PF-5190457

Product Name: PF-5190457
CAS No.: 1334782-79-4
Chemical Name: PF-5190457
Synonyms: PF-5190457;PF-05190457;PF-05190457 >=95% (HPLC);PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit;1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone;(R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone;Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-
CBNumber: CB33303958
Molecular Formula: C29H32N6OS
Formula Weight: 512.67
MOL File: 1334782-79-4.mol

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PF-5190457 Property

Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: room temp
solubility: DMSO: 250 mg/mL (487.64 mM)
pka: 8.38±0.20(Predicted)
form: powder
color: white to beige
optical activity: [α]/D +45 to +55°, c = 0.5 in methanol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PZ0270
Product name: PF-05190457
Purity: ≥95% (HPLC)
Packaging: 5MG
Price: $115
Updated: 2023/06/20

Sigma-Aldrich

Product number: PZ0270
Product name: PF-05190457
Purity: ≥95% (HPLC)
Packaging: 25MG
Price: $451
Updated: 2023/06/20

Tocris

Product number: 6350
Product name: PF05190457
Purity: ≥98%(HPLC)
Packaging: 25
Price: $332
Updated: 2021/12/16

Tocris

Product number: 6350
Product name: PF05190457
Purity: ≥98%(HPLC)
Packaging: 5
Price: $86
Updated: 2021/12/16

TRC

Product number: P293935
Product name: PF5190457
Packaging: 10mg
Price: $145
Updated: 2021/12/16

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PF-5190457 Chemical Properties,Usage,Production

Uses

PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist.

Biochem/physiol Actions

PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.

storage

Store at -20°C

PF-5190457 Preparation Products And Raw materials

Raw materials

Preparation Products

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PF-5190457 Suppliers

China 30 United Kingdom 1 United States 5 Global 36

Nanjing Chemlin Chemical Co., Ltd

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Sigma-Aldrich

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Shanghai Rechem science Co., Ltd.

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Fan De(Beijing) Biotechnology Co., Ltd.

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Nanjing Meihao Pharmaceutical Technology Co., Ltd.

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TargetMol Chemicals Inc.

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InvivoChem

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1334782-79-4, PF-5190457Related Search:

PF-06700841 tosylate PF-06650833 PF-05089771 (tosylate) PF-06424439 PF-06447475 PF 3644022 PF 04995274 PF-3084014 PF 573228 PF-06882961 PF-05212384 [(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinyl-methanone methanesulfonate PF-04691502 1H-Indole-2-carboxamide, 4-methoxy-N-[(1S)-3-methyl-1-[[[(1S)-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]-3-(phosphonooxy)propyl]amino]carbonyl]butyl]- PF 477736

PF-5190457

PF-05190457

1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone

PF-05190457 >=95% (HPLC)

PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit

Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-

(R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone

1334782-79-4