PF-6274484

Product Name: PF-6274484
CAS No.: 1035638-91-5
Chemical Name: PF-6274484
Synonyms: PF-6274484;PF-6274484 >=98% (HPLC);N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)acrylamide;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-;oxidation,autophosphorylation,PF6274484,PF-6274484,EGFR,signaling,Epidermal growth factor receptor,HER1,protein,ErbB-1,inhibit,kinase,cysteine,Inhibitor
CBNumber: CB14666748
Molecular Formula: C18H14ClFN4O2
Formula Weight: 372.78
MOL File: 1035638-91-5.mol

More

Less

PF-6274484 Property

storage temp.: Store at -20°C
solubility: DMF: 33 mg/ml; DMSO: 25 mg/ml
form: A crystalline solid

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 22698
Product name: PF-6274484
Purity: ≥98%
Packaging: 1mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 22698
Product name: PF-6274484
Purity: ≥98%
Packaging: 5mg
Price: $100
Updated: 2024/03/01

Cayman Chemical

Product number: 22698
Product name: PF-6274484
Purity: ≥98%
Packaging: 10mg
Price: $166
Updated: 2024/03/01

TRC

Product number: P294153
Product name: PF6274484
Packaging: 50mg
Price: $820
Updated: 2021/12/16

AK Scientific

Product number: 8711DW
Product name: N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide
Packaging: 5mg
Price: $209
Updated: 2021/12/16

More

Less

PF-6274484 Chemical Properties,Usage,Production

Description

PF-6274484 is an irreversible EGFR kinase inhibitor that covalently reacts with active-site cysteine residues in the ATP binding pocket. PF-6274484 inhibits autophosphorylation of both wild type and mutant EGFR in tumor cells with IC50 values of 5.8 nM and 6.6 nM, respectively.

PF-6274484 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PF-6274484 Suppliers

China 13 United Kingdom 1 United States 3 USA 1 Global 18

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 3412
Advantage: 55

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29797
Advantage: 68

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6870
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
ProdList: 4134
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 8000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Email: product02@bidepharm.com
Country: China
ProdList: 61788
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24131
Advantage: 58

1035638-91-5, PF-6274484Related Search:

4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester PF 03463275 PF-06446846 HYDROCHLORIDE PF-CBP-1.HCl PF 05105679 N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide PF 573228 PF-06882961 6-chloro-5-(4-(1-hydroxycyclobutyl)phenyl)-1H-indole-3-carboxylicacid PF-04979064 PF-3758309 PF-05212384 PF-06281355 PF-562271 Ketohexokinase inhibitor 1 PF-9366 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione

PF-6274484

N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide

2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-

PF-6274484 >=98% (HPLC)

oxidation,autophosphorylation,PF6274484,PF-6274484,EGFR,signaling,Epidermal growth factor receptor,HER1,protein,ErbB-1,inhibit,kinase,cysteine,Inhibitor

N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)acrylamide

1035638-91-5