ChemicalBook > CAS DataBase List > 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide

Product Name
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
CAS No.
947303-87-9
Chemical Name
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
Synonyms
CS-122;PF 429242;-4-((Diethylamino);PF-429242;PF429242;-N-(pyrrolidin-3-yl);-N-(2-methoxyphenethyl);PF-429242 (hydrochloride);PF-429242 dihydrochloride;4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide;o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
CBNumber
CB12554348
Molecular Formula
C25H35N3O2
Formula Weight
409.57
MOL File
947303-87-9.mol
More
Less

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Property

Boiling point:
562.2±50.0 °C(Predicted)
Density 
1.11±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
H2O: soluble15mg/mL, clear
form 
powder
pka
9.47±0.10(Predicted)
color 
white to beige
InChIKey
XKPJTOHUPQWSOJ-HSZRJFAPSA-N
More
Less

Safety

Hazard Codes 
Xi,N
Risk Statements 
36/37/38-50
Safety Statements 
26-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0667
Product name
PF-429242 dihydrochloride
Purity
≥98% (HPLC)
Packaging
5mg
Price
$152
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0667
Product name
PF-429242 dihydrochloride
Purity
≥98% (HPLC)
Packaging
25mg
Price
$241.6
Updated
2024/03/01
Cayman Chemical
Product number
15140
Product name
PF-429242 (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$38
Updated
2021/12/16
Cayman Chemical
Product number
15140
Product name
PF-429242 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$105
Updated
2021/12/16
Cayman Chemical
Product number
15140
Product name
PF-429242 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$190
Updated
2021/12/16
More
Less

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Chemical Properties,Usage,Production

Uses

PF 429242 is a novel subtilisin kexin isozyme-1/site-1 (SKI-1/S1P) protease inhibitor. PF 429242 is a sterol regulatory element-binding protein1 (SREBP1) inhibitor and has been shown to decrease pancreatic cancer cell viability and proliferation.

Biochem/physiol Actions

PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV.

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
Advantage
64
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4554
Advantage
62
NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax
+86-27-87599188
Country
China
ProdList
1493
Advantage
55
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8878
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4674
Advantage
55
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11578
Advantage
59
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
More
Less

View Lastest Price from 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide manufacturers

Career Henan Chemical Co
Product
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide 947303-87-9
Price
US $1.00/g
Min. Order
100g
Purity
99%
Supply Ability
G/KG/T
Release date
2019-12-20

947303-87-9, 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamideRelated Search:


  • 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
  • PF 429242
  • o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
  • 4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
  • PF-429242 dihydrochloride
  • 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-benzamide dihydrochloride
  • Benzamide, 4-[(diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-
  • -4-((Diethylamino)
  • -N-(2-methoxyphenethyl)
  • -N-(pyrrolidin-3-yl)
  • PF-429242 (hydrochloride)
  • (R)-4-((DiethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
  • PF-429242;PF429242
  • CS-122
  • 4-(diethylaminomethyl)-N-[2-(2-methoxyphenyl)ethyl]-N-[(3R)-pyrrolidin-3-yl]benzamide
  • (R)-4-((Diethylamino)methyl)-N-(2-methoxyphenethyl)-N-(pyrrolidin-3-yl)benzamide dihydrochloride
  • 947303-87-9
  • C25H35N3O22HCl
  • C25H35N3O2