5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Product Name: 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
CAS No.: 22276-95-5
Chemical Name: 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
Synonyms: 7-BroMo-6-chloro-7-deazapurine;5-Bromo-4-chloro-7H-pyrro...;5-broMo-4-chloro-7H-pyrrolo[2;5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine;4-chloro-5-bromo-7H-pyrrolo[2,3-d]pyrimidine;5-bromo-4-chloro-1H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-d]pyrimidine, 5-bromo-4-chloro-;5-bromo-4-chloro-7h-pyrrole [2,3-d] pyrimidine;5-Bromo-4-chloro-7H-pyrrolo[2,3-D]pyrimidine ,98%;JR-13964, 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine, 95%
CBNumber: CB01075223
Molecular Formula: C6H3BrClN3
Formula Weight: 232.47
MOL File: 22276-95-5.mol

More

Less

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine Property

Melting point:: 221-225℃
Boiling point:: 221.0±50.0 °C(Predicted)
Density: 2.15±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 9.43±0.20(Predicted)
color: Yellow
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C6H3BrClN3/c7-3-1-9-6-4(3)5(8)10-2-11-6/h1-2H,(H,9,10,11)
InChIKey: OXLMTRZWMHIZBY-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=C2C(Br)=CNC2=N1
CAS DataBase Reference: 22276-95-5

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
RIDADR: 2811
WGK Germany: 3
HazardClass: IRRITANT
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2933599590

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 720194
Product name: 7-Bromo-6-chloro-7-deazapurine
Purity: 95%
Packaging: 1g
Price: $34.5
Updated: 2023/06/20

TRC

Product number: B415485
Product name: 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Usbiological

Product number: 295541
Product name: 7-Bromo-6-chloro-7-deazapurine
Packaging: 5g
Price: $761
Updated: 2021/12/16

AK Scientific

Product number: J97742
Product name: 7-Bromo-6-chloro-7-deazapurine
Packaging: 1g
Price: $10
Updated: 2021/12/16

Oakwood

Product number: 079969
Product name: 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
Purity: 95%
Packaging: 1g
Price: $10
Updated: 2021/12/16

More

Less

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine Chemical Properties,Usage,Production

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Synthesis

4-chloro-7H-pyrrolo[2,3-d]pyrimidine (30 g/0.02 mol) was dissolved in 75 mL of chloroform, followed by added 3.5 g (0.02 mol) of N-bromosuccinamide. The resulting mixture was refluxed for 1 h. After cooling to room temperature, the precipitate was removed by filtration and dried under reduced pressure to afford 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine.

References

[1] Organic Letters, 2003, vol. 5, # 20, p. 3587 - 3590
[2] Synthesis, 2011, # 9, p. 1442 - 1446
[3] Archiv der Pharmazie, 2016, vol. 349, # 5, p. 356 - 362
[4] European Journal of Medicinal Chemistry, 2017, vol. 138, p. 543 - 551
[5] Patent: CN107556318, 2018, A. Location in patent: Paragraph 0101-0103; 0106; 0107

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

N-Bromosuccinimide Formamidine acetate Phosphorus oxitrichloride Sodium iodide Chloroacetaldehyde diethyl acetal Hydrochloric acid Ethyl cyanoacetate

Preparation Products

More

Less

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine Suppliers

Canada 1 China 181 Germany 2 India 4 United Kingdom 2 United States 17 Global 207

Shanghai Arbor Chemical Co., Ltd.

Tel: 021-60451683 15021268886
Fax: +86-21-60451682
Email: sales@arborchemical.com
Country: China
ProdList: 896
Advantage: 55

Hefei Xiuhe Biotechnology Co. Ltd.

Tel: 0551-62887095 13856031416
Email: lism@xhbiotech.com
Country: China
ProdList: 213
Advantage: 58

Shanghai Hansi Chemical Industry Co., Ltd.

Tel: 17717618050
Email: zllg@gh-reagent.com
Country: China
ProdList: 10420
Advantage: 58

SiChuang NanBu Honesty Technology Co., Ltd.

Tel: 0838-5675166 15883665058
Fax: 0838-5675535
Email: nbcxkj@126.com
Country: China
ProdList: 918
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

More

Less

View Lastest Price from 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine manufacturers

Dideu Industries Group Limited

Product: 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine 22276-95-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-01

Career Henan Chemical Co

Product: 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine 22276-95-5
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

22276-95-5, 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidineRelated Search:

5-BROMO-1H-PYRROLO[2 , 3-B]PYRIDIN-2(3H)-ONE 5-Bromo-7-nitroindoline 4-Amino-7H-pyrrolo[2,3-d]pyrimidine 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 2-Thiouracil 2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine Pyrrolo[2,3-d]pyrimidin-4-ol N4-Benzoylcytosine 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE 4-Aminopyrazolo[3,4-d]pyrimidine Chlorobromoisocyanurate 1-Bromo-3-chloro-5,5-dimethylhydantoin 5-BROMO-7-NITRO-1H-INDAZOLE 5-bromo-7H-pyrrolo[2,3-d]pyrimidine Bromochloromethane Difluorochloromethane DEAZAPURINE

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

7-bromo-5-chloro-2,4,9-triazabicyclo[4.3.0]nona-2,4,7,10-tetraene

5-Bromo-4-chloro-7H-pyrrolo[2,3-D]pyrimidine ,98%

5-Bromo-4-chloro-7H-pyrro...

5-broMo-4-chloro-7H-pyrrolo[2

7H-Pyrrolo[2,3-d]pyrimidine, 5-bromo-4-chloro-

7-BroMo-6-chloro-7-deazapurine

5-bromo-4-chloro-1H-pyrrolo[2,3-d]pyrimidine

4-chloro-5-bromo-7H-pyrrolo[2,3-d]pyrimidine

JR-13964, 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine, 95%

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine ISO 9001：2015 REACH

5-bromo-4-chloro-7h-pyrrole [2,3-d] pyrimidine

22276-95-5

Heterocycle-Pyrimidine series

CHIRAL CHEMICALS