4,4'-Dimethoxytrityl chloride
- Product Name
- 4,4'-Dimethoxytrityl chloride
- CAS No.
- 40615-36-9
- Chemical Name
- 4,4'-Dimethoxytrityl chloride
- Synonyms
- DMT;DMT-CL;4,4'-(Chloro(phenyl)Methylene)bis(Methoxybenzene);4,4-DIMETHOXYTRITYL CHLORIDE;Dimethoxy Trityl Chloride;EPB49;DMT-Cl)D;DMTRT-CL;NSC 89782;DMT CHLORIDE
- CBNumber
- CB3442487
- Molecular Formula
- C21H19ClO2
- Formula Weight
- 338.83
- MOL File
- 40615-36-9.mol
4,4'-Dimethoxytrityl chloride Property
- Melting point:
- 123-125 °C
- Boiling point:
- 455.07°C (rough estimate)
- Density
- 1.0887 (rough estimate)
- vapor pressure
- 0Pa at 20℃
- refractive index
- 1.5330 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Powder
- color
- Pink
- Water Solubility
- Soluble in chloroform and methanol. Partially soluble in water
- Sensitive
- Moisture Sensitive
- BRN
- 2471942
- Stability:
- Hygroscopic, Moisture Sensitive
- InChIKey
- JBWYRBLDOOOJEU-UHFFFAOYSA-N
- LogP
- 5.74 at 20℃
- CAS DataBase Reference
- 40615-36-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Methane, chlorobis(p-methoxyphenyl)phenyl-(40615-36-9)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-34
- Safety Statements
- 22-24/25-37/39-26-36-45-36/37/39
- RIDADR
- 3261
- WGK Germany
- 3
- F
- 10-21
- HS Code
- 29093090
- Toxicity
- A hallucinogenic (psychedelic) agent that may catalyze the onset of emotional problems or psychosis in predisposed individuals. DMT is perhaps one of the least studied of the hallucinogens. It causes perceptual alterations and illusions, including changes in touch, taste, and odor. The thinking process is substantially altered; there are hallucinations and loss of contact with reality. There have been no overdose deaths attributed to the direct effects of DMT. The drug is very short-acting, with a duration of effect of about half an hour or less.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 100013
- Product name
- 4,4′-Dimethoxytrityl chloride
- Purity
- 95%
- Packaging
- 5g
- Price
- $61.9
- Updated
- 2024/03/01
- Product number
- 100013
- Product name
- 4,4′-Dimethoxytrityl chloride
- Purity
- 95%
- Packaging
- 25g
- Price
- $173
- Updated
- 2024/03/01
- Product number
- D1612
- Product name
- 4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent]
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $42
- Updated
- 2024/03/01
- Product number
- D1612
- Product name
- 4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent]
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $122
- Updated
- 2024/03/01
- Product number
- A11626
- Product name
- 4,4'-Dimethoxytrityl chloride, 98%
- Packaging
- 5g
- Price
- $46.65
- Updated
- 2024/03/01
4,4'-Dimethoxytrityl chloride Chemical Properties,Usage,Production
Chemical Properties
4,4'-Dimethoxytrityl chloride is pink powder
Uses
4,4'-Dimethoxytrityl chloride is a versatile protecting group for primary alcohols, specially useful in oligonucleotide synthesis
Uses
4,4'-Dimethoxytrityl chloride is used as a protective reagent for oligonucleotide synthesis. It is used for selective protection and deprotection procedures for thiol and hydroxy groups in nucleoside derivatives.
Uses
Hydroxyl protecting group for nucleosides and nucleotides.
Flammability and Explosibility
Not classified
Purification Methods
DMT crystallises from cyclohexane/acetyl chloride as the hydrochloride. Dry it over KOH pellets in a desiccator. When dissolved in *C6H6 and air is blown through, HCl is removed. It crystallises from Et2O. [Baeyer & Villiger Chem Ber 36 2788 1903, Smith et al. J Am Chem Soc 84 430 1962, Smith et al. J Am Chem Soc 85 3821 1963.] Ifit has hydrolysed considerably (see OH in IR), then repeat the crystallisation from cyclohexane/acetyl chloride — excess of AcCl is removed in a vacuum over KOH, then recrystallise it from Et2O. [Beilstein 6 IV 1042.]
4,4'-Dimethoxytrityl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
4,4'-Dimethoxytrityl chloride Suppliers
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- Country
- Belgium
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View Lastest Price from 4,4'-Dimethoxytrityl chloride manufacturers
- Product
- 4,4'-Dimethoxytrityl chloride 40615-36-9
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-11-27
- Product
- 4,4'-Dimethoxytrityl chloride 40615-36-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98
- Supply Ability
- 500
- Release date
- 2024-12-17
- Product
- 4,4'-Dimethoxytrityl chloride 40615-36-9
- Price
- US $128.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 25kg
- Release date
- 2023-12-19