H2N-PEG5-CH2COOH
- Product Name
- H2N-PEG5-CH2COOH
- CAS No.
- 141282-35-1
- Chemical Name
- H2N-PEG5-CH2COOH
- Synonyms
- Amino-PEG5;NH2-PEG5-CH2COOH;H2N-PEG5-CH2COOH;Amino-PEG5-CH2COOH;Amino-PEG5-CH2CO5H;Amino-PEG5-CH2CO2H;AMINE-PEG5-CH2COOH;Amino-PEG5-acetic acid;Acetic acid, 2-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]aceticacid
- CBNumber
- CB32656921
- Molecular Formula
- C12H25NO7
- Formula Weight
- 295.33
- MOL File
- 141282-35-1.mol
H2N-PEG5-CH2COOH Property
- Boiling point:
- 434.2±40.0 °C(Predicted)
- Density
- 1.150±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- solubility
- DMSO : 20 mg/mL (67.72 mM; ultrasonic and warming and heat to 60°C)
- form
- Solid
- pka
- 3.39±0.10(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A619535
- Product name
- Amino-PEG5-CH2CO2H
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A619535
- Product name
- Amino-PEG5-CH2CO2H
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- A619535
- Product name
- Amino-PEG5-CH2CO2H
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- BP-22065
- Product name
- Amino-PEG5-CH2CO2H
- Purity
- 98%
- Packaging
- 1g
- Price
- $450
- Updated
- 2021/12/16
- Product number
- AS104135
- Product name
- H2N-PEG5-CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $588
- Updated
- 2021/12/16
H2N-PEG5-CH2COOH Chemical Properties,Usage,Production
Uses
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
H2N-PEG5-CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
H2N-PEG5-CH2COOH Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from H2N-PEG5-CH2COOH manufacturers
- Product
- NH2-PEG5-CH2COOH 141282-35-1
- Price
- US $433.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2025-11-17
- Product
- Amino-PEG5-CH2CO2H 141282-35-1
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-05
- Product
- Amino-PEG5-CH2COOH 141282-35-1
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-22