Angiotensin II human acetate
- Product Name
- Angiotensin II human acetate
- CAS No.
- 68521-88-0
- Chemical Name
- Angiotensin II human acetate
- Synonyms
- HYPERTENSIN II;Ang II acetate;DRVYIHPF acetate;ANGIOTENSIN , HUMAN;Angiotensin Ⅱ, human;Angiotensin II xacetate;ANGIOTENSIN II ACETATE SALT;ANGIOTENSIN II ACETATE HUMAN;angiotensin ii human acetate;ANGIOTENSIN II, HUMAN, SYNTHETIC
- CBNumber
- CB3454530
- Molecular Formula
- C52H75N13O14
- Formula Weight
- 1106.25
- MOL File
- 68521-88-0.mol
Angiotensin II human acetate Property
- storage temp.
- −20°C
- solubility
- H2O: 25 mg/mL, clear, colorless
- form
- powder
- color
- orange
Safety
- WGK Germany
- 3
- F
- 3-10
N-Bromosuccinimide Price
- Product number
- 17150
- Product name
- Angiotensin II (human) (acetate)
- Purity
- ≥90%
- Packaging
- 1 mg
- Price
- $25
- Updated
- 2024/03/01
- Product number
- 17150
- Product name
- Angiotensin II (human) (acetate)
- Purity
- ≥90%
- Packaging
- 5 mg
- Price
- $55
- Updated
- 2024/03/01
- Product number
- 17150
- Product name
- Angiotensin II (human) (acetate)
- Purity
- ≥90%
- Packaging
- 10 mg
- Price
- $94
- Updated
- 2024/03/01
- Product number
- 17150
- Product name
- Angiotensin II (human) (acetate)
- Purity
- ≥90%
- Packaging
- 25 mg
- Price
- $176
- Updated
- 2024/03/01
- Product number
- 32970
- Product name
- Angiotensin II acetate salt
- Purity
- ≥ 99% (HPLC)
- Packaging
- 100MG
- Price
- $280
- Updated
- 2021/12/16
Angiotensin II human acetate Chemical Properties,Usage,Production
Uses
Angiotensin II human acetate (Angiotensin II acetate) is a vasoconstrictor that mainly acts on the AT1 receptor. It stimulates sympathetic nervous stimulation and increases aldosterone biosynthesis and renal actions. It also induces the growth of vascular smooth muscle cells. It increases collagen type I and III synthesis in fibroblasts, weakening the vascular wall, myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis.
in vitro
Most of the known actions of Angiotensin II (Ang II) human acetate are mediated by AT1 receptors; the AT2 receptor regulates blood pressure and renal function. Angiotensin II human acetate raises blood pressure (BP) through several actions, the most important ones being vasoconstriction, sympathetic nervous stimulation, increased aldosterone biosynthesis, and renal actions. Other Angiotensin II human acetate actions include induction of growth, cell migration, and mitosis of vascular smooth muscle cells, increased synthesis of collagen type I and III in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. These actions are mediated by type 1 Ang II receptors (AT1). Angiotensin II (1 nM) induces the expression of LOX-1 and VEGF and enhances capillary formation from human coronary endothelial cells in Matrigel assay. Angiotensin II -mediated expression of LOX-1 and VEGF, capillary formation, intracellular reactive oxygen species generation, and phosphorylation of p38 as well as p44/42 mitogen-activated protein kinases were suppressed by anti-LOX-1 antibody, nicotinamide-adenine dinucleotide phosphate oxidase inhibitor apocynin and the Ang II type 1 receptor blocker Losartan, but not by the Ang II type 2 receptor blocker PD123319.
Angiotensin II human acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Angiotensin II human acetate Suppliers
- Tel
- 4401179829988
- Fax
- 4402030 700 369
- customerservice@ascentscientific.co.uk
- Country
- United Kingdom
- ProdList
- 279
- Advantage
- 60
View Lastest Price from Angiotensin II human acetate manufacturers
- Product
- ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT 68521-88-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-03-26
- Product
- Angiotensin II 68521-88-0
- Price
- US $0.00-0.00/Box
- Min. Order
- 1Box
- Purity
- 99
- Supply Ability
- 50000KG/month
- Release date
- 2024-04-26
- Product
- angiotensin 2 68521-88-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10T
- Release date
- 2024-01-11