Formamidine acetate

Product Name: Formamidine acetate
CAS No.: 3473-63-0
Chemical Name: Formamidine acetate
Synonyms: FAA;forMiMidaMide acetate;Formamidinium acetate;FORMAMIDINE ACETATE SALT;IMINOFORMAMIDE ACETATE;Methanimidamide(9CI);Methanimidamide monoacetate;FORMAMIDINE ACETIC ACID SALT;CB3408896;ormamidine acetate
CBNumber: CB3408896
Molecular Formula: C3H8N2O2
Formula Weight: 104.11
MOL File: 3473-63-0.mol

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Formamidine acetate Property

Melting point:: 158-161 °C (dec.)(lit.)
Density: 1.124
storage temp.: Store below +30°C.
solubility: 832g/l
form: Liquid
color: Clear colorless to light yellow
PH: 8 (400g/l, H2O, 20℃)
Water Solubility: 832 g/L (21 ºC)
Sensitive: Hygroscopic
BRN: 3563488
InChI: InChI=1S/C2H4O2.CH4N2/c1-2(3)4;2-1-3/h1H3,(H,3,4);1H,(H3,2,3)
InChIKey: XPOLVIIHTDKJRY-UHFFFAOYSA-N
SMILES: C(C)(=O)O.C(=N)N
CAS DataBase Reference: 3473-63-0(CAS DataBase Reference)
EPA Substance Registry System: Methanimidamide, monoacetate (3473-63-0)

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Safety

Hazard Codes: Xi
Risk Statements: 43-36/37/38
Safety Statements: 36/37-37/39-26-36/37/39-27
WGK Germany: 2
F: 3-9-21
Autoignition Temperature: 565 °C
TSCA: Yes
HS Code: 29252000
Toxicity: LD50 orally in Rabbit: 2510 mg/kg LD50 dermal Rat > 2000 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F15803
Product name: Formamidine acetate salt
Purity: 99%
Packaging: 100g
Price: $61.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: F15803
Product name: Formamidine acetate salt
Purity: 99%
Packaging: 500g
Price: $229
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.14653
Product name: Formamidine acetate
Purity: for synthesis
Packaging: 100g
Price: $123
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.14653
Product name: Formamidine acetate
Purity: for synthesis
Packaging: 500g
Price: $333
Updated: 2024/03/01

TCI Chemical

Product number: F0154
Product name: Formamidine Acetate
Purity: >98.0%(T)
Packaging: 25g
Price: $22
Updated: 2024/03/01

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Formamidine acetate Chemical Properties,Usage,Production

Description

Formamidine acetate is an anti-tuberculosis drug that belongs to the class of aminoglycosides. It has been shown to have a potent cytotoxic effect on malignant brain cells in vitro. It inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. It also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Chemical Properties

white to light yellow crystalline powder

Uses

Formamidine acetate is used as an intermediate in the synthesis of active pharmaceutical ingredients. It is also used as a condensing agent for the preparation of pyrimidine and imidazole heterocycles.

Uses

Formamidine acetate salt is widely used in the preparation of formamidinium lead triiodide (FAPbI₃) perovskites for perovskite solar cells. It is also used in the synthesis of formamidinium lead bromide nanocrystals for use as emitters in display applications.

Purification Methods

Unlike the hydrochloride, the acetate salt is not hygroscopic. It is recrystallised from a small volume of acetic acid, by addition of EtOH and the crystals are washed with EtOH then Et2O and dried in a vacuum. [Taylor et al. Org Synth 46 39 1966, Beilstein 2 IV 82.]

Formamidine acetate Preparation Products And Raw materials

Raw materials

Preparation Products

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine 5-METHOXY-QUINAZOLIN-4-YLAMINE 4-HYDROXY-5-NITROPYRIMIDINE 4,6-DIHYDROXY-5-METHYLPYRIMIDINE 4-Hydroxy-6-(trifluoromethyl)pyrimidine 4-chloro-5-fluoropyrimidine 4-Hydroxy-5-fluorpyrimidine 4-AMINOPYRIMIDINE-5-CARBONITRILE 6-CHLOROQUINAZOLIN-4-AMINE 4,6-Dimethylpyrimidine-5-carboxylic acid 4-Amino-6-methylpyrimidine-5-carbonitrile ,97% 4-Imidazolemethanol hydrochloride 4-AMINOPYRIMIDINE-5-CARBOXAMIDE

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Formamidine acetate Suppliers

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View Lastest Price from Formamidine acetate manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: Formamidine acetate 3473-63-0
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 1000
Release date: 2024-05-17

Shanghai UCHEM Inc.

Product: Formamidine acetate 3473-63-0
Price: US $45.00-230.00/g
Min. Order: 25g
Purity: 0.98
Supply Ability: 100kg
Release date: 2023-10-25

Hebei Weibang Biotechnology Co., Ltd

Product: Formamidine acetate 3473-63-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

3473-63-0, Formamidine acetateRelated Search:

Vinyl acetate FORMAMIDINE HYDROCHLORIDE Amitraz Methyl acetate Ethyl acetate N-2,4-DIMETHYLPHENYL-N'-METHYLFORMAMIDINE Medroxyprogesterone Acetate Butyl acetate Sodium acetate Tocopheryl acetate Glatiramer acetate BENZAMIDINE Methoxyacetic acid POLY(VINYL ACETATE) Linalyl acetate Cinnamyl acetate N-DECYL ACETATE N-ALPHA-BENZOYL-L-ARGININE

Methanimidamide(9CI)

ormamidine acetate

IMINOFORMAMIDE ACETATE

FORMAMIDINE ACETATE SALT

FORMAMIDINE,ACETIC ACID

FORMAMIDINE ACETIC ACID SALT

FORMAMIDINE ACETATE

FAA

Methanimidamideacetate

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formamidine monoacetate

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Formamidinmonoacetat

Methanimidamide monoacetate

Acetic acid·formamidine

ForMaMidine acetate salt 99%

Acetic acid arMour aMidine

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ForMaMidine acetate, 99% 100GR

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FORMAMIDINE ACETATE FOR SYNTHESIS

FormamidineAcetate&gt

FormaFormamidine acetatemidine acetate

Acetic acid armour am

High quality Formamidine acetate CAS 3473-63-0

methanimidoylazanium

Formamidine acetate (6CI)

CB3408896

3473-63-0

40730-91-7

HNCHNH2CH3COOH

CH4N2CH3COOH

CH4N2C2H4O2

C2H4O2CH4N2

Imines/Amidines

Nitrogen Compounds

Organic Building Blocks

Building Blocks

API

Pharmaceutical Intermediates

bc0001

3473-63-0