4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide

Product Name: 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
CAS No.: 947303-87-9
Chemical Name: 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
Synonyms: CS-122;PF 429242;-4-((Diethylamino);PF-429242;PF429242;-N-(pyrrolidin-3-yl);-N-(2-methoxyphenethyl);PF-429242 (hydrochloride);PF-429242 dihydrochloride;4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide;o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
CBNumber: CB12554348
Molecular Formula: C25H35N3O2
Formula Weight: 409.57
MOL File: 947303-87-9.mol

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4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Property

Boiling point:: 562.2±50.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: H2O: soluble15mg/mL, clear
form: powder
pka: 9.47±0.10(Predicted)
color: white to beige
InChIKey: XKPJTOHUPQWSOJ-HSZRJFAPSA-N

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Safety

Hazard Codes: Xi,N
Risk Statements: 36/37/38-50
Safety Statements: 26-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0667
Product name: PF-429242 dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $152
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0667
Product name: PF-429242 dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $241.6
Updated: 2024/03/01

Cayman Chemical

Product number: 15140
Product name: PF-429242 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $38
Updated: 2021/12/16

Cayman Chemical

Product number: 15140
Product name: PF-429242 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $105
Updated: 2021/12/16

Cayman Chemical

Product number: 15140
Product name: PF-429242 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $190
Updated: 2021/12/16

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4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Chemical Properties,Usage,Production

Uses

PF 429242 is a novel subtilisin kexin isozyme-1/site-1 (SKI-1/S1P) protease inhibitor. PF 429242 is a sterol regulatory element-binding protein1 (SREBP1) inhibitor and has been shown to decrease pancreatic cancer cell viability and proliferation.

Biochem/physiol Actions

PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV.

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Suppliers

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Shanghai Boyle Chemical Co., Ltd.

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View Lastest Price from 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide manufacturers

Career Henan Chemical Co

Product: 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide 947303-87-9
Price: US $1.00/g
Min. Order: 100g
Purity: 99%
Supply Ability: G/KG/T
Release date: 2019-12-20

947303-87-9, 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamideRelated Search:

PF-06446846 HYDROCHLORIDE PF-CBP-1.HCl PF 05105679 N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide PF 573228 PF-06882961 6-chloro-5-(4-(1-hydroxycyclobutyl)phenyl)-1H-indole-3-carboxylicacid PF-04979064 PF-3758309 PF-05212384 PF-06281355 PF-562271 Ketohexokinase inhibitor 1 PF-6274484 PF-9366 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione PF06869206 1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide

PF 429242

o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide

4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide

PF-429242 dihydrochloride

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-benzamide dihydrochloride

Benzamide, 4-[(diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-

-4-((Diethylamino)

-N-(2-methoxyphenethyl)

-N-(pyrrolidin-3-yl)

PF-429242 (hydrochloride)

(R)-4-((DiethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide

PF-429242;PF429242

CS-122

4-(diethylaminomethyl)-N-[2-(2-methoxyphenyl)ethyl]-N-[(3R)-pyrrolidin-3-yl]benzamide

(R)-4-((Diethylamino)methyl)-N-(2-methoxyphenethyl)-N-(pyrrolidin-3-yl)benzamide dihydrochloride

947303-87-9

C25H35N3O22HCl

C25H35N3O2