ChemicalBook > CAS DataBase List > PF-06700841 tosylate
PF-06700841 tosylate
- Product Name
- PF-06700841 tosylate
- CAS No.
- 1883299-62-4
- Chemical Name
- PF-06700841 tosylate
- Synonyms
- PF841;PF 841;PF-841;CS-2861;PF6700841;PF 6700841;PF-6700841;PF-06700841 tosylate;Brepocitinib (PF-06700841);inhibit,Janus kinase,PF06700841,JAK,Brepocitinib,Inhibitor,PF 06700841
- CBNumber
- CB94674167
- Molecular Formula
- C18H21F2N7O
- Formula Weight
- 389.4
- MOL File
- 1883299-62-4.mol
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PF-06700841 tosylate Property
- Boiling point:
- 637.1±65.0 °C(Predicted)
- Density
- 1.63±0.1 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMSO: 78 mg/mL (200.31 mM);Ethanol: 78 mg/mL (200.31 mM)
- form
- powder
- pka
- 7.28±0.10(Predicted)
- color
- white to beige
- Water Solubility
- Water: Insoluble
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PZ0345
- Product name
- PF-06700841 tosylate salt
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $114
- Updated
- 2024/03/01
Biorbyt Ltd
- Product number
- orb573132
- Product name
- PF-06700841 tosylate
- Purity
- >98%
- Packaging
- 100mg
- Price
- $1283.5
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573132
- Product name
- PF-06700841 tosylate
- Purity
- >98%
- Packaging
- 250mg
- Price
- $2245.7
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573132
- Product name
- PF-06700841 tosylate
- Purity
- >98%
- Packaging
- 1g
- Price
- $4766.8
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC12489
- Product name
- PF-06700841freebase
- Purity
- >98%
- Packaging
- 1g
- Price
- $3200
- Updated
- 2021/12/16
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PF-06700841 tosylate Chemical Properties,Usage,Production
Uses
PF-06700841 tosylate salt has been used as an inhibitor of Janus kinase1 (JAK1) to study its therapeutic effect on the adjuvant induced arthritis (AIA) rat model. It has also been used as an inhibitor of interferon-α/β receptor alpha chain (IFNAR1) signaling adaptor tyrosine kinase (2TYK2) in mice.
Biochem/physiol Actions
PF-06700841 prevents IL-23 (interleukin 23) signaling through TYK2 (Tyrosine-protein kinase 2)/JAK1 (Janus kinase 1) inhibition.
PF-06700841 tosylate Preparation Products And Raw materials
Raw materials
Preparation Products
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