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FREUND'S COMPLETE ADJUVANT

Product Name
FREUND'S COMPLETE ADJUVANT
CAS No.
9007-81-2
Chemical Name
FREUND'S COMPLETE ADJUVANT
Synonyms
FCA;F5881;abs9270;FREUND'S COMPLETE AD;FREUNDS COMPLETE ADJUVANT;FREUND'S COMPLETE ADJUVANT;FREUND'S ADJUVANT COMPLETE;ADJUVANT, COMPLETE(FREUND);Freund's Adjuvant Complete,FCA;Complete Freund's adjuvant (CFA)
CBNumber
CB3341269
Molecular Formula
C9H12FN3O5
Formula Weight
0
MOL File
Mol file
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FREUND'S COMPLETE ADJUVANT Property

storage temp. 
2-8°C
form 
cell suspension
color 
amber
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Safety

Safety Statements 
23-24/25
WGK Germany 
3
RTECS 
LS6860000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H304May be fatal if swallowed and enters airways

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P331Do NOT induce vomiting.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F5881
Product name
Freund’s Adjuvant, Complete
Purity
cell suspension
Packaging
10ml
Price
$44.6
Updated
2025/07/31
Sigma-Aldrich
Product number
344289
Product name
Freund’s Complete Adjuvant, Modified,
Packaging
1set
Price
$297
Updated
2025/07/31
Sigma-Aldrich
Product number
F5881
Product name
Freund’s Adjuvant, Complete
Purity
cell suspension
Packaging
6x10ml
Price
$138
Updated
2025/07/31
Sigma-Aldrich
Product number
F5881
Product name
Freund’s Adjuvant, Complete
Purity
cell suspension
Packaging
10x10ml
Price
$222
Updated
2025/07/31
Biosynth Carbosynth
Product number
FA97162
Product name
4-Amino-1-(beta-D-arabinofuranosyl)-5-fluoro-2(1H)-pyrimidinone
Packaging
25g
Price
$425
Updated
2021/12/16
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FREUND'S COMPLETE ADJUVANT Chemical Properties,Usage,Production

Uses

Immunization

Uses

Antigens (preferably in saline) are typically mixed with an equal volume of the adjuvant to form an emulsion.

General Description

1 Set (10 x 10 ml) each containing yellow, oily, bacterial suspension.

Biochem/physiol Actions

The mycobacteria in Complete Freund′s adjuvant attracts macrophages and other cells to the injection site which enhances the immune response. For this reason, Complete Freund′s Adjuvant is used for initial injections and Incomplete Freund′s Adjuvant for subsequent boosts.

in vivo

Complete Freund's adjuvant (CFA) induces experimental autoimmune myocarditis and neuropathic pain, with a relatively low plasma clearance rate (22%)[1][2][3][4].

Induction of experimental autoimmune myocarditis (EAM)[1]
Background
Complete Freund's adjuvant (CFA) induces myocarditis by activating the immune system and enhancing the antigen-specific immune response.
Specific Modeling Methods
Mice: A/J, BALB/c, and IL6KO BALB/c ? male ? 6-8-week-old
Administration: 5mg/ml ? s.c. ? twice
Note
(1) On day 0, all mice additionally received 500 ng of pertussis toxin (i.p.)
(2) On days 0 and 7, mice received subcutaneous injections peptide emulsified in CFA supplemented with 5 mg/mL of Mycobacterium tuberculosis, strain H37Ra.
Modeling Indicators
Histological analysis: Myocarditis severity was assessed by histology and relative heart weight.
Molecular changes: Test serum levels of total IgG, IgG1, IgG2a, IgG2b, IL-1b and IL6.
Correlated Product(s): Incomplete Freund's adjuvant (IFA) (HY-153808A); Complete Freund's adjuvant (CFA, 1 mg/ml) (HY-153808B)
Opposite Product(s): /

Induction of Neuropathic Pain[2][3]
Background
Complete Freund's adjuvant (CFA) releases inflammatory mediators TNF-α and IL-6 in body which can activate peripheral nerve endings and act on pain nerve endings, resulting in neuropathic pain[2][3].
Specific Modeling Methods
Mice: C57BL/6J ? male ? 8-week-old
Administration: 20 μl ? s.c. ? once
Note
(1) Inject Complete Freund’s Adjuvant (CFA) without dilution into the plantar area of the hind paw.
(2) Tests PWT and PWL for both hind paws corresponding to before and 24, 48, 72 h after CFA injection.
Modeling Indicators
Behavior Observation: Detect paw withdrawal threshold (PWT) and paw withdrawal latency (PWL).
Correlated Product(s): Galantamine (HY-76299)
Opposite Product(s): Mecamylamine (HY-B1395A)

Animal Model:A/J, BALB/c, and IL6KO BALB/c male mice[1]
Dosage:
Administration:Subcutaneous Injectionon (sc); injected at days 0 and 7. EAM severity was analyzed by histology on day 21 (Repeated administration of CFA to animals can cause multiple injection-site effects, the most often observed are on site granulomas and pain)
Result:Increased the relative proportion of CD11b+F4/80?monocytes and CD11b+Gr1+ granulocytes.
Expanded monocytes in the heart and in the spleen and those monocytes in the spleen make less IL-10 as well as more IL-6.

FREUND'S COMPLETE ADJUVANT Preparation Products And Raw materials

Raw materials

Preparation Products

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FREUND'S COMPLETE ADJUVANT Suppliers

China 208 Japan 3 Switzerland 1 United Kingdom 2 United States 7 Global 221
SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from FREUND'S COMPLETE ADJUVANT manufacturers

Career Henan Chemical Co
Product
FREUND'S COMPLETE ADJUVANT 9007-81-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-14

9007-81-2, FREUND'S COMPLETE ADJUVANTRelated Search:

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  • ADJUVANT, COMPLETE(FREUND)
  • ADJUVANT, COMPLETE, FREUND, H37 RV
  • IMJECT FREUND'S COMPLETE ADJUVANT
  • FCA
  • FREUNDS COMPLETE ADJUVANT
  • FREUND'S COMPLETE ADJUVANT
  • FREUND'S COMPLETE ADJUVANT, MODIFIED
  • FREUND'S COMPLETE ADJUVANT, MODIFIED, MYCOBACTERIUM BUTYRICUM
  • FREUND'S ADJUVANT COMPLETE
  • Freund's Adjuvant Complete,FCA
  • F5881
  • Immunostimulants,adjuvants, Freund's
  • 4-Amino-1-(beta-D-arabinofuranosyl)-5-fluoro-2(1H)-pyrimidinone
  • FREUND'S COMPLETE ADJUVANT USP/EP/BP
  • abs9270
  • Freunds Complete Adjuvant, FCA/CFA)
  • Freund′s Complete Adjuvant, Modified, <i>Mycobacterium butyricum</i>
  • Complete Freund's adjuvant (CFA)
  • 9007-81-2
  • Adjuvants
  • BioChemical
  • Antibody Purification and Characterization
  • Antibodies
  • Supplementary Products