1-METHANESULFONYL-PIPERAZINE
- Product Name
- 1-METHANESULFONYL-PIPERAZINE
- CAS No.
- 55276-43-2
- Chemical Name
- 1-METHANESULFONYL-PIPERAZINE
- Synonyms
- AKOS B003961;1-mesylpiperazine;CHEMBRDG-BB 3003961;ART-CHEM-BB B003961;ART-CHEM-BB B022241;IFLAB-BB F2124-0764;TIMTEC-BB SBB007001;1-METHYLSULPHONYLPIPERAZINE;1-METHANESULFONYL-PIPERAZINE;1-(METHYLSULFONYL)PIPERAZINE
- CBNumber
- CB3368178
- Molecular Formula
- C5H12N2O2S
- Formula Weight
- 164.23
- MOL File
- 55276-43-2.mol
1-METHANESULFONYL-PIPERAZINE Property
- Melting point:
- 99 °C
- Boiling point:
- 280.6±50.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 7.78±0.10(Predicted)
- form
- Solid
- color
- White to Almost white
- Water Solubility
- Slightly soluble in water.
- CAS DataBase Reference
- 55276-43-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36/37/39-24/25-23
- HazardClass
- IRRITANT
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M2437
- Product name
- 1-(Methylsulfonyl)piperazine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $80
- Updated
- 2025/07/31
- Product number
- B486145
- Product name
- 1-(Methylsulfonyl)piperazine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J50712
- Product name
- 1-(Methylsulfonyl)piperazine
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- B042
- Product name
- 1-(Methylsulfonyl)piperazine
- Packaging
- 1g
- Price
- $21
- Updated
- 2021/12/16
- Product number
- OR0841
- Product name
- 1-(Methylsulphonyl)piperazine
- Purity
- 98+%
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
1-METHANESULFONYL-PIPERAZINE Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
1-(Methylsulfonyl)piperazine is employed as a intermediate for pharmaceutical and chemical research.
Synthesis
164331-38-8
55276-43-2
Step 2: Synthesis of 1-(methylsulfonyl)piperazine A mixture of tert-butyl 4-(methylsulfonyl)piperazine-1-carboxylate (1.0 g, 3.79 mmol) with trifluoroacetic acid (TFA, 0.86 g, 7.58 mmol) in dichloromethane (CH2Cl2, 10 mL) was stirred for 2 hours at room temperature. After completion of the reaction, the mixture was concentrated under reduced pressure to afford 1-(methylsulfonyl)piperazine as a yellow oil (0.5 g, 80.52% yield). The product was characterized by 1H NMR (400 MHz, CD3OD): δ 3.50-3.47 (m, 4H), 3.33-3.28 (m, 4H), 2.92 (s, 3H); ESI-MS m/z: 165 ([M + H]+).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 1, p. 375 - 379
[2] Patent: WO2010/141538, 2010, A1. Location in patent: Page/Page column 23
[3] Patent: WO2004/43950, 2004, A1. Location in patent: Page 152
[4] Patent: WO2005/51957, 2005, A1. Location in patent: Page/Page column 61-62
[5] Patent: WO2004/85425, 2004, A1. Location in patent: Page 98
1-METHANESULFONYL-PIPERAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-METHANESULFONYL-PIPERAZINE manufacturers
- Product
- 1-METHANESULFONYL-PIPERAZINE 55276-43-2
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2020-04-27
- Product
- 1-METHANESULFONYL-PIPERAZINE 55276-43-2
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-11-04
- Product
- 1-METHANESULFONYL-PIPERAZINE 55276-43-2
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-11-05