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ChemicalBook > CAS DataBase List > N-Boc-N-methylethylenediamine

N-Boc-N-methylethylenediamine

Uses
Product Name
N-Boc-N-methylethylenediamine
CAS No.
121492-06-6
Chemical Name
N-Boc-N-methylethylenediamine
Synonyms
N-Boc-(2-Aminoethyl)-N-methylamine;tert-butyl 2-aminoethyl(methyl)carbamate;BOC,ME-EDA;CAS:121492-06-6;BUTTPARK 90\06-19;BOC-N-METHYLETHYLENEDIAMINE;N-(2-AMinoethyl)-N-Methylca;N-BOC-N-METHYLETHYLENEDIAMINE;1-BOC-1-METHYL-ETHYLENEDIAMINE;N-Boc-N-methyl-1,2-diaminoethane
CBNumber
CB3424935
Molecular Formula
C8H18N2O2
Formula Weight
174.24
MOL File
121492-06-6.mol
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N-Boc-N-methylethylenediamine Property

Melting point:
248-251 °C (decomp)
Boiling point:
79°C/0.4mmHg(lit.)
Density 
0.975 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.447
Flash point:
>100 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
9.44±0.10(Predicted)
form 
Liquid
color 
Clear colorless to pale yellow
BRN 
3588326
InChI
InChI=1S/C8H18N2O2/c1-8(2,3)12-7(11)10(4)6-5-9/h5-6,9H2,1-4H3
InChIKey
QYJVBVKFXDHFPQ-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)N(CCN)C
CAS DataBase Reference
121492-06-6(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
2734
WGK Germany 
3
HazardClass 
8
PackingGroup 
HS Code 
2924190090
Storage Class
8A - Combustible corrosive hazardous materials
Hazard Classifications
Skin Corr. 1B
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
15567
Product name
N-Boc-N-methylethylenediamine
Purity
≥97.0% (GC)
Packaging
1ml
Price
$130
Updated
2023/06/20
Sigma-Aldrich
Product number
15567
Product name
N-Boc-N-methylethylenediamine
Purity
≥97.0% (GC)
Packaging
5ml
Price
$181
Updated
2022/05/15
TCI Chemical
Product number
B4277
Product name
N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine
Purity
>95.0%(GC)(T)
Packaging
1mL
Price
$44
Updated
2025/07/31
TCI Chemical
Product number
B4277
Product name
N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine
Purity
>95.0%(GC)(T)
Packaging
5mL
Price
$132
Updated
2025/07/31
TRC
Product number
A608895
Product name
N-(2-Aminoethyl)-N-methyl-carbamicAcid1,1-DimethylethylEster
Packaging
25g
Price
$875
Updated
2021/12/16
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N-Boc-N-methylethylenediamine Chemical Properties,Usage,Production

Uses

N-Boc-N-methylethylenediamine is a compound useful in organic synthesis and other chemical processes.

Chemical Properties

Liquid

Uses

Mono-protected building block.

reaction suitability

reagent type: cross-linking reagent

Synthesis

24424-99-5

109-81-9

121492-06-6

Step 1: N-methylethylenediamine (11.8 mL, 134.9 mmol) was dissolved in acetonitrile (300 mL) and cooled to -30 °C. Subsequently, triethylamine (TEA, 7.46 mL, 53.9 mmol) was added to this solution, followed by dropwise addition of di-tert-butyl dicarbonate (Boc2O, 9.81 g, 45 mmol) in acetonitrile solution. The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the insoluble material was removed by Celite filtration. The filtrate was purified by silica gel column chromatography (elution gradient: 1:50→1:20→1:10 ethyl acetate/hexane) to afford tert-butyl N-(2-aminoethyl)-N-methylcarbamate (CXVIII) as a yellow oil (5.2 g, 29.9 mmol, 66% yield). The product was confirmed by electrospray ionization mass spectrometry (ESIMS) with molecular formula C8H18N2O2, m/z 175 (M + H).

References

[1] Patent: US2008/318957, 2008, A1. Location in patent: Page/Page column 72; 73
[2] Journal of Medicinal Chemistry, 2000, vol. 43, # 16, p. 3093 - 3102

N-Boc-N-methylethylenediamine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-N-methylethylenediamine Suppliers

Shanghai Chiral Chemicals Inc.
Tel
021-37285021 13472570865
Fax
86-021-51714507
Email
tym7xi@aliyun.com
Country
China
ProdList
297
Advantage
64
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68417696 13962195629
Fax
0512-68417696
Email
minhan.zhao@highfine.com
Country
China
ProdList
475
Advantage
75
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
11997
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
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View Lastest Price from N-Boc-N-methylethylenediamine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
N-Boc-N-methylethylenediamine 121492-06-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-13
Career Henan Chemical Co
Product
N-Boc-N-methylethylenediamine 121492-06-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-09

121492-06-6, N-Boc-N-methylethylenediamineRelated Search:


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