1-METHANESULFONYL-PIPERAZINE

Product Name: 1-METHANESULFONYL-PIPERAZINE
CAS No.: 55276-43-2
Chemical Name: 1-METHANESULFONYL-PIPERAZINE
Synonyms: AKOS B003961;1-mesylpiperazine;CHEMBRDG-BB 3003961;ART-CHEM-BB B003961;ART-CHEM-BB B022241;IFLAB-BB F2124-0764;TIMTEC-BB SBB007001;1-METHYLSULPHONYLPIPERAZINE;1-METHANESULFONYL-PIPERAZINE;1-(METHYLSULFONYL)PIPERAZINE
CBNumber: CB3368178
Molecular Formula: C5H12N2O2S
Formula Weight: 164.23
MOL File: 55276-43-2.mol

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1-METHANESULFONYL-PIPERAZINE Property

Melting point:: 99 °C
Boiling point:: 280.6±50.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 7.78±0.10(Predicted)
form: Solid
color: White to Almost white
Water Solubility: Slightly soluble in water.
CAS DataBase Reference: 55276-43-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-36/37/39-24/25-23
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2437
Product name: 1-(Methylsulfonyl)piperazine
Purity: >98.0%(GC)
Packaging: 5g
Price: $80
Updated: 2025/07/31

TRC

Product number: B486145
Product name: 1-(Methylsulfonyl)piperazine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR0841
Product name: 1-(Methylsulphonyl)piperazine
Purity: 98+%
Packaging: 5g
Price: $80
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK192210
Product name: 1-Methanesulfonyl-piperazine
Purity: 98%
Packaging: 1g
Price: $80
Updated: 2021/12/16

Matrix Scientific

Product number: 028784
Product name: 1-(Methylsulfonyl)piperazine
Packaging: 25g
Price: $114
Updated: 2021/12/16

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1-METHANESULFONYL-PIPERAZINE Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

1-(Methylsulfonyl)piperazine is employed as a intermediate for pharmaceutical and chemical research.

Synthesis

164331-38-8

55276-43-2

Step 2: Synthesis of 1-(methylsulfonyl)piperazine A mixture of tert-butyl 4-(methylsulfonyl)piperazine-1-carboxylate (1.0 g, 3.79 mmol) with trifluoroacetic acid (TFA, 0.86 g, 7.58 mmol) in dichloromethane (CH2Cl2, 10 mL) was stirred for 2 hours at room temperature. After completion of the reaction, the mixture was concentrated under reduced pressure to afford 1-(methylsulfonyl)piperazine as a yellow oil (0.5 g, 80.52% yield). The product was characterized by 1H NMR (400 MHz, CD3OD): δ 3.50-3.47 (m, 4H), 3.33-3.28 (m, 4H), 2.92 (s, 3H); ESI-MS m/z: 165 ([M + H]+).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 1, p. 375 - 379
[2] Patent: WO2010/141538, 2010, A1. Location in patent: Page/Page column 23
[3] Patent: WO2004/43950, 2004, A1. Location in patent: Page 152
[4] Patent: WO2005/51957, 2005, A1. Location in patent: Page/Page column 61-62
[5] Patent: WO2004/85425, 2004, A1. Location in patent: Page 98

1-METHANESULFONYL-PIPERAZINE Preparation Products And Raw materials

Raw materials

Di-tert-butyl dicarbonate Trifluoroacetic acid Triethylamine Chloroform Piperazine Ethyl chloroformate Methanesulfonyl chloride Isopropyl acetate Diethyl ether Ethyl acetate Dichloromethane Methanol Sodium hydroxide Isopropyl alcohol Sodium carbonate

Preparation Products

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1-METHANESULFONYL-PIPERAZINE Suppliers

Americas 1 Canada 1 China 122 Europe 1 France 1 Germany 7 India 8 Japan 2 Russia 2 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 9 United States 35 Global 194

Shanghai Pleikon Chemical Technology Co., Ltd

Tel: 021-021-54321516 17717324060
Email: 2719672468@qq.com
Country: China
ProdList: 1880
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
Advantage: 55

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
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Energy Chemical

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Fax: 021-58436166
Email: sales8178@energy-chemical.com
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Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
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Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
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Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
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View Lastest Price from 1-METHANESULFONYL-PIPERAZINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 1-METHANESULFONYL-PIPERAZINE 55276-43-2
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-27

Hebei Zhanyao Biotechnology Co. Ltd

Product: 1-METHANESULFONYL-PIPERAZINE 55276-43-2
Price: US $10.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-11-04

Hebei Zhanyao Biotechnology Co. Ltd

Product: 1-METHANESULFONYL-PIPERAZINE 55276-43-2
Price: US $10.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-11-05

55276-43-2, 1-METHANESULFONYL-PIPERAZINERelated Search:

1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE H-7 DIHYDROCHLORIDE 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE 1-(8-CHLORO-5-ISOQUINOLINE-SULFONYL)PIPERAZINE 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE 1-METHANESULFONYL-PIPERAZINE HYDROCHLORIDE 1-(Methanesulfonyl)-piperazine / 1-(Methanesulfonyl)-piperazine monohydrochloride N,N'-BIS(P-TOLUENESULFONYL)PIPERAZINE 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4-((1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRROL-2-YL)SULFONYL)PIPERAZINE 7-(4-[(4-CHLOROPHENYL)SULFONYL]PIPERAZINO)-2,4-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDINE 2-NITRO-1-((4-(5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL)SULFONYL)BENZENE 1-((4-(3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL)SULFONYL)-2-NITROBENZENE ETHYL 2-(1-[(4-CHLOROPHENYL)SULFONYL]-3-OXO-2-PIPERAZINYL)ACETATE 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4-[(4-METHYLPHENYL)SULFONYL]PIPERAZINE N,1-DIMETHYL-6-[4-(METHYLSULFONYL)PIPERAZINO]-3,5-DINITRO-1,4-DIHYDRO-2-PYRIDINAMINE N,N'-BIS(BENZENESULFONYL)PIPERAZINE N,N'-BIS(O-TOLUENESULFONYL)PIPERAZINE

1-METHANESULFONYL-PIPERAZINE

1-N-METHANESULFONYLPIPERAZINE

1-(METHYLSULFONYL)PIPERAZINE

1-METHYLSULPHONYLPIPERAZINE

AKOS B003961

CHEMBRDG-BB 3003961

1-METHANESULFONYL-PIPERAZINE >98%

1-(Methylsulphonyl)piperazine 98+%

IFLAB-BB F2124-0764

ART-CHEM-BB B022241

ART-CHEM-BB B003961

TIMTEC-BB SBB007001

1-(methylsulfonyl)piperazine(SALTDATA: FREE)

Methyl (piperazin-1-yl) sulphone

Piperazine, 1-(methylsulfonyl)-

1-mesylpiperazine

1-(Methylsulfonyl)piperazine&gt

1-(Methylsulfonyl)piperazine,97%

1-Methanesulfonyl-piperzaine

1-Methanesulfonyl piperizine

55276-43-2

C5H12N2O2SHCl

piperazines

Amines and Anilines

Heterocycles

Buildingblock