Methyl 4-oxotetrahydrothiophene-3-carboxylate

Product Name: Methyl 4-oxotetrahydrothiophene-3-carboxylate
CAS No.: 2689-68-1
Chemical Name: Methyl 4-oxotetrahydrothiophene-3-carboxylate
Synonyms: AKOS 92615;methyl tetrahydro-4-oxo-3-thenoate;4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENE;4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENONE;3-Carbomethoxytetrahydrothiophene-4-one;METHYL 3-OXOTETRAHYDROTHIOPHENE4-CARBOXYLATE;METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE;Methyl 4-oxotetrahydrothiophene-3-carboxylate ,97%;Methyl 4-oxotetrahydrothiophene-3-carboxylate, 95+%;tetrahydro-4-oxo-3-thiophenecarboxylicacimethylester
CBNumber: CB3354748
Molecular Formula: C6H8O3S
Formula Weight: 160.19
MOL File: 2689-68-1.mol

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Methyl 4-oxotetrahydrothiophene-3-carboxylate Property

Melting point:: 37-38 °C
Boiling point:: 95 °C
Density: 1.309±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: Chloroform
form: Solid
pka: 10.52±0.20(Predicted)
color: Light Yellow
InChI: InChI=1S/C6H8O3S/c1-9-6(8)4-2-10-3-5(4)7/h4H,2-3H2,1H3
InChIKey: LEAKUJFYXNILRB-UHFFFAOYSA-N
SMILES: C1SCC(=O)C1C(OC)=O
EPA Substance Registry System: 3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl ester (2689-68-1)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: T294170
Product name: Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster
Packaging: 5G
Price: $440
Updated: 2021/12/16

TRC

Product number: T294170
Product name: Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster
Packaging: 25g
Price: $1650
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0030710
Product name: METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE
Purity: 95.00%
Packaging: 10G
Price: $1320.38
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0030710
Product name: METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE
Purity: 95.00%
Packaging: 1G
Price: $631.34
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 67223
Product name: Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster
Packaging: 500mg
Price: $650
Updated: 2021/12/16

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Methyl 4-oxotetrahydrothiophene-3-carboxylate Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

Methyl 4-oxotetrahydrothiophene-3-carboxylate is used in the preparation of a new class of neuroleptic agents.

Synthesis

2,3,4,5-Tetrahydro-4-oxo-3-thiophene carboxylic acid, methyl ester (L75a): 25.3 g (1.1 mol) of sodium were implemented in 190 mL abs. methanol to methylate. To methylate solution 70 g (0.360 mol) (L74) was added dropwise at the boiling point and the reaction mixture was heated for 45 min under reflux. The cooling mixture was poured onto a mixture of 500 mL ice and 300 mL water, acidified with 100 mL conc. HCl and the oily precipitating product was brought to crystallize under cooling with ice/sodium chloride bath. The crystals were sucked off, resumed in 100 mL methylene chloride and dried over sodium sulfate and evaporated. There were obtained 16.7 g of pale beige crystals. The aqueous phase was extracted three times with 100 mL of methylene chloride, the organic phase dried over sodium sulfate and evaporated. 30 g of crystalline product Methyl 4-oxotetrahydrothiophene-3-carboxylate was obtained. Yield: 46.7 g of light beige crystals (81 % of theory). mp 29-31 degC. TLC: Bz:MeOH:AcOH = 45:8:4, Rf = 0.75.

Methyl 4-oxotetrahydrothiophene-3-carboxylate Preparation Products And Raw materials

Raw materials

Methyl thioglycolate Toluene Sodium Methoxide Methyl acrylate

Preparation Products

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Methyl 4-oxotetrahydrothiophene-3-carboxylate Suppliers

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View Lastest Price from Methyl 4-oxotetrahydrothiophene-3-carboxylate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Methyl 4-oxotetrahydrothiophene-3-carboxylate 2689-68-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-22

Career Henan Chemical Co

Product: METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE 2689-68-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 85.0-99.8%
Supply Ability: 20ton
Release date: 2019-12-20

2689-68-1, Methyl 4-oxotetrahydrothiophene-3-carboxylate Related Search:

HYDROXYECTOINE TERT-BUTYL 4-OXOCYCLOHEXANECARBOXYLATE Tetrahydrothiophene METHYL 3-OXOTETRAHYDROTHIOPHENE-2-CARBOXYLATE Methyl 4-oxotetrahydrothiophene-3-carboxylate 3-MERCAPTOISOBUTYRIC ACID 4-OXOTETRAHYDROTHIOPHENE-2,3-DICARBOXYLIC ACID DIMETHYL ESTER Tetrahydrothiophen-3-one 4-Mercapto-2-butanone 2-METHYL-1-BUTANETHIOL 1-(Methylthio)-2-butanone 4-METHYLTETRAHYDROTHIOPHEN-3-ONE 3-Methylthiolane METHYL 4-(METHYLTHIO)BUTYRATE

4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENONE

AKOS 92615

tetrahydro-4-oxo-3-thiophenecarboxylicacimethylester

METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE

methyl tetrahydro-4-oxo-3-thenoate

4-Oxo-Tetrahydro-Thiophene-3-CarboxylicAcidMethylEster

4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENE

Methyl 4-oxotetrahydrothiophene-3-carboxylate, 95+%

METHYL 3-OXOTETRAHYDROTHIOPHENE4-CARBOXYLATE

Tetrahydro-4-oxo-3-thiophenecarboxylic acid methyl ester

Methyl 4-oxotetrahydrothiophene-3-carboxylate ,97%

Methyl 4-oxotetrahydrothiophene-3-carboxylate , Tech.

3-(Methoxycarbonyl)-4-oxotetrahydrothiophene, 3-(Methoxycarbonyl)-4-oxothiolane

Methyl 4-oxotetrahydrothiophene-3-carboxylate, technical

METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE ISO 9001：2015 REACH

4-Oxytetrahydrophenol-3-carboxylic acid methyl ester

3-Carbomethoxytetrahydrothiophene-4-one

2689-68-1

KETONE

Esters

Thiophenes & Benzothiophenes