

Apolloscientific

Product number: BICL4113
Product name: Isosorbide-5-mononitrate
Purity: 99%min
Packaging: 500mg
Price: $707
Updated: 2021/12/16

More

Less

Isosorbide 5-mononitrate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

antidepressant, 5HT reuptake inhibitor

Uses

Isosorbide 5-Mononitrate is a metabolite of Isosorbide Dinitrate; used as an antianginal.

Uses

A metabolite of Isosorbide Dinitrate. Used as an antianginal

Definition

ChEBI: Isosorbide mononitrate is a nitrate ester and a glucitol derivative. It has a role as a nitric oxide donor and a vasodilator agent.

brand name

Imdur (Schering-Plough); Ismo (Dr. Reddy’s); Monoket (Schwarz Pharma) .

General Description

Isosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.

Air & Water Reactions

Highly flammable.

Reactivity Profile

The dinitrate, a heart drug, can detonate when dry, but is non explosive with 30% of water [J. Haz.. Mater., 1992, 32(1), 87]. The mononitrate would be expected to be less reactive.

Health Hazard

Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.

Clinical Use

Vasodilator:
Treatment and prophylaxis of angina
Adjunct in congestive heart failure

Isosorbide 5-mononitrate Preparation Products And Raw materials

Raw materials

D-Sorbitol Isosorbide dinitrate Sorbitol

Preparation Products

More

Less

Isosorbide 5-mononitrate Suppliers

Belgium 2 Brazil 2 Canada 1 China 307 Czech Republic 1 Europe 2 France 3 Germany 7 India 32 Ireland 1 Italy 2 Japan 3 Jordan 1 Mexico 1 Nepal 1 Philippines 1 Poland 1 Russia 1 Slovenia 1 South Korea 2 Switzerland 4 United Arab Emirates 1 United Kingdom 8 United States 29 Global 414

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Alfa Chemistry

Tel: 1-516-6625404
Fax: 1-516-927-0118
Email: support@alfa-chemistry.com
Country: United States
ProdList: 9171
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10404
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38632
Advantage: 58

CarboMer, Inc.

Tel: --
Fax: --
Email: sales@carbomer.com
Country: United States
ProdList: 4026
Advantage: 67

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

Albany Molecular Research Inc. (AMRI)

Tel: --
Fax: --
Email: Customerservice@amriglobal.com
Country: United States
ProdList: 61
Advantage: 58

Alan Scientific Inc.

Tel: --
Fax: --
Email: sales@alanscientific.com
Country: United States
ProdList: 51
Advantage: 58

Selleck Chemicals LLC

Tel: --
Fax: --
Email: sales@selleckchem.com
Country: United States
ProdList: 1848
Advantage: 58

OChem Incorporation

Tel: --
Fax: --
Email: sales@ocheminc.com
Country: United States
ProdList: 6501
Advantage: 60

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Medical Isotopes

Tel: --
Fax: --
Email: stohler@medicalisotopes.com
Country: United States
ProdList: 6181
Advantage: 68

Spectrum Chemicals & Laboratory Products

Tel: --
Fax: --
Email: sales@spectrumchemical.com
Country: United States
ProdList: 6699
Advantage: 77

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

Advance Scientific & Chemical

Tel: --
Fax: --
Email: sales@advance-scientific.com
Country: United States
ProdList: 6419
Advantage: 71

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Fine Chem Trading LTD

Tel: --
Fax: --
Email: chemfinder@chemfinder.co.uk
Country: United States
ProdList: 1609
Advantage: 64

Sciencelab.com, Inc.

Tel: --
Fax: --
Email: accounting@sciencelab.com
Country: United States
ProdList: 4159
Advantage: 82

Lab Express

Tel: --
Fax: --
Email: sales@labexpress.com
Country: United States
ProdList: 1577
Advantage: 67

LKT Laboratories, Inc.

Tel: --
Fax: --
Email: info@lktlabs.com
Country: United States
ProdList: 2164
Advantage: 64

Scandinavian Formulas, Inc.

Tel: --
Fax: --
Email: info@scandinavianformulas.com
Country: United States
ProdList: 1447
Advantage: 55

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

American Custom Chemicals Corporation

Tel: --
Fax: --
Email: sales@acccorporation.com
Country: United States
ProdList: 6820
Advantage: 51

More

Less

View Lastest Price from Isosorbide 5-mononitrate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Isosorbide 5-Mononitrate 16051-77-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-06

Hebei Yanxi Chemical Co., Ltd.

Product: isosorbide mononitrate 16051-77-7
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-09-06

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Isosorbide 5-mononitrate 16051-77-7
Price: US $65.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-10-27

16051-77-7, Isosorbide 5-mononitrateRelated Search:

Isosorbide Isosorbide dinitrate ISOSORBIDE 2-MONONITRATE,ISOSORBIDE 2-MONONITRATE 99-101.0% Sodium hydride NIVITIN DEHYDROGENASE Sorbitol Prenyl acetate isosorbide-5-mononitrate-2-glucuronide ISOSORBIDE-13C6 DINITRATE Isosorbide 5-mononitrate

IMDUR

IS-5-MN

ISOSORBIDE MONONITRATE

ISOSORBIDE 5-MONONITRATE

ISOSORBIDE 5-NITRATE

ELANTAN

ELAN

CORANGIN

5-ISOSORBIDE MONONITRATE

MONOSORB

MONOCEDOCARD

MONOCLAIR

1,4:3,6-dianhydro-,5-nitrate,d-glucito

1,4:3,6-dianhydro-d-glucito5-nitrate

1,4:3,6-dianhydro-d-glucitol5-nitrate

1,4:3,6-DIANHYDRO-D-GLUCITOL 5-MONONITRATE

6-Nitrooxy-hexahydro-furo[3,2-β]furan-3-ol

6-Nitrooxy-hexahydro-furo[3,2-b]furan-3-ol

D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate

[(1R,2R,5R,6S)-6-hydroxy-4,8-dioxabicyclo[3.3.0]oct-2-yl] nitrate

ISOSORBIDE MONO ACETATE

5-ismn

ahr4698

bm22-145

Ososoribide-5-mononitrate

ISOSORBIDE 5-MONONITRATE, 98.5%

Corangin,Elan,Elantan,Imdur,Monocedocard,Monoclair,Monosorb

1,4:3,6-Dianhydro-D-glucitol mononitrate

1,4:3,6-Dianhydro-D-glucitd 5-mononitrate

Vasotrate

ISOSORBIDE MONONITRATE(ISOSORBIDE-5-MONONITRATE)

isosorbide 5-mononitrite

Erlotinib-d17 HCl

Diluted Isosorbide Mononitrate (50%)

1,4:3,6-Dianhydro-5-O-nitro-D-erythro-hexitol

IS-5-MN (ISOSORBIDE-5-MONONITRATE

(3S,3aS,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate

Isosorbide-5-mononitrate min. 99%

Isosorbide Mononitrate EP

Coronu

Ismo

Isomonat

Momt

Monicor

Olicard

[(3R,3aS,6S,6aR)-6-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[2,3-d]furan-3-yl nitrate

5-Nitro-1,4,3,6-dianhydro-D-glucitol

6-Nitroxoyhexahydrofuro[3,2-b]furan-3-ol

8-Nitrooxy-2,6-dioxabicyclo[3.3.0]octan-4-ol

ISMN

TY-10368

Isosorbide mononitrate,contains ~30%(w/w) lactose

(3R,3aS,6S,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate

Diluted Isosorbide Mononitrate (750 mg)

Isosorbide 5-Mononitrate (1.0 mg/mL in Dimethyl Sulfoxide)

Isosorbide5-Nitrate&gt

Isosorbide mononitrate CRS

Monoket