ChemicalBook > CAS DataBase List > 4,4'-Dimethoxytrityl chloride

4,4'-Dimethoxytrityl chloride

Product Name
4,4'-Dimethoxytrityl chloride
CAS No.
40615-36-9
Chemical Name
4,4'-Dimethoxytrityl chloride
Synonyms
DMT;DMT-CL;4,4'-(Chloro(phenyl)Methylene)bis(Methoxybenzene);4,4-DIMETHOXYTRITYL CHLORIDE;Dimethoxy Trityl Chloride;EPB49;DMT-Cl)D;DMTRT-CL;NSC 89782;DMT CHLORIDE
CBNumber
CB3442487
Molecular Formula
C21H19ClO2
Formula Weight
338.83
MOL File
40615-36-9.mol
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4,4'-Dimethoxytrityl chloride Property

Melting point:
123-125 °C
Boiling point:
455.07°C (rough estimate)
Density 
1.0887 (rough estimate)
vapor pressure 
0Pa at 20℃
refractive index 
1.5330 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Powder
color 
Pink
Water Solubility 
Soluble in chloroform and methanol. Partially soluble in water
Sensitive 
Moisture Sensitive
BRN 
2471942
Stability:
Hygroscopic, Moisture Sensitive
InChIKey
JBWYRBLDOOOJEU-UHFFFAOYSA-N
LogP
5.74 at 20℃
CAS DataBase Reference
40615-36-9(CAS DataBase Reference)
NIST Chemistry Reference
Methane, chlorobis(p-methoxyphenyl)phenyl-(40615-36-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-34
Safety Statements 
22-24/25-37/39-26-36-45-36/37/39
RIDADR 
3261
WGK Germany 
3
10-21
HS Code 
29093090
Toxicity
A hallucinogenic (psychedelic) agent that may catalyze the onset of emotional problems or psychosis in predisposed individuals. DMT is perhaps one of the least studied of the hallucinogens. It causes perceptual alterations and illusions, including changes in touch, taste, and odor. The thinking process is substantially altered; there are hallucinations and loss of contact with reality. There have been no overdose deaths attributed to the direct effects of DMT. The drug is very short-acting, with a duration of effect of about half an hour or less.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H335May cause respiratory irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
100013
Product name
4,4′-Dimethoxytrityl chloride
Purity
95%
Packaging
5g
Price
$61.9
Updated
2024/03/01
Sigma-Aldrich
Product number
100013
Product name
4,4′-Dimethoxytrityl chloride
Purity
95%
Packaging
25g
Price
$173
Updated
2024/03/01
TCI Chemical
Product number
D1612
Product name
4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent]
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
D1612
Product name
4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent]
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$122
Updated
2024/03/01
Alfa Aesar
Product number
A11626
Product name
4,4'-Dimethoxytrityl chloride, 98%
Packaging
5g
Price
$46.65
Updated
2024/03/01
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4,4'-Dimethoxytrityl chloride Chemical Properties,Usage,Production

Chemical Properties

4,4'-Dimethoxytrityl chloride is pink powder

Uses

4,4'-Dimethoxytrityl chloride is a versatile protecting group for primary alcohols, specially useful in oligonucleotide synthesis

Uses

4,4'-Dimethoxytrityl chloride is used as a protective reagent for oligonucleotide synthesis. It is used for selective protection and deprotection procedures for thiol and hydroxy groups in nucleoside derivatives.

Uses

Hydroxyl protecting group for nucleosides and nucleotides.

Flammability and Explosibility

Not classified

Purification Methods

DMT crystallises from cyclohexane/acetyl chloride as the hydrochloride. Dry it over KOH pellets in a desiccator. When dissolved in *C6H6 and air is blown through, HCl is removed. It crystallises from Et2O. [Baeyer & Villiger Chem Ber 36 2788 1903, Smith et al. J Am Chem Soc 84 430 1962, Smith et al. J Am Chem Soc 85 3821 1963.] Ifit has hydrolysed considerably (see OH in IR), then repeat the crystallisation from cyclohexane/acetyl chloride — excess of AcCl is removed in a vacuum over KOH, then recrystallise it from Et2O. [Beilstein 6 IV 1042.]

4,4'-Dimethoxytrityl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4'-Dimethoxytrityl chloride Suppliers

GLR Innovations
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View Lastest Price from 4,4'-Dimethoxytrityl chloride manufacturers

INNOBIO PHARM CO.,LTD
Product
4,4’-Dimethoxytriryl Chloride 40615-36-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
20tons
Release date
2025-01-08
Hebei Zhuanglai Chemical Trading Co Ltd
Product
4,4'-Dimethoxytrityl chloride 40615-36-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-27
Wuhan Circle Star Chem-medical Technology Co.,Ltd
Product
4,4'-Dimethoxytrityl chloride 40615-36-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98
Supply Ability
500
Release date
2024-12-17

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