4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
- Product Name
- 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
- CAS No.
- 947303-87-9
- Chemical Name
- 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
- Synonyms
- CS-122;PF 429242;-4-((Diethylamino);PF-429242;PF429242;-N-(pyrrolidin-3-yl);-N-(2-methoxyphenethyl);PF-429242 (hydrochloride);PF-429242 dihydrochloride;4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide;o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
- CBNumber
- CB12554348
- Molecular Formula
- C25H35N3O2
- Formula Weight
- 409.57
- MOL File
- 947303-87-9.mol
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Property
- Boiling point:
- 562.2±50.0 °C(Predicted)
- Density
- 1.11±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- H2O: soluble15mg/mL, clear
- form
- powder
- pka
- 9.47±0.10(Predicted)
- color
- white to beige
- InChIKey
- XKPJTOHUPQWSOJ-HSZRJFAPSA-N
Safety
- Hazard Codes
- Xi,N
- Risk Statements
- 36/37/38-50
- Safety Statements
- 26-61
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0667
- Product name
- PF-429242 dihydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $152
- Updated
- 2024/03/01
- Product number
- SML0667
- Product name
- PF-429242 dihydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $241.6
- Updated
- 2024/03/01
- Product number
- 15140
- Product name
- PF-429242 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $38
- Updated
- 2021/12/16
- Product number
- 15140
- Product name
- PF-429242 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- 15140
- Product name
- PF-429242 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $190
- Updated
- 2021/12/16
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Chemical Properties,Usage,Production
Uses
PF 429242 is a novel subtilisin kexin isozyme-1/site-1 (SKI-1/S1P) protease inhibitor. PF 429242 is a sterol regulatory element-binding protein1 (SREBP1) inhibitor and has been shown to decrease pancreatic cancer cell viability and proliferation.
Biochem/physiol Actions
PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV.
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Preparation Products And Raw materials
Raw materials
Preparation Products
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Suppliers
View Lastest Price from 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide manufacturers
- Product
- 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide 947303-87-9
- Price
- US $1.00/g
- Min. Order
- 100g
- Purity
- 99%
- Supply Ability
- G/KG/T
- Release date
- 2019-12-20