PF-5190457
- Product Name
- PF-5190457
- CAS No.
- 1334782-79-4
- Chemical Name
- PF-5190457
- Synonyms
- PF-5190457;PF-05190457;PF-05190457 >=95% (HPLC);PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit;1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone;(R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone;Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-;(R)-2-(2-Methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one
- CBNumber
- CB33303958
- Molecular Formula
- C29H32N6OS
- Formula Weight
- 512.67
- MOL File
- 1334782-79-4.mol
PF-5190457 Property
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMSO: 250 mg/mL (487.64 mM)
- pka
- 8.38±0.20(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +45 to +55°, c = 0.5 in methanol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- PZ0270
- Product name
- PF-05190457
- Purity
- ≥95% (HPLC)
- Packaging
- 5MG
- Price
- $115
- Updated
- 2023/06/20
- Product number
- PZ0270
- Product name
- PF-05190457
- Purity
- ≥95% (HPLC)
- Packaging
- 25MG
- Price
- $451
- Updated
- 2023/06/20
- Product number
- 6350
- Product name
- PF05190457
- Purity
- ≥98%(HPLC)
- Packaging
- 25
- Price
- $332
- Updated
- 2021/12/16
- Product number
- 6350
- Product name
- PF05190457
- Purity
- ≥98%(HPLC)
- Packaging
- 5
- Price
- $86
- Updated
- 2021/12/16
- Product number
- P293935
- Product name
- PF5190457
- Packaging
- 10mg
- Price
- $145
- Updated
- 2021/12/16
PF-5190457 Chemical Properties,Usage,Production
Uses
PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist.
Biochem/physiol Actions
PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
storage
Store at -20°C
PF-5190457 Preparation Products And Raw materials
Raw materials
Preparation Products
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