Hydroxy-PEG3-t-butylester
- Product Name
- Hydroxy-PEG3-t-butylester
- CAS No.
- 133803-81-3
- Chemical Name
- Hydroxy-PEG3-t-butylester
- Synonyms
- TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE;HO-PEG2-CH2CH2COOtBu;OH-PEG2-TBA;HO-PEG2-COOtBu;OH-PEG2-CH2CH2COOtBu;HO-PEG2-t-Butyl ester;Hydroxy-PEG2-(CH2)2-Boc;Hydroxy-PEG3-t-butylester;Hydroxy-PEG2-t-butyl ester;tert-Butyl PEG2 propanoate
- CBNumber
- CB33048721
- Molecular Formula
- C11H22O5
- Formula Weight
- 234.29
- MOL File
- 133803-81-3.mol
Hydroxy-PEG3-t-butylester Property
- Boiling point:
- 321.8±22.0 °C(Predicted)
- Density
- 1.046±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in DMSO
- form
- clear liquid
- pka
- 14.36±0.10(Predicted)
- color
- Colorless to Almost colorless
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P2719
- Product name
- PEG3-carboxylic Acid tert-Butyl Ester
- Packaging
- 1G
- Price
- $53
- Updated
- 2024/03/01
- Product number
- P2719
- Product name
- PEG3-carboxylic Acid tert-Butyl Ester
- Packaging
- 5G
- Price
- $258
- Updated
- 2024/03/01
- Product number
- H953233
- Product name
- Hydroxy-PEG2-t-butylEster
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CS-0058621
- Product name
- Hydroxy-PEG2-(CH2)2-Boc
- Purity
- ≥97.0%
- Packaging
- 5g
- Price
- $215
- Updated
- 2021/12/16
- Product number
- BP-20520
- Product name
- Hydroxy-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 5G
- Price
- $225
- Updated
- 2021/12/16
Hydroxy-PEG3-t-butylester Chemical Properties,Usage,Production
Description
Hydroxy-PEG2-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Hydroxy-PEG2-(CH2)2-Boc is an ADC linker for the synthesis of antibody drug conjugates (ADC), Hydroxy-PEG2-(CH2)2-Boc is derived from patent WO2004008101A2 (compound 196). Hydroxy-PEG2-(CH2)2-Boc can also be used as a PROTAC linker for PROTAC synthesis.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Hydroxy-PEG3-t-butylester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Hydroxy-PEG3-t-butylester manufacturers
- Product
- Hydroxy-PEG2-t-butyl ester 133803-81-3
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-25
- Product
- tert-butyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate 133803-81-3
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-07-09