ChemicalBook > CAS DataBase List > GSK2110183
GSK2110183
- Product Name
- GSK2110183
- CAS No.
- 1047634-63-8
- Chemical Name
- GSK2110183
- Synonyms
- CS-1729;GSK2110183;Afuresertib-F free base;Afuresertib (GSK2110183);GSK2110183;GSK 2110183;GSK-2110183;N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)thiophene-2-carboxamide;N-((S)-1-Amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide;(S)-N-(1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide;N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide;N-[(1S)-2-Amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide
- CBNumber
- CB32715633
- Molecular Formula
- C18H16Cl2F2N4OS
- Formula Weight
- 445.31
- MOL File
- 1047634-63-8.mol
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GSK2110183 Property
- Boiling point:
- 539.7±50.0 °C(Predicted)
- Density
- 1.54±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 12.92±0.46(Predicted)
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N-Bromosuccinimide Price
Biosynth Carbosynth
- Product number
- FG103755
- Product name
- GSK 2110183
- Packaging
- 10mg
- Price
- $175
- Updated
- 2021/12/16
AK Scientific
- Product number
- 7590DN
- Product name
- N-[(2S)-1-Amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)thiophene-2-carboxamide
- Packaging
- 10mg
- Price
- $286
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FG103755
- Product name
- GSK 2110183
- Packaging
- 50mg
- Price
- $612.5
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31004719
- Product name
- GSK2110183
- Purity
- 98+%
- Packaging
- 50mg
- Price
- $1042
- Updated
- 2021/12/16
Chemenu
- Product number
- CM188229
- Product name
- (S)-N-(1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $1374
- Updated
- 2021/12/16
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GSK2110183 Chemical Properties,Usage,Production
Description
Afuresertib-F is an analogue of Afuresertib with one more flurorine-atom compared to its parent drug Afuresertib. Afuresertib-F is an ATK inhibitor. Afuresertib, also known as GSK-2110183 or GSK-2110183C, is an cancer drug candidate under clinical trial.
Uses
An ATK inhibitorAfuresertib-F is used in methods of treating myeloproliferative neoplasms using a combination of a MDM2 inhibitor and a therapeutic agent.
GSK2110183 Preparation Products And Raw materials
Raw materials
Preparation Products
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GSK2110183 Suppliers
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