ChemicalBook > CAS DataBase List > VU 0365114

VU 0365114

Product Name
VU 0365114
CAS No.
1208222-39-2
Chemical Name
VU 0365114
Synonyms
VU 0365114;VU 0365114, 10 mM in DMSO;1-Biphenyl-4-ylmethyl-5-trifluoromethoxy-1H-indole-2,3-dione;1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione;1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione;1-[(1,1'-Biphenyl)-4-ylmethyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione;1H-Indole-2,3-dione, 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-;VU 0365114,inhibit,Muscarinic acetylcholine receptor,VU0365114,Inhibitor,VU-0365114,mAChR
CBNumber
CB32652655
Molecular Formula
C22H14F3NO3
Formula Weight
397.35
MOL File
1208222-39-2.mol
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VU 0365114 Property

Boiling point:
526.2±60.0 °C(Predicted)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Ethanol:10.0(Max Conc. mg/mL);25.17(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);75.5(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);75.5(Max Conc. mM)
form 
Powder
pka
-3.71±0.20(Predicted)
color 
Light yellow to orange
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
4404
Product name
VU0365114
Purity
≥98%(HPLC)
Packaging
10
Price
$195
Updated
2021/12/16
Tocris
Product number
4404
Product name
VU0365114
Purity
≥98%(HPLC)
Packaging
50
Price
$793
Updated
2021/12/16
Usbiological
Product number
257068
Product name
VU 0365114
Packaging
10mg
Price
$446
Updated
2021/12/16
TRC
Product number
V787560
Product name
VU0365114
Packaging
10mg
Price
$145
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0002084
Product name
VU-0365114
Purity
95.00%
Packaging
10MG
Price
$275.1
Updated
2021/12/16
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VU 0365114 Chemical Properties,Usage,Production

Uses

VU 0365114 is a selective positive allosteric modulator of M5 (EC50 values are 2.7 μM for human M5, and >30 μM for M1, M2, M3 and M4 receptors).

Definition

ChEBI: 1-[(4-phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione is a member of biphenyls.

IC 50

mAChR5

storage

Store at RT

VU 0365114 Preparation Products And Raw materials

Raw materials

Preparation Products

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VU 0365114 Suppliers

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1208222-39-2, VU 0365114Related Search:

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide VU 0285683 N-(4-Methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide VU0134992(hydrochloride) VU6005649 VU 591 hydrochloride VU0810464 VU0483605 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin VU 6008667 (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid 4-trifluoromethanesulfonyl-benzylamide 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine VU 0360172 VU 0357121 VU 0360223 VU 0364439

  • VU 0365114
  • 1-Biphenyl-4-ylmethyl-5-trifluoromethoxy-1H-indole-2,3-dione
  • 1-[(1,1'-Biphenyl)-4-ylmethyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione
  • 1H-Indole-2,3-dione, 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-
  • VU 0365114,inhibit,Muscarinic acetylcholine receptor,VU0365114,Inhibitor,VU-0365114,mAChR
  • 1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione
  • VU 0365114, 10 mM in DMSO
  • 1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione
  • 1208222-39-2
  • Pharmaceuticals
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals