ChemicalBook > CAS DataBase List > Balsalazide disodium

Balsalazide disodium

Product Name
Balsalazide disodium
CAS No.
150399-21-6
Chemical Name
Balsalazide disodium
Synonyms
BALOFLOXACIN;BALSALAZIDE SODIUM;Balsazide Disodium;BALSALZIDE DISODIUM;Balsalazie DisodiuM;Balsalazide disodium;BALSALAZIDEDISODOUMSALT;Balsalazide Disodium USP;Balsalazide (sodium hydrate);Balsalazide Disodium Hydrate
CBNumber
CB3367030
Molecular Formula
C17H18N3NaO7
Formula Weight
399.33
MOL File
150399-21-6.mol
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Balsalazide disodium Property

Melting point:
>195°C (dec.)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
Yellow
Merck 
14,945
InChIKey
XDCNKOBSQURQOZ-MVIJUDHYSA-L
SMILES
C(C1C(=CC=C(/N=N/C2C=CC(C(=O)NCCC(=O)O)=CC=2)C=1)O)(=O)O.[NaH].O
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Safety

HS Code 
2927000000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1048255
Product name
Balsalazide disodium
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200MG
Price
$450
Updated
2025/07/31
TCI Chemical
Product number
B4121
Product name
Balsalazide Disodium Salt Dihydrate
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$112
Updated
2025/07/31
TCI Chemical
Product number
B4121
Product name
Balsalazide Disodium Salt Dihydrate
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$376
Updated
2024/03/01
TRC
Product number
B116295
Product name
BalsalazideDisodiumDihydrate
Packaging
10mg
Price
$130
Updated
2021/12/16
TRC
Product number
B116295
Product name
BalsalazideDisodiumDihydrate
Packaging
25mg
Price
$250
Updated
2021/12/16
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Balsalazide disodium Chemical Properties,Usage,Production

Uses

antiinflammatory

Uses

Balsalazide Disodium Dihydrate is an analogue of Sulfasalazine (S699084), A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-β-alanine. Anti-inflammatory (gastrointestinal).

Definition

ChEBI: The dihydrate of the disodium salt of balsalazide. A prodrug, releasing the anti-inflammatory 5-aminosalicylic acid (mesalazine) in the large intestine, it is used in the treatment of ulcerative colitis.

Indications

Balsalazide disodium is delivered intact to the colon, where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, the therapeutically active portion of the molecule, and 4-aminobenzoyl-β-alanine; the latter compound is only minimally absorbed and is largely inert.

brand name

Colazal (Salix).

in vivo

At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group[1]. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug[2].

IC 50

IL-6; IL-1; STAT3

Balsalazide disodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Balsalazide disodium Suppliers

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View Lastest Price from Balsalazide disodium manufacturers

Sinoway Industrial co., ltd.
Product
Balsalazide disodium 150399-21-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2025-01-02
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Balsalazide disodium 150399-21-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-12-17
Career Henan Chemical Co
Product
Balsalazide disodium 150399-21-6
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
200KG
Release date
2019-08-30

150399-21-6, Balsalazide disodiumRelated Search:

Sodium Phosphate, Dibasic LACTOSE, MONOHYDRATE Pemetrexed Disodium Fructose sodium diphosphate PHENYL VALERATE PYRAZOPHOS Sulfasalazine CHLOROPHOSPHONAZO III Ethylenediaminetetraacetic acid disodium salt Diphenyl ether CARBONYL SULFIDE Disodium edetate dihydrate ERBIUM (III) 2,4-PENTANEDIONATE Phenyl salicylate PHENYL RESIN BALSALAZIDE DISODIUM SALT Phenylacetic acid BALOFLOXACIN,BALOFLOXACIN 98.5% EXTRA PURE,BALOFLOXACIN 98.5%,Balofloxacin425.46

  • BALSALAZIDE DISODIUM SALT DIHYDRATE
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  • BALSALAZIDE SODIUM
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  • BALSALAZIDEDISODOUMSALT
  • (E)-5-[[4-[[(2-Carboxyethyl)amino]-carbonyl]phenyl]azo-2-hydroxy-benzoic acid disodium salt
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  • Balsalazide (sodium hydrate)
  • Balsalazide Disodium Hydrate
  • disodium 3-[[4-[(2-carboxylatoethylamino)-oxomethyl]phenyl]hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienecarboxylate dihydrate
  • Balsalazide Disodium Salt Dihydrate&gt
  • 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic Acid Disodium Salt
  • Balsalazide disodium dihydrateQ: What is Balsalazide disodium dihydrate Q: What is the CAS Number of Balsalazide disodium dihydrate Q: What is the storage condition of Balsalazide disodium dihydrate Q: What are the applications of Balsalazide disodium dihydrate
  • Balsalazide Disodium (1048255)
  • 5-[(1E)-2-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]diazenyl]-2-hydroxy-Benzoic acid sodium salt hydrate (1:2:2)
  • Balsalazide Disodium Salt Dihydrate, ≥ 98.0%
  • Balsalazide Disodium USP
  • Sodium (E)-5-((4-((2-carboxylatoethyl)carbamoyl)phenyl)diazenyl)-2-hydroxybenzoate dihydrate
  • Balsalazide sodium hydrate, 10 mM in DMSO
  • 150399-21-6
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  • 0399-21-6
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  • C17H17N3Na2O8
  • C17H15N3O62H2O2Na
  • COLAZAL
  • Intermediates