Fmoc-Trp(Boc)-OH

Product Name: Fmoc-Trp(Boc)-OH
CAS No.: 143824-78-6
Chemical Name: Fmoc-Trp(Boc)-OH
Synonyms: FMOC-L-TRP(BOC)-OH;FMOC-TRP(BOC);FMOC-L-TRP(BOC);N1-Boc-NaL;pha-Fmoc-L;FMOC-TRP(BOC)-OH;Fomc-Trp(Boc)-OH;Fmoc-Trp(Boc)-0H;FMOC-L-TRYPTOPHANE;FMOC-L-TRP(TBOC)-OH
CBNumber: CB3360314
Molecular Formula: C31H30N2O6
Formula Weight: 526.58
MOL File: 143824-78-6.mol

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Fmoc-Trp(Boc)-OH Property

Melting point:: ca 97℃
alpha: -21 º (c=1%, DMF)
Density: 1.28±0.1 g/cm3(Predicted)
refractive index: -20 ° (C=1, DMF)
storage temp.: 2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 3.71±0.10(Predicted)
form: Solid
color: White to Orange to Green
optical activity: [α]20/D 21±2°, c = 1% in DMF
Sensitive: Moisture Sensitive
BRN: 7698009
InChIKey: ADOHASQZJSJZBT-SANMLTNESA-N
SMILES: C(O)(=O)[C@H](CC1C2=C(C=CC=C2)N(C(OC(C)(C)C)=O)C=1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference: 143824-78-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,N
Risk Statements: 36/37/38-51/53-43
Safety Statements: 22-24/25-36/37/39-27-26-61-37-24
RIDADR: 3077
WGK Germany: 3
F: 10-21
HazardClass: 9
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H401Toxic to aquatic life

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52050
Product name: Fmoc-Trp(Boc)-OH
Purity: Novabiochem?
Packaging: 25g
Price: $196
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.52050
Product name: Fmoc-Trp(Boc)-OH
Purity: Novabiochem?
Packaging: 100g
Price: $511
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.52050
Product name: Fmoc-Trp(Boc)-OH
Purity: Novabiochem?
Packaging: 250g
Price: $1090
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.52050
Product name: Fmoc-Trp(Boc)-OH
Purity: Novabiochem?
Packaging: 1kg
Price: $4080
Updated: 2024/03/01

Sigma-Aldrich

Product number: 47561
Product name: Fmoc-Trp(Boc)-OH
Purity: ≥97.0% (HPLC)
Packaging: 5G
Price: $71.2
Updated: 2024/03/01

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Fmoc-Trp(Boc)-OH Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

Fmoc-Trp(Boc)-OH is a very useful synthetic intermediate. It is used to prepare Trp containing-peptides.

Uses

Fmoc-Trp(Boc)-OH can be used for the synthesis of analogs of glucagon-like peptide-1 (GLP-1) for the treatment of type 2 diabetes and various peptides by Fmoc solid phase peptide synthesis (SPPS).

General Description

The use of this N-in-Boc protected derivative overcomes most of the problems associated with the preparation of Trp containing-peptides by Fmoc SPPS [1]. Cleavage with TFA generates an N-in-carboxy indole which protects the Trp from alkylation [1, 2, 3] and sulfonation [1, 4, 5, 6, 7]. The N-in-carboxy group is removed under aqueous conditions during normal work-up of the peptide.

The product number for this product was previously 04-12-1103.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Fmoc-Trp(Boc)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-Trp(Boc)-OH Suppliers

Americas 1 Canada 2 China 361 Europe 5 France 2 Germany 7 India 11 Japan 4 Poland 1 South Korea 1 Switzerland 7 United Kingdom 15 United States 52 Global 469

Christof Senn Laboratories AG

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AXXORA, LLC

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Alexis Corporation

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Senn Chemicals AG

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View Lastest Price from Fmoc-Trp(Boc)-OH manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Fmoc-Trp(Boc)-OH 143824-78-6
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kg
Release date: 2021-08-28

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Fmoc-Trp(Boc)-OH 143824-78-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-12-06

Wuhan Senwayer Century Chemical Co.,Ltd

Product: Fmoc-Trp(Boc)-OH 143824-78-6
Price: US $0.00/gram
Min. Order: 25gram
Purity: 99% HPLC
Supply Ability: 25 gram
Release date: 2023-10-16

143824-78-6, Fmoc-Trp(Boc)-OHRelated Search:

Fmoc-Lys(Boc)-OH L-Tryptophan BUTYL OLEATE 9-Fluorenylmethyl chloroformate tert-Butyl acetate N-(tert-Butoxycarbonyl)-L-alanine L-5-Hydroxytryptophan Fmoc-Phe-OH Nalpha-Fmoc-Ndelta-trityl-L-glutamine L-Fmoc-Aspartic acid alpha-tert-butyl ester METHOXYCARBONYLSULFENYL CHLORIDE Cyhalofop-butyl Butyl acetate N-(9-Fluorenylmethoxycarbonyloxy)succinimide Boc-Aib-OH 2-Butoxyethanol Buprofezin tert-Butanol

FMOC-TRP(BOC)-OH

FMOC-TRP(BOC)

FMOC-TRYPTOPHAN(BOC)-OH

FMOC-NIN-T-BUTYLOXYCARBONYL-L-TRYPTOPHAN

FMOC-N-IN-BOC-L-TRYPTOPHAN

FMOC-N-BOC-L-TRYPTOPHAN

FMOC-L-TRP(BOC)

FMOC-L-TRP(BOC)-OH

FMOC-L-TRYPTOPHAN(BOC)

FMOC-L-TRYPTOPHAN (TBOC)

FMOC-L-TRP(TBOC)-OH

N-ALPHA-FMOC-N-IN-T-BOC-L-TRYPTOPHAN

N-ALPHA-FMOC-N(IN)-BOC-L-TRYPTOPHAN

N-ALPHA-FMOC-N-IN-TERT-BOC-L-TRYPTOPHAN

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-IN-T-BUTOXYCARBONYL-L-TRYPTOPHAN

N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-NIN-T-BUTYLOXYCARBONYL-L-TRYPTOPHAN

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-IN-T-BUTYL-OXYCARBONYL-L-TRYPTOPHAN

NALPHA-9-FLUORENYLMETHYLOXYCARBONYL-N(IN)-TERT-BUTOXYCARBONYL-L-TRYPTOPHAN

N ALPHA-9-FLUORENYLMETHYLOXYCARBONYL-N(IN)-T-BUTOXYCARBONYL-L-TRYPTOPHAN

Fmoc-Trp(Boc)-OH ,98%

FMoc-Trp(Boc)-OH N-α-FMoc-N-in-Boc-L-tryptophan

1-Boc-N^a-FMoc-L-tryptophan, 97%

Nα-[(9H-Fluoren-9-ylMethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan

1-Boc-N-FMoc-L-tryptophan, 97%

N1-Boc-Nalpha-Fmoc-L-tryptophan Fmoc-Trp(Boc)-OH

Fmoc-Trp(Boc)-OH >=97.0% (HPLC)

(2S)-3-{1-[(tert-Butoxy)carbonyl]-1H-indol-3-yl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

Nα-Fmoc-Nin-Boc-L-tryptophan≥ 98% (HPLC)

(9H-Fluoren-9-yl)MethOxy]Carbonyl Trp(Boc)-OH

N-Fmoc-NIn-Boc-L-trp

Fmoc-Trp(Boc)-OH (contains 8% solvents)

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid

(2R)-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

Fmoc-Trp(Boc)-OH, 97.0%

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoicacid

N(in)-Boc-Nα-Fmoc-L-tryptophan

Nα-Fmoc-N(in)-Boc-L-tryptophan

N-tert-Butoxycarbonyl-N-9-fluorenylmethoxycarbonyl-L-tryptophan

N-α-Fmoc-N-in-Boc-L-tryptophan

FMOC-TRP(BOC)-OH 99+%

N-ALPHA-(9-FLUOROENYLMETHYLOXYCARBONYL)-N-IN-T-BUTYLOXYCARBONYL-L-TRYPTOPHAN

FMOC-L-TRYPTOPHANE

N (in) -Boc- N α -Fmoc- L -tryptophan

Nin-tert-Butoxycarbonyl-NALPHA-9-fluorenylmethoxycarbonyl-L-tryptophan

FMOC-N-BOC-L-TRYPTOPHAN (FMOC-L-TRP(BOC)-OH)

1-[(TERT-BUTYL)CARBONYL]-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-TRYPTOPHAN

Nα-Fmoc-N(in)-Boc-L-tryptophan, N(in)-Boc-Nα-Fmoc-L-tryptophan

N1-Boc-Nalpha-Fmoc-L-tryptophan

Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-IN-TERT-BUTYLOXYCARBONYL-L-TRYPTOPHAN

N(IN)-BOC-N-ALPHA-FMOC-L-TRYPTOPHAN

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan&gt

FMOC-TRP(BOC)-OH 25 G

FMOC-TRP(BOC)-OH 100 G

N1-Boc-NaL

pha-Fmoc-L

L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

N(α)-fmoc-N(in)-boc-L-tryptophan