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Hydroxy-PEG3-t-butylester

Product Name
Hydroxy-PEG3-t-butylester
CAS No.
133803-81-3
Chemical Name
Hydroxy-PEG3-t-butylester
Synonyms
TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE;HO-PEG2-CH2CH2COOtBu;OH-PEG2-TBA;HO-PEG2-COOtBu;OH-PEG2-CH2CH2COOtBu;HO-PEG2-t-Butyl ester;Hydroxy-PEG2-(CH2)2-Boc;Hydroxy-PEG3-t-butylester;Hydroxy-PEG2-t-butyl ester;tert-Butyl PEG2 propanoate
CBNumber
CB33048721
Molecular Formula
C11H22O5
Formula Weight
234.29
MOL File
133803-81-3.mol
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Hydroxy-PEG3-t-butylester Property

Boiling point:
321.8±22.0 °C(Predicted)
Density 
1.046±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in DMSO
form 
clear liquid
pka
14.36±0.10(Predicted)
color 
Colorless to Almost colorless
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
P2719
Product name
PEG3-carboxylic Acid tert-Butyl Ester
Packaging
1G
Price
$53
Updated
2024/03/01
TCI Chemical
Product number
P2719
Product name
PEG3-carboxylic Acid tert-Butyl Ester
Packaging
5G
Price
$258
Updated
2024/03/01
TRC
Product number
H953233
Product name
Hydroxy-PEG2-t-butylEster
Packaging
500mg
Price
$110
Updated
2021/12/16
ChemScene
Product number
CS-0058621
Product name
Hydroxy-PEG2-(CH2)2-Boc
Purity
≥97.0%
Packaging
5g
Price
$215
Updated
2021/12/16
BroadPharm
Product number
BP-20520
Product name
Hydroxy-PEG2-t-butylester
Purity
98%
Packaging
5G
Price
$225
Updated
2021/12/16
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Hydroxy-PEG3-t-butylester Chemical Properties,Usage,Production

Description

Hydroxy-PEG2-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Hydroxy-PEG2-(CH2)2-Boc is an ADC linker for the synthesis of antibody drug conjugates (ADC), Hydroxy-PEG2-(CH2)2-Boc is derived from patent WO2004008101A2 (compound 196). Hydroxy-PEG2-(CH2)2-Boc can also be used as a PROTAC linker for PROTAC synthesis.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Hydroxy-PEG3-t-butylester Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxy-PEG3-t-butylester Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from Hydroxy-PEG3-t-butylester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Hydroxy-PEG2-t-butyl ester 133803-81-3
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-25
Career Henan Chemical Co
Product
tert-butyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate 133803-81-3
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-09

133803-81-3, Hydroxy-PEG3-t-butylesterRelated Search:


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  • OH-PEG2-CH2CH2COOtBu
  • OH-PEG2-TBA
  • HO-PEG2-t-Butyl ester
  • Hydroxy-PEG2-t-butyl ester
  • TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE
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  • tert-Butyl 9-Hydroxy-4,7-dioxanonanoate
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  • tert-Butyl PEG2 propanoate
  • 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic Acid tert-Butyl Ester
  • 9-Hydroxy-4,7-dioxanonanoic Acid tert-Butyl Ester
  • HO-(CH2CH2O)2-CH2CH2COOt-Bu
  • HO-PEG2-CH2CH2COOtBu/Propanoic acid, 3-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester
  • 133803-81-3
  • peg