ChemicalBook > CAS DataBase List > PF 04995274
PF 04995274
- Product Name
- PF 04995274
- CAS No.
- 1331782-27-4
- Chemical Name
- PF 04995274
- Synonyms
- PF 04995274;PF04995274;PF 04995274;PF-04995274 >=98% (HPLC);4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol;(R)-4-((4-(((4-((Tetrahydrofuran-3-yl)oxy)benzo[d]isoxazol-3-yl)oxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol;2H-Pyran-4-ol, tetrahydro-4-[[4-[[[4-[[(3R)-tetrahydro-3-furanyl]oxy]-1,2-benzisoxazol-3-yl]oxy]methyl]-1-piperidinyl]methyl]-;Inhibitor,5-HT4,5-hydroxytryptamine Receptor,behavior,Alzheimer′s disease,PF-04995274,inhibit,PF04995274,Serotonin Receptor,5-HT Receptor,Stress-induced,PF 04995274,depressive-like
- CBNumber
- CB42668576
- Molecular Formula
- C23H32N2O6
- Formula Weight
- 432.51
- MOL File
- 1331782-27-4.mol
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PF 04995274 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:20.0(Max Conc. mg/mL);46.2(Max Conc. mM)
- form
- A crystalline solid
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28776
- Product name
- PF-04995274
- Packaging
- 5mg
- Price
- $100
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28776
- Product name
- PF-04995274
- Packaging
- 25mg
- Price
- $412
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28776
- Product name
- PF-04995274
- Packaging
- 1mg
- Price
- $34
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28776
- Product name
- PF-04995274
- Packaging
- 10mg
- Price
- $183
- Updated
- 2024/03/01
ChemScene
- Product number
- CS-0007316
- Product name
- PF-04995274
- Purity
- 99.42%
- Packaging
- 25mg
- Price
- $250
- Updated
- 2021/12/16
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PF 04995274 Chemical Properties,Usage,Production
Description
PF-04995274 is a partial agonist of the serotonin (5-HT) receptor subtypes 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E (Kis = 0.36, 0.46, 0.15, and 0.32 nM, respectively, in a radioligand binding assay). It increases cAMP levels in HEK293 cells expressing 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E receptors (EC50s = 0.47, 0.36, 0.37, and 0.26 nM, respectively, for the human recombinant receptors). PF-04995274 decreases scopolamine-induced increases in the distance traveled in the Morris water maze in rats when administered at a dose of 0.032 mg/kg.
PF 04995274 Preparation Products And Raw materials
Raw materials
Preparation Products
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PF 04995274 Suppliers
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