ChemicalBook > CAS DataBase List > PF-5190457

PF-5190457

Product Name
PF-5190457
CAS No.
1334782-79-4
Chemical Name
PF-5190457
Synonyms
PF-5190457;PF-05190457;PF-05190457 >=95% (HPLC);PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit;1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone;(R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone;Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-;(R)-2-(2-Methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one
CBNumber
CB33303958
Molecular Formula
C29H32N6OS
Formula Weight
512.67
MOL File
1334782-79-4.mol
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PF-5190457 Property

Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: 250 mg/mL (487.64 mM)
pka
8.38±0.20(Predicted)
form 
powder
color 
white to beige
optical activity
[α]/D +45 to +55°, c = 0.5 in methanol
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PZ0270
Product name
PF-05190457
Purity
≥95% (HPLC)
Packaging
5MG
Price
$115
Updated
2023/06/20
Sigma-Aldrich
Product number
PZ0270
Product name
PF-05190457
Purity
≥95% (HPLC)
Packaging
25MG
Price
$451
Updated
2023/06/20
Tocris
Product number
6350
Product name
PF05190457
Purity
≥98%(HPLC)
Packaging
25
Price
$332
Updated
2021/12/16
Tocris
Product number
6350
Product name
PF05190457
Purity
≥98%(HPLC)
Packaging
5
Price
$86
Updated
2021/12/16
TRC
Product number
P293935
Product name
PF5190457
Packaging
10mg
Price
$145
Updated
2021/12/16
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PF-5190457 Chemical Properties,Usage,Production

Uses

PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist.

Biochem/physiol Actions

PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.

storage

Store at -20°C

PF-5190457 Preparation Products And Raw materials

Raw materials

Preparation Products

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PF-5190457 Suppliers

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1334782-79-4, PF-5190457Related Search:


  • PF-5190457
  • PF-05190457
  • 1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone
  • PF-05190457 >=95% (HPLC)
  • PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit
  • Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-
  • (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone
  • (R)-2-(2-Methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one
  • 1334782-79-4