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SPERMINE TETRAHYDROCHLORIDE

Product Name
SPERMINE TETRAHYDROCHLORIDE
CAS No.
306-67-2
Chemical Name
SPERMINE TETRAHYDROCHLORIDE
Synonyms
NEURIDINE HYDROCHLORIDE;MUSCULAMINE HYDROCHLORIDE;Spermidine Tetrahydrochloride;Spermine4HCl;SPERMINE HCL;SperMine tetra;Spermidine 4HCl;Spermine, TetraHCl;Spermine-[2H8].4HCl;4-BUTANEDIAMINE 4 HCL
CBNumber
CB3275333
Molecular Formula
C10H30Cl4N4
Formula Weight
348.18
MOL File
306-67-2.mol
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SPERMINE TETRAHYDROCHLORIDE Property

Melting point:
310-311 °C (dec.)(lit.)
Density 
1.01 g/mL at 20 °C
storage temp. 
room temp
solubility 
H2O: 1 M at 20 °C, clear, colorless
form 
powder
color 
White to Almost white
PH
4.5-7.0 (25℃, 1M in H2O)
Water Solubility 
Soluble in water (348.2 g/L at 20°C).
λmax
λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.15
BRN 
3911771
InChI
InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
InChIKey
XLDKUDAXZWHPFH-UHFFFAOYSA-N
SMILES
C(CNCCCN)CCNCCCN.Cl.Cl.Cl.Cl
CAS DataBase Reference
306-67-2(CAS DataBase Reference)
EPA Substance Registry System
Spermine tetrahydrochloride (306-67-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
EJ7230000
F 
3-10
TSCA 
Yes
HS Code 
29212900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
5677
Product name
Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem
Packaging
5G
Price
$318
Updated
2024/03/01
TCI Chemical
Product number
B1468
Product name
N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride
Purity
>98.0%(N)(T)
Packaging
5g
Price
$178
Updated
2024/03/01
TCI Chemical
Product number
B1468
Product name
N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride
Purity
>98.0%(N)(T)
Packaging
25g
Price
$827
Updated
2024/03/01
Alfa Aesar
Product number
J63060
Product name
Spermine tetrahydrochloride, 99%
Packaging
1g
Price
$35.6
Updated
2024/03/01
Alfa Aesar
Product number
J63060
Product name
Spermine tetrahydrochloride, 99%
Packaging
5g
Price
$132
Updated
2024/03/01
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SPERMINE TETRAHYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

Spermine Tetrahydrochloride is an inhibitor of NOS1, NMDA, GluR, and PLCα. A useful reactant for Surface-?enhanced Raman spectroscopy (SERS) characterization of abasic sites in DNA duplexes.

Uses

Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors and red blood cells of chicken.

Uses

Used to precipitate DNA from low salt aqueous buffers.

Biological Activity

Polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.

Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

storage

Desiccate at +4°C

Purification Methods

Its pK values are similar to those of spermidine above. Purify it as for spermidine trihydrochloride above. [Beilstein 4 IV 1301.]

SPERMINE TETRAHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SPERMINE TETRAHYDROCHLORIDE manufacturers

Shandong Huizhihan Supply Chain Co., Ltd
Product
Spermine tetrahydrochloride 306-67-2
Price
US $0.00-0.00/box
Min. Order
1box
Purity
99.99%
Supply Ability
1000
Release date
2024-10-31
Hebei Weibang Biotechnology Co., Ltd
Product
Spermine Tetrahydrochloride 306-67-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-28
Hebei Yanxi Chemical Co., Ltd.
Product
Spermine Tetrahydrochloride 306-67-2
Price
US $60.00-23.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-14

306-67-2, SPERMINE TETRAHYDROCHLORIDERelated Search:

Methotrexate L-Lysine hydrochloride Betaine hydrochloride Dimethylamine hydrochloride polyethyleneimine 1-(5-Amino-4-bromo-2-chloro-phenyl)-ethanone Trichlormethiazide Zinc stearate 1,4-DIAMINOBUTANE O,O-Dimethyl phosphoramidothioate SPERMINE TETRAHYDROCHLORIDE SPERMINE TETRAHYDROCHLORIDE 1,3-DIAMINOPROPANE DIHYDROCHLORIDE 1,4-Diaminobutane dihydrochloride Spermidine Spermidine trihydrochloride Dipentene N-METHYL-BUTANE-1,4-DIAMINE 2HCL

  • N,N'-BIS(3-AMINOPROPYL)-BUTANE-1,4-DIAMINE TETRAHYDROCHLORIDE
  • N,N'-BIS(3-AMINOPROPYL)-1,4-BUTANEDIAMINE 4 H CL
  • N,N'-BIS-(3-AMINOPROPYL)-1,4-DIAMINOBUTANE TETRAHYDROCHLORIDE
  • N,N'-BIS(3-AMINOPROPYL)-1,4-BUTANEDIAMINE TETRAHYDROCHLORIDE
  • NEURIDINE HYDROCHLORIDE
  • NEURIDINE TETRAHYDROCHLORIDE
  • MUSCULAMINE HYDROCHLORIDE
  • MUSCULAMINE TETRAHYDROCHLORIDE
  • SPERMINE HYDROCHLORIDE
  • SPERMINE TETRAHYDROCHLORIDE
  • DIAMINOPROPYLTETRAMETHYLENEDIAMINE HYDROCHLORIDE
  • GERONTINE TETRAHYDROCHLORIDE
  • 1,4-BIS(AMINOPROPYL)BUTANEDIAMINE TETRAHYDROCHLORIDE
  • 1,4-Butanediamine,N,N’-bis(3-aminopropyl)-,tetrahydrochloride
  • n1,n4-bis(3-aMinopropyl)-1,4-butanediaMine hydrochloride
  • N1,N1'-(butane-1,4-diyl)bis(propane-1,3-diaMine) tetrahydrochloride
  • SperMine tetra
  • Spermine tetrahydrochloride solution
  • Spermine tetrahydrochloride Vetec(TM) reagent grade
  • <i>N</i>,<i>N</i>'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride
  • SPERMINE TETRAHYDROCHLORIDE BIOREAGE
  • SPERMINE TETRAHYDROCHLORIDE BIOULTRA
  • Spermine tetrahydrochloride≥ 99% (GC)
  • Spermine Tetra HCl salt
  • 4-butanediamine,n,n’-bis(3-aminopropyl)-tetrahydrochloride
  • 4,9-diazoniadodecamethylenediammonium tetrachloride
  • Spermine, TetraHCl
  • SPERMINE TETRAHYDROCHLORIDE MOLECULAR*BI OLOGY REAGE
  • SPERMINE TETRAHYDROCHLORIDE, F. MOLE-CUL AR BIOLOGY
  • Spermine tetrahydrochloride 0.1 M Solution
  • Spermine4HCl
  • Additive Screening Solution 31/Fluka kit no 78374, Spermine tetrahydrochloride solution
  • additive screening solution 31/fluka kit no 78374
  • SPERMINETETRAHYDROCHLORIDE,BIOTECHGRADE
  • SPERMINE HCL
  • Spermine tetrahydrochloride,N,N′-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
  • Spermine-[2H8].4HCl
  • NEURIDINE HYDROCHLORI
  • 1,4-Butanediamine,N1,N4-bis(3-aminopropyl)-, hydrochloride (1:4)
  • Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem
  • )-1,4-butanediamine TetrahydrochL
  • N,N'-Bis(3-aminopropyL
  • N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride &gt
  • Spermidine Tetrahydrochloride
  • Spermine Tetrahydrochloride extrapure, 99%
  • Spermine tetrahydrochloride（SPT）
  • 4-BUTANEDIAMINE 4 HCL
  • N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride
  • N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride
  • Spermidine 4HCl
  • Spermine tetrahydrochloride, polyamine used for precipitation of DNA
  • 306-67-2
  • C10H26N44HCl
  • C10H30Cl4N4
  • C10H26N44ClH
  • C10H26N4HCl
  • C10H30N6O2Cl4
  • C10H20N44HCl