DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID

ChemicalBook > CAS DataBase List > DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID

DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID

Product Name: DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID
CAS No.: 76326-31-3
Chemical Name: DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID
Synonyms: APV;AP-5;DL-AP5;DL-APV;C13734;(±)-2-AP5;5-phosphono-L-norvaline;Norvaline, 5-phosphono-;5-PHOSPHONO-DL-NORVALINE;2-amino-5-phosphopentanoicacid
CBNumber: CB3448803
Molecular Formula: C5H12NO5P
Formula Weight: 197.13
MOL File: 76326-31-3.mol

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DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Property

Melting point:: 238-245oC
Boiling point:: 482.1±55.0 °C(Predicted)
Density: 1.529±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: NH₄OH 1 M: 50 mg/mL, clear, colorless
form: solid
pka: 2.46±0.10(Predicted)
color: white
Water Solubility: Soluble to 10 mM in water and to 100 mM in 1eq. NaOH
BRN: 2446389
CAS DataBase Reference: 76326-31-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A5282
Product name: DL-2-Amino-5-phosphonopentanoic acid
Purity: solid
Packaging: 10mg
Price: $110
Updated: 2024/03/01

Sigma-Aldrich

Product number: A5282
Product name: DL-2-Amino-5-phosphonopentanoic acid
Purity: solid
Packaging: 25mg
Price: $298
Updated: 2024/03/01

Cayman Chemical

Product number: 14540
Product name: DL-AP5
Purity: ≥95%
Packaging: 5mg
Price: $47
Updated: 2024/03/01

Cayman Chemical

Product number: 14540
Product name: DL-AP5
Purity: ≥95%
Packaging: 10mg
Price: $73
Updated: 2024/03/01

Sigma-Aldrich

Product number: A5282
Product name: DL-2-Amino-5-phosphonopentanoic acid
Purity: solid
Packaging: 50mg
Price: $477
Updated: 2024/03/01

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DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Chemical Properties,Usage,Production

Uses

DL-2-Amino-5-phosphonopentanoic acid has been used:

in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses
used in growth medium for inhibition of electrical activity in the neuronal network
used to isolate N-methyl-D-aspartate receptors (NMDAR) or α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this product
used in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)

Definition

ChEBI: The 5-phosphono derivative of 2-aminopentanoic acid; acts as an N-methyl-D-aspartate receptor antagonist.

Biological Activity

Potent NMDA antagonist. See separate isomers (D-(-)-2-Amino-5-phosphonopentanoic acid and L-(+)-2-Amino-5-phosphonopentanoic acid ).

Biochem/physiol Actions

Anticonvulsant; potent and selective NMDA receptor antagonist.

storage

Room temperature

DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Suppliers

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76326-31-3, DL-2-AMINO-5-PHOSPHONOPENTANOIC ACIDRelated Search:

2-amino-4-phosphonobutyric acid 5,7-DICHLOROKYNURENIC ACID SODIUM SALT O-Phospho-L-serine Cycloleucine Quinolinic acid Spermidine trihydrochloride (R)-CPP Synthalin sulfate L-701,252 D-AP5 L-AP5 CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID DL-Norvaline DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID LITHIUM SALT,DL-2-Amino-5-phosphonopentanoic acid, AP-5 5-PHOSPHONOPENTANOIC ACID DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID D(-)-2-AMINO-5-PHOSPHONO-PENTANOIC ACID, [4,5-3H]

APV

AP-5

DL-2-AMINO-5-PHOSPHONOVALERIC ACID

DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID

DL-AP5

5-PHOSPHONO-DL-NORVALINE

(+/-)-2-AMINO-5-PHOSPHONO-PENTANOIC ACID

DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID (DL-AP5)

(+/-)-Amino-5-phosphono-pentanoic acid

DL-2-AMINO-5-PHOSPHONOVALERIC ACID (DL-AP5)

5-Phosphono-DL-norvaline, DL-2-Amino-5-phosphonovaleric acid, AP-5, APV

(±)-2-AP5

DL-APV

rac-(2R*)-2-Amino-5-phosphonopentanoic acid

DL-2-Amino-5-phosphonovaleric acid (AP5)

C13734

5-phosphono-L-norvaline

2-amino-5-phosphopentanoicacid

Norvaline, 5-phosphono-

2-amino-5-phosphonopentanoicaci

(S)-2-Amino-5-phosphonopentanoic acid

DL-AP5,2-APV,Retina,Tonic pain,Ganglion cells,Ionotropic glutamate receptors,Inhibitor,inhibit,DL-AP-5,Inhibition,DL AP5,Antinociceptive activity,iGluR,DLAP5

76326-31-3

Ionotropic Glutamate Receptor Modulators

Ion Channels

Ligand-Gated Ion Channels

Substrate Analogs

Enzyme Inhibitors

Enzyme Inhibitors by Type

Enzymes, Inhibitors, and Substrates

Cell Signaling and Neuroscience

Biochemicals and Reagents

BioChemical

Cell Biology

Glutamate

Glutamate receptor