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LUPENONE

Product Name
LUPENONE
CAS No.
1617-70-5
Chemical Name
LUPENONE
Synonyms
LUPENONE;-en-3-one;Lup-20(29);Aids082905;Aids-082905;LUPENONE(RG);18-LUPEN-3-ONE;Lup-20(29)-en-3-one;Lupa-20(30)-ene-3-one;5α-Lup-20(29)-en-3-one
CBNumber
CB3447619
Molecular Formula
C30H48O
Formula Weight
424.7
MOL File
1617-70-5.mol
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LUPENONE Property

Melting point:
165-167°C
Boiling point:
485.7±14.0 °C(Predicted)
Density 
1.115 g/cm3(Temp: 18 °C)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White
LogP
10.400 (est)
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Safety

Hazard Codes 
Xi
HS Code 
29142990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R205265
Product name
LUP-20(29)-EN-3-ONE
Purity
AldrichCPR
Packaging
1MG
Price
$113
Updated
2025/07/31
Usbiological
Product number
453973
Product name
Lupenone
Packaging
2.5mg
Price
$496
Updated
2021/12/16
TRC
Product number
L474840
Product name
Lupenone
Packaging
10mg
Price
$595
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594672
Product name
Lupenone
Packaging
10mg
Price
$513.4
Updated
2021/12/16
Biorbyt Ltd
Product number
orb105776
Product name
Lupenone
Purity
>98%,Standard References Grade
Packaging
20mg
Price
$569.5
Updated
2021/12/16
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LUPENONE Chemical Properties,Usage,Production

Chemical Properties

White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dandelion, bamboo leaves and Adenophora australis.

Uses

Lupenone is a lupane triterpenoid with antioxidant and anticholinesterase activity. It also a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor.

Definition

ChEBI: A natural product found in Cupania cinerea.

in vivo

Lupenone (6, 12, 24 mg/kg/day, gavage for 6 weeks) improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/ CTGF-related fibrosis[2].

Animal Model:Spontaneous type 2 diabetic nephropathy db/db mouse models[1]
Dosage:6, 12, 24 mg/kg
Administration:i.g.
Result:Maintained the fasting blood glucose.
Reduced glycosylated hemoglobin, insulin, and 24 h proteinuria levels.
Regulated changes in biochemical indicators

IC 50

Trypanosoma

LUPENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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LUPENONE Suppliers

China 112 Germany 2 India 2 United Kingdom 3 United States 14 USA 1 Global 134
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from LUPENONE manufacturers

Career Henan Chemical Co
Product
LUPENONE 1617-70-5
Price
US $1.00/KG
Min. Order
1 mg
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

1617-70-5, LUPENONERelated Search:

Madecassoside Madecassic acid dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate roburic acid Terrestrosin K Terrestrosin D Carboxyatractyloside Pachymic acid Betulonicacid LUPENONE Δ1-Lupenone Betulonicacidmethylester N-[3-OXO-LUP-20(29)-EN-28-OYL]AMINOACETIC ACID N-[3-OXO-LUP-20(29)-EN-28-OYL]-3-AMINOPROPIONIC ACID METHYL ESTER N-[3-OXO-LUP-20(29)-EN-28-OYL]AMINOACETIC ACID METHYL ESTER Lupenone I LUPENONE(REAGENT / STANDARD GRADE) N-[3-OXO-LUP-20(29)-EN-28-OYL]-3-AMINOPROPIONIC ACID

  • Aids-082905
  • LUPENONE
  • 18-LUPEN-3-ONE
  • -en-3-one
  • Lup-20(29)
  • LUPENONE(RG)
  • 5α-Lup-20(29)-en-3-one
  • Lup-20(29)-en-3-one
  • Lupa-20(29)-ene-3β-one
  • Lupa-20(30)-ene-3-one
  • (1R,3Ar,4S,5ar,5br,7ar,11ar,11br,13ar,13br)-1-isopropenyl-3A,5A,5B,8,8,11A-hexamethyl-eicosahydro-cyclopenta[A]chrysen-9-one
  • Aids082905
  • (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysen-9-one
  • (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-Hexamethyl-1-(prop-1-en-2-yl)icosahydro-9H-cyclopenta[a]chrysen-9-one
  • 1617-70-5
  • 1657-70-5
  • Building block