ChemicalBook > CAS DataBase List > 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide

Product Name
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
CAS No.
947303-87-9
Chemical Name
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
Synonyms
CS-122;PF 429242;-4-((Diethylamino);PF-429242;PF429242;-N-(pyrrolidin-3-yl);-N-(2-methoxyphenethyl);PF-429242 (hydrochloride);PF-429242 dihydrochloride;4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide;o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
CBNumber
CB12554348
Molecular Formula
C25H35N3O2
Formula Weight
409.57
MOL File
947303-87-9.mol
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4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Property

Boiling point:
562.2±50.0 °C(Predicted)
Density 
1.11±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
H2O: soluble15mg/mL, clear
form 
powder
pka
9.47±0.10(Predicted)
color 
white to beige
InChIKey
XKPJTOHUPQWSOJ-HSZRJFAPSA-N
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Safety

Hazard Codes 
Xi,N
Risk Statements 
36/37/38-50
Safety Statements 
26-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0667
Product name
PF-429242 dihydrochloride
Purity
≥98% (HPLC)
Packaging
5mg
Price
$152
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0667
Product name
PF-429242 dihydrochloride
Purity
≥98% (HPLC)
Packaging
25mg
Price
$241.6
Updated
2024/03/01
Cayman Chemical
Product number
15140
Product name
PF-429242 (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$38
Updated
2021/12/16
Cayman Chemical
Product number
15140
Product name
PF-429242 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$105
Updated
2021/12/16
Cayman Chemical
Product number
15140
Product name
PF-429242 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$190
Updated
2021/12/16
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4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Chemical Properties,Usage,Production

Uses

PF 429242 is a novel subtilisin kexin isozyme-1/site-1 (SKI-1/S1P) protease inhibitor. PF 429242 is a sterol regulatory element-binding protein1 (SREBP1) inhibitor and has been shown to decrease pancreatic cancer cell viability and proliferation.

Biochem/physiol Actions

PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV.

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Suppliers

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View Lastest Price from 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide manufacturers

Career Henan Chemical Co
Product
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide 947303-87-9
Price
US $1.00/g
Min. Order
100g
Purity
99%
Supply Ability
G/KG/T
Release date
2019-12-20

947303-87-9, 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamideRelated Search:

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  • 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
  • PF 429242
  • o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
  • 4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
  • PF-429242 dihydrochloride
  • 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-benzamide dihydrochloride
  • Benzamide, 4-[(diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-
  • -4-((Diethylamino)
  • -N-(2-methoxyphenethyl)
  • -N-(pyrrolidin-3-yl)
  • PF-429242 (hydrochloride)
  • (R)-4-((DiethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
  • PF-429242;PF429242
  • CS-122
  • 4-(diethylaminomethyl)-N-[2-(2-methoxyphenyl)ethyl]-N-[(3R)-pyrrolidin-3-yl]benzamide
  • (R)-4-((Diethylamino)methyl)-N-(2-methoxyphenethyl)-N-(pyrrolidin-3-yl)benzamide dihydrochloride
  • 947303-87-9
  • C25H35N3O22HCl
  • C25H35N3O2