3-Chlorophenylboronic acid

Product Name: 3-Chlorophenylboronic acid
CAS No.: 63503-60-6
Chemical Name: 3-Chlorophenylboronic acid
Synonyms: 3-CHLOROBENZENEBORONIC ACID;AKOS BRN-0010;RARECHEM AH PB 0179;3-Chlorophenylboroni;3-Chlorophenylboronic;3-CHLOROPHENYLBORNIC ACID;3-Chlorophenylboroic acid;3-CHLOROPHENYLBORONIC ACID;M-CHLOROPHENYLBORONIC ACID;3-Chlorophenylboornic acid
CBNumber: CB3486386
Molecular Formula: C6H6BClO2
Formula Weight: 156.37
MOL File: 63503-60-6.mol

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3-Chlorophenylboronic acid Property

Melting point:: 185-189 °C(lit.)
Boiling point:: 311.4±44.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Methanol
pka: 7.55±0.10(Predicted)
form: Crystalline Powder or Needles
color: White to light yellow-green
Water Solubility: Slightly soluble in water. soluble in ether, tetrahydrofuran,, dimethyl sulfoxide, dimethyl formamide, methanol.
BRN: 2936343
InChI: InChI=1S/C6H6BClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4,9-10H
InChIKey: SDEAGACSNFSZCU-UHFFFAOYSA-N
SMILES: B(C1=CC=CC(Cl)=C1)(O)O
CAS DataBase Reference: 63503-60-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 36-37/39-26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29163990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 417521
Product name: 3-Chlorophenylboronic acid
Purity: ≥95%
Packaging: 1g
Price: $35.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 417521
Product name: 3-Chlorophenylboronic acid
Purity: ≥95%
Packaging: 10g
Price: $202
Updated: 2024/03/01

TCI Chemical

Product number: C1613
Product name: 3-Chlorophenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 5g
Price: $31
Updated: 2024/03/01

TCI Chemical

Product number: C1613
Product name: 3-Chlorophenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 25g
Price: $121
Updated: 2024/03/01

Alfa Aesar

Product number: B24444
Product name: 3-Chlorobenzeneboronic acid, 97%
Packaging: 1g
Price: $20.65
Updated: 2024/03/01

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3-Chlorophenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow-green crystalline powder

Uses

3-Chlorophenylboronic acid is employed as a reactant involved in 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides, Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene, cross-coupling reactions with diazoesters3 or potassium cyanate. It is involved in the synthesis of biarylketones and phthalides and synthesis of inhibitors including PDE4 inhibitors6 among others.

Uses

suzuki reaction

Uses

Reactant involved in:

1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides
Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene
Cross-coupling reactions with diazoesters or potassium cyanate
Synthesis of biarylketones and phthalides
Synthesis of inhibitors including PDE4 inhibitors among others

Synthesis

Using m-dichlorobenzene as the starting material, iodine particles and 1,2-dibromoethane as the initiator reacts with magnesium in an organic solvent to prepare 3-chlorophenyl magnesium chloride. Then, the trimethyl borate is reacted with an organic solvent to prepare 3-chlorophenyl borate dimethyl ester. Finally, the product 3-chlorophenylboronic acid is obtained through hydrolysis, extraction, and crystallization.

Solubility in organics

3-Chlorophenylboronic acid can be dissolved in organic solvents such as N, N-dimethylformamide, ethyl acetate, and dichloromethane. In addition, it also has specific solubility in low-polarity and non-polar organic solvents, but 3-chlorophenylboronic acid has poor solubility in water.

3-Chlorophenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Chlorophenylboronic acid Suppliers

Americas 1 Belgium 3 China 352 Europe 4 France 4 Germany 16 India 34 Italy 1 Japan 5 Russia 1 Switzerland 2 Ukraine 2 United Kingdom 19 United States 70 Global 514

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View Lastest Price from 3-Chlorophenylboronic acid manufacturers

Shanghai UCHEM Inc.

Product: 3-Chlorophenylboronic acid 63503-60-6
Price: US $471.00/kg
Min. Order: 1kg
Purity: 0.98
Supply Ability: 100kg
Release date: 2023-10-26

Henan Fengda Chemical Co., Ltd

Product: 3-Chlorophenylboronic acid 63503-60-6
Price: US $34.00-1.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

Hebei Xinsheng New Material Technology Co., LTD.

Product: 3-Chlorophenylboronic acid 63503-60-6
Price: US $35.00-25.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 Ton
Release date: 2023-10-31

63503-60-6, 3-Chlorophenylboronic acidRelated Search:

Zinc borate 1-Chloro-3-nitrobenzene 1,3-Dichlorobenzene Phenylboronic acid Citric acid Chlorphenamine maleate Hyaluronic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid Ascoric Acid 3,5-Dichlorophenylboronic acid 2,3,4-Trichlorophenylboronic acid 4-FLUORO-3-CHLOROPHENYLBORONIC ACID 2,3-Dichlorophenylboronic acid (3,4,5-Trichlorophenyl)boronic acid 3,4-Dichlorophenylboronic acid 5-CHLORO-2-METHYLPHENYLBORONIC ACID 5-CHLORO-2-ETHOXYPHENYLBORONIC ACID

B-(3-chlorophenyl)-boronic acid

3-Chlorobenzeneboronic acid 98%

3-Chlorophenylboronic

3-Chlorophenylboornic acid

RARECHEM AH PB 0179

3-CHLOROPHENYLBORNIC ACID

3-CHLOROPHENYLBORONIC ACID

3-CHLOROBENZENEBORONIC ACID

3-Chlorophenylboronic acid, CAS 63503-60-6, C6H6BClO2

M-CHLOROPHENYLBORONIC ACID

AKOS BRN-0010

3-CHLOROBENZENEBORONIC ACID / 3-CHLOROPHENYLBORONIC ACID

3-CHLOROPHENYLBORONIC ACID 98%

3-Chlorophenylboronic Acid (contains varying amounts of Anhydride)

3-Chlorophenylboronic acid,97%

3-Chlorophenylboronic acid ,98%

3-Chlorophenylboroni

3-Chlorophenylboronic acid, May contain varying amounts of anhydride, 97%

3-Chlorophenylboronic acid, 97% 5GR

BORONICACID, B-(3-CHLOROPHENYL)-

m-Chlorobenzeneboronic acid

3-Chlorophenylboronic acid, 97%, May contain varying aMounts of anhydride

63503-60-6 3-Chlorophenylboronic acid

3-Chlorophenylboroic acid

63503-60-6

C6H6BO2Cl

BORONIC ACID

Aryl

Boronic Acids and Derivatives

B (Classes of Boron Compounds)

Boronic Acids

Organometallic Reagents

Boronate Ester

Potassium Trifluoroborate

Boronic acids

Aryl

Halogenated

Organoborons

Boronic Acid

B (Classes of Boron Compounds)

Boronic Acids

Boronic Acids and Derivatives

Substituted Boronic Acids

blocks

BoronicAcids

Boronic Acid series