BRYOSTATIN 2

Product Name: BRYOSTATIN 2
CAS No.: 87745-28-6
Chemical Name: BRYOSTATIN 2
Synonyms: BRYO 2;BRYOSTATIN 2;7-O-Deacetylbryostatin 1;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-tetrahydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en-12-yl est;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-Tetrahydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl-(2E,4E)-2,4-octadienoic acid ester;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-tetrahydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl ester, (2E,4E)-
CBNumber: CB3430839
Molecular Formula: C45H66O16
Formula Weight: 863
MOL File: 87745-28-6.mol

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BRYOSTATIN 2 Property

Boiling point:: 957.2±65.0 °C(Predicted)
Density: 1.28±0.1 g/cm3(Predicted)
storage temp.: Store at -20
solubility: Soluble in ethanol
form: film
pka: 11.11±0.70(Predicted)
color: colorless to light yellow
biological source: Bugula neritina (sponge)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1266
Product name: Bryostatin 2
Purity: ≥95% (HPLC)
Packaging: 10μg
Price: $291
Updated: 2025/07/31

TRC

Product number: B750158
Product name: Bryostatin2
Packaging: 25μg
Price: $325
Updated: 2021/12/16

Usbiological

Product number: 254821
Product name: Bryostatin 2
Packaging: 10ug
Price: $565
Updated: 2021/12/16

Apolloscientific

Product number: BIB9351
Product name: Bryostatin2
Packaging: 100μg
Price: $580
Updated: 2021/12/16

ApexBio Technology

Product number: B4942
Product name: Bryostatin2
Packaging: 10ug
Price: $392
Updated: 2021/12/16

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BRYOSTATIN 2 Chemical Properties,Usage,Production

Uses

Bryostatin 2 is a macrocyclic lactone and antagonist of phorbol ester action. It binds to and activates protein kinase C (PKC) creating a transcriptional response similar to phorbol esters.

Definition

ChEBI: Bryostatin 2 is a member of the class of bryostatins that is bryostatin 1 in which the acetoxy group has been replaced by a hydroxy group. It has a role as a protein kinase C agonist, an antineoplastic agent and a marine metabolite. It is a member of bryostatins, a cyclic hemiketal, an enoate ester, a methyl ester, an organic heterotetracyclic compound and a secondary alcohol.

Biological Activity

Bryostatin 2 is potent protein kinase C activator (Ki = 5.9 nM) and an antagonist to phorbol ester tumor promoter 12-0-tetradecanoylphorbol-13-acetate (TPA). Bryostatin 2 exhibits antineoplastic activity against the murine P388 lymphocytic leukemia and human U937 cells.

BRYOSTATIN 2 Preparation Products And Raw materials

Raw materials

Preparation Products

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BRYOSTATIN 2 Suppliers

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87745-28-6, BRYOSTATIN 2Related Search:

Tosylmethyl isocyanide 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE N-BUTYLISOCYANIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Ethyl isocyanoacetate Ferric acetylacetonate SALCOMINE Cupric acetylacetonate TERT-BUTYL ISOCYANIDE Benzyl isocyanide 2,4-PENTANEDIONE, SILVER DERIVATIVE Tris(2,4-pentanedionato)chroMiuM(III) PHENYLSELENOL METHYL ISOCYANOACETATE Aluminum acetylacetonate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) COBALT(II) ACETYLACETONATE

BRYO 2

BRYOSTATIN 2

2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-tetrahydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en-12-yl est

7-O-Deacetylbryostatin 1

(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-Tetrahydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl-(2E,4E)-2,4-octadienoic acid ester

2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-tetrahydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl ester, (2E,4E)-

87745-28-6

C45H66O16

activator