Danirixin

Product Name: Danirixin
CAS No.: 954126-98-8
Chemical Name: Danirixin
Synonyms: CS-1940;CS-2750;Danirixin;GSK1325756;Danirixin HCl;Danirixin (GSK1325756);Solabegron Hydrochloride;Danirixin, 10 mM in DMSO;CXCR,GSK 1325756,Inhibitor,inhibit,Danirixin,CXC chemokine receptors,GSK-1325756;1-[4-Chloro-2-hydroxy-3-(piperidine-3-sulfonyl)-phenyl]-3-(3-fluoro-2-methyl-phenyl)-urea
CBNumber: CB73121091
Molecular Formula: C19H21ClFN3O4S
Formula Weight: 441.9
MOL File: 954126-98-8.mol

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Danirixin Property

Melting point:: >153°C (dec.)
Boiling point:: 533.1±50.0 °C(Predicted)
Density: 1.467±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Methanol (Slightly)
pka: 4.95±0.10(Predicted)
form: Solid
color: White to Light Brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20980
Product name: Danirixin
Purity: ≥98%
Packaging: 1mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 20980
Product name: Danirixin
Purity: ≥98%
Packaging: 5mg
Price: $177
Updated: 2024/03/01

Cayman Chemical

Product number: 20980
Product name: Danirixin
Purity: ≥98%
Packaging: 10mg
Price: $274
Updated: 2024/03/01

Cayman Chemical

Product number: 20980
Product name: Danirixin
Purity: ≥98%
Packaging: 25mg
Price: $632
Updated: 2024/03/01

Usbiological

Product number: 466366
Product name: Solabegron Hydrochloride
Packaging: 2.5mg
Price: $360
Updated: 2021/12/16

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Danirixin Chemical Properties,Usage,Production

Uses

Antidiabetic (β3 adrenoreceptor agonist).

Biological Activity

Danirixin (GSK1325756) is an orally active, selective CXC chemokine receptor 2 (CXCR2) antagonist with 78-fold lower affinity toward CXCR1 (CXCR2/CXCR1 IC50 = 12.5/977 nM by competitive binding against 0.225 nM [125I] CXCL8). Danirixin blocks agonist-induced neutrophil CD11b expression in vitro (IC50 = 420/890 nM against induction by 10 nM human CXCL1/r at CXCL2 using rat/human whole blood) and prevents lung neutrophils influx in rats in vivo following aerosol lipopolysaccharide or ozone challenge (ED50 = 1.4 and 16 mg/kg, respectively).

Danirixin Preparation Products And Raw materials

Raw materials

Preparation Products

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Danirixin Suppliers

China 60 United States 9 Global 69

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Wuhan ariel chemical Co., LTD.

Tel: 18986259541 18986259541
Fax: 027-87840182
Email: sales@3stc.com
Country: China
ProdList: 4008
Advantage: 58

Shanghai Hope Chem Co., Ltd.，

Tel: +21-18501659228 18501659228
Fax: sales@hope-chem.com
Email: info@hope-chem.com
Country: China
ProdList: 476
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Wuhan Kaymke Chemical Co., Ltd.,

Tel: 027-027-87342388 18086026008
Fax: 027-87342388
Email: sales@kaymke.com
Country: China
ProdList: 3850
Advantage: 55

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4573
Advantage: 55

Twochem Co.Ltd

Tel: 021-021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 304
Advantage: 55

ShangHai Angti Biotechnology Co., Ltd.

Tel: 13764913901
Fax: -
Email: info@angtibio.com
Country: China
ProdList: 5028
Advantage: 55

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 021-20242659 18930833303
Fax: +86 (21) 2024-2659
Email: Sales@changyanchem.cn
Country: China
ProdList: 5010
Advantage: 55

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View Lastest Price from Danirixin manufacturers

Career Henan Chemical Co

Product: Danirixin 954126-98-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-25

954126-98-8, DanirixinRelated Search:

N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide GSK-2126458 ABT 702 Dihydrochloride daprodustat,GSK1278863 GSK1940029 GSK 189254A GSK2110183 gsk2200150a 4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%

Danirixin

GSK1325756

Danirixin (GSK1325756)

Solabegron Hydrochloride

Danirixin HCl

1-[4-Chloro-2-hydroxy-3-(piperidine-3-sulfonyl)-phenyl]-3-(3-fluoro-2-methyl-phenyl)-urea

CS-2750

CS-1940

N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(3-fluoro-2-methylphenyl)urea

Urea, N-[4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl]-N'-(3-fluoro-2-methylphenyl)-

CXCR,GSK 1325756,Inhibitor,inhibit,Danirixin,CXC chemokine receptors,GSK-1325756

Danirixin, 10 mM in DMSO

954126-98-8