5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

Product Name: 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
CAS No.: 124750-53-4
Chemical Name: 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
Synonyms: TTMB;5-(4;ENTERPRISESTANDARD;Losartan Impurity 9;Olmesartan TTMB impurity;5-[2-(4-methylphenyl)phenyl]-1-trityltetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;5-(4'-Methyl-2-biphenylyl)-1-trityl-1H-tetrazole;Olmesartan Medoxomil Impurity 24（Losartan Impurity 9）
CBNumber: CB3438158
Molecular Formula: C33H26N4
Formula Weight: 478.59
MOL File: 124750-53-4.mol

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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Property

Melting point:: 166-169 °C(Solv: ethyl acetate (141-78-6); dichloromethane (75-09-2))
Boiling point:: 681.6±65.0 °C(Predicted)
Density: 1.13±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly)
form: Solid
pka: 0.30±0.10(Predicted)
color: Off-White
CAS DataBase Reference: 124750-53-4(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TRC

Product number: T889172
Product name: N-Triphenylmethyl-5-[4''-methylbiphenyl-2-yl]tetrazole-d4
Packaging: 10mg
Price: $165
Updated: 2021/12/16

Matrix Scientific

Product number: 093682
Product name: 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole
Purity: 95+%
Packaging: 250mg
Price: $341
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: D62492
Product name: N-Triphenylmethyl-5-[4??-methylbiphenyl-2-yl]tetrazole-d4
Packaging: 10mg
Price: $650
Updated: 2021/12/16

Matrix Scientific

Product number: 093682
Product name: 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole
Purity: 95+%
Packaging: 1g
Price: $756
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: APN0000403
Product name: 5-(4'-METHYLBIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE
Purity: 95.00%
Packaging: 1G
Price: $780.15
Updated: 2021/12/16

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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Chemical Properties,Usage,Production

Chemical Properties

Off-white Solid

Uses

An intermediate in the preparation of labelled Candesartan.

Uses

5-?(4''-?Methyl-?[1,?1''-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole is a reactant in the synthesis of anti-microbial agents.

Synthesis

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole is prepared by the reaction of trityl chloride and 2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl. The specific synthesis steps are as follows:
Dissolve compound 2 (200 g) with stirring at 40°C 700mL of acetone, Aqueous sodium hydroxide solution (40.67 g sodium hydroxide dissolved in 160 mL water) is added, Continue stirring for 1h, A solution of triphenylchloromethane in acetone (270.8 g of triphenylmethyl chloride dissolved in 800 mL of acetone) was initially added dropwise. The solid was added dropwise and gradually evolved into a white turbid liquid. The reaction was monitored by TLC until it was completely filtered off and washed with water to give a solid as intermediate 3. The solid was blow dried at 50°C to give white intermediate 3 (385 g), yield: 95.2%, HPLC: 99.44%.

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Suppliers

Canada 1 China 144 Germany 1 India 8 South Korea 1 United Kingdom 5 United States 15 Global 175

UHN Shanghai Research & Development Co., Ltd.

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Advantage: 58

Energy Chemical

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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XiaoGan ShenYuan ChemPharm co,ltd

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China Langchem Inc.

Tel: 0086-21-58956006
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View Lastest Price from 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Olmesartan Medoxomil Impurity 19 124750-53-4
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98%
Supply Ability: 500mg
Release date: 2024-06-14

Henan Aochuang Chemical Co.,Ltd.

Product: 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-20

Shaanxi Dideu Medichem Co. Ltd

Product: 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-09

124750-53-4, 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazoleRelated Search:

Triphenylmethyl Chloride Trityl candesartan Trityl Irbesartan Trityl candesartan cilexetil 4,4'-Dimethylbiphenyl 2,3,5-Triphenyltetrazolium chloride Silicone oil (high temperature) Chlorodimethylphenylsilane Trityl olmesartan 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 2-Butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-2-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole 4-Phenyltoluene methylphenyl silicone resin Benzyl N-[(2(Trityltetrazol-5-yl-1,1biphenyl-4-yl]-methyl-2-amino-3-methylbutanoate 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole AKOS 91708 AKOS 91707

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

5-[4'-METHYL (1,1'-BIPHENYL)-2-YL]-1-TRIPHENYLMETHYL-TETRAZOLE

5-[2-(4-methylphenyl)phenyl]-1-trityltetrazole

N-(Triphenylmethyl)-5-(4'-Methylbiphenyl-2-Yl-)Tetrazole (Ttmb)

Olmesartan TTMB impurity

1-[2-(diphenylmethyl)phenyl]-5-[2-(4-methylphenyl)phenyl]tetrazole

Losartan Impurity 9

n-(triphenylmethyl)-5-(4'-methylbiphenyl-2-yl-)terazole

N-(TRIPHENYLMETHYL)-5-(4'-METHYLBIPHENYL-2-YL)TETRAZOLE

5-(4'-Methyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-[4''-METHYL (1,1''-BIPHENYL)-2-YL]-1-TRIPHENYLMETHYL-TETRAZOLE 98.5+%

N-TriphenylMethyl-5-[4'-Methylbiphenyl-2-yl]tetrazole-d4

5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole

ENTERPRISESTANDARD

5-(5-Methyl-2-phenylphenyl)-1-(triphenylMethyl)-1H-1,2,3,4-tetrazole

Losartan IMpurity (5-(4'-Methylbiphenyl-2-yl)-1-Trityl-1H-Tetrazole)

TTMB

Olmesartan Medoxomil impurity 8/Olmesartan TTMB Impurity/5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole

1H-Tetrazole, 5-(4'-methyl[1,1'-biphenyl]-2-yl)-1-(triphenylmethyl)-

Losartan Impurity （5-?(4’-?Methyl-?[1,?1’-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole）

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole USP/EP/BP

5-?(4'-?Methyl-?[1,?1'-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole DISCONTINUED. Please see T889170

Olmesartan Medoxomil Impurity 24（Losartan Impurity 9）

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole

5-(4'-Methyl[1,1'-biphenyl]-2-yl)-1-(triphenylmethyl)-1H-tetrazole

5-(4

5-(4'-Methyl-2-biphenylyl)-1-trityl-1H-tetrazole

124750-53-4

C33H22D4N4

C34H29N4

C33H26N4

Biphenyl & Diphenyl ether

API intermediates

Hypertension