ChemicalBook > CAS DataBase List > D-Threonine

D-Threonine

Product Name
D-Threonine
CAS No.
632-20-2
Chemical Name
D-Threonine
Synonyms
H-D-THR-OH;D-Thr-OH;D-THREONINE, ALLO-FREE;(2R,3S)-2-AMino-3-hydroxybutanoic acid;d-threonin;D-Theronine;D-THREONINE;(r)-threonine;D-Threonine,98%;D-(+)-THREONINE
CBNumber
CB3489099
Molecular Formula
C4H9NO3
Formula Weight
119.12
MOL File
632-20-2.mol
More
Less

D-Threonine Property

Melting point:
274 °C
alpha 
28 º (c=6, water)
Boiling point:
222.38°C (rough estimate)
Density 
1.3126 (rough estimate)
refractive index 
28 ° (C=3, H2O)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: soluble
pka
2.19±0.10(Predicted)
form 
Crystals or Crystalline Powder
color 
White
Water Solubility 
soluble
Merck 
9380
BRN 
1721643
InChIKey
AYFVYJQAPQTCCC-STHAYSLISA-N
CAS DataBase Reference
632-20-2(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-37/39-26
WGK Germany 
3
RTECS 
XO8580000
HS Code 
29225000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T8250
Product name
D-Threonine
Purity
≥98% (TLC)
Packaging
5g
Price
$57.2
Updated
2024/03/01
Sigma-Aldrich
Product number
T8250
Product name
D-Threonine
Purity
≥98% (TLC)
Packaging
25g
Price
$128.4
Updated
2024/03/01
TCI Chemical
Product number
T0228
Product name
D-(+)-Threonine
Purity
>98.0%(T)
Packaging
25g
Price
$97
Updated
2024/03/01
TCI Chemical
Product number
T0228
Product name
D-(+)-Threonine
Purity
>98.0%(T)
Packaging
100g
Price
$287
Updated
2024/03/01
Alfa Aesar
Product number
B21177
Product name
D-Threonine, 99%
Packaging
5g
Price
$34.65
Updated
2024/03/01
More
Less

D-Threonine Chemical Properties,Usage,Production

Description

D-threonine is the D-form of threonine, which is a kind of amino acids. It can be used for the preparation of enantiomerically pure 1, 3-butanediol. It is also used as the intermediate during the preparation of chiral compounds such as antibiotics. D-threonine is an effective chiral pool reagent which contains an extra stereo-center. For example, people has recently used it as the starting material for total synthesis of protected legionaminic acid.

Chemical Properties

white crystalline powder or crystals

Uses

D-Threonine is the unnatural isomer of L-Threonine (T405500) and is known to inhibit growth and cell wall synthesis of Mycobacterium smegmatis. D-Threonine is also used as a synthetic intermediate for the production of chiral antibiotics. It is a steroisomer of the proteinogenic amino acid L-threonine. It has the potential to treat hypostatic leg ulceration.

Definition

ChEBI: D-threonine is an optically active form of threonine having D-configuration. It has a role as a Saccharomyces cerevisiae metabolite. It is a threonine and a D-alpha-amino acid. It is a conjugate base of a D-threoninium. It is a conjugate acid of a D-threoninate. It is an enantiomer of a L-threonine. It is a tautomer of a D-threonine zwitterion.

Application

D-Threonine is a steroisomer of the proteinogenic amino acid L-threonine. D-threonine is an important organic chiral source, mainly used in the fields of chiral drugs, chiral additives, chiral auxiliaries, etc., as a chiral source for chiral synthesis in the pharmaceutical industry. As an optically active organic acid, it has an irreplaceable role in the asymmetric synthesis of certain chiral compounds. It is mainly used to produce new broad-spectrum antibiotics, D-threonine, and threonine protection in peptide synthesis.

benefits

Threonine, pronounced three-uh-neen is one of nine essential amino acids your body needs to function properly. Aiding in maintaining healthy skin, teeth, collagen, elastin, and muscle tissue, it also helps with digestion, metabolism and preventing fat buildup in the liver. Threonine has been used to treat intestinal disorders and indigestion and can be used to help those suffering from depression and anxiety. Recently it has been shown to have promising sleep-promoting effects, which may prove helpful for those who have insomnia and other sleep disorders

General Description

D-Threonine is sweet and toxic in nature.It acts as an inhibitor of L-threonine dehydratase. L-Threonine orientations differ from D-Threonine, specifically in their angles. The L-Threonine tended to self assemble with other L-Threonine molecules while D-Threonine tended to self assemble with other D-Threonine molecules.

References

https://www.alfa.com/zh-cn/catalog/B21177/
Ikemi, Masahisa, et al. "D-Threonine Aldolase and Its Application to D -β-Hydroxy-£-Amino Acid Synthesis." (1992).
Paek SM, et al. "Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis." Molecules 21.7(2016):951.

D-Threonine Preparation Products And Raw materials

Raw materials

Aminoacylase DL-Threonine Chloroacetyl chloride

Preparation Products

L-Isoleucine Cefbuperazone
More
Less

D-Threonine Suppliers

Austria 1 Belgium 1 Canada 1 China 386 Czech Republic 1 Europe 3 France 2 Germany 8 India 10 Japan 10 Poland 1 Switzerland 8 United Kingdom 17 United States 60 USA 1 Global 510
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Abblis Chemicals LLC
Tel
--
Fax
--
Email
info@abblis.com
Country
United States
ProdList
1272
Advantage
0
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
Bachem Americas, Inc.
Tel
--
Fax
--
Email
sales.us@bachem.com
Country
United States
ProdList
161
Advantage
58
Advanced ChemTech (a division of CreoSalus Inc.)
Tel
--
Fax
--
Email
info@advancedchemtech.com
Country
United States
ProdList
177
Advantage
58
Wilshire Technologies, Inc.
Tel
--
Fax
--
Email
info@wilshiretechnologies.com
Country
United States
ProdList
893
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Chiral Management
Tel
--
Fax
--
Email
sales@chiralmanagement.com
Country
United States
ProdList
1332
Advantage
30
AAPPTEC
Tel
--
Fax
--
Email
info@aapptec.com
Country
United States
ProdList
533
Advantage
0
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Glentham Life Sciences Ltd
Tel
--
Fax
--
Email
info@glentham.com
Country
United States
ProdList
2026
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Fisher Scientific
Tel
--
Fax
--
Email
sales@fishersci.com
Country
United States
ProdList
2337
Advantage
86
Advanced Asymmetrics, Inc.
Tel
--
Fax
--
Email
sales@advancedasymmetrics.com
Country
United States
ProdList
521
Advantage
42
AnaSpec, Inc.
Tel
--
Fax
--
Email
service@anaspec.com
Country
United States
ProdList
4871
Advantage
77
Pure Chemistry Scientific Inc
Tel
--
Fax
--
Email
sales@purechems.com
Country
United States
ProdList
2321
Advantage
50
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
srlmarketing@dishnetdsl.net
Country
United States
ProdList
1905
Advantage
64
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
NetQem
Tel
--
Fax
--
Email
sales@netqem.us
Country
United States
ProdList
1641
Advantage
38
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Aroz Technologies, LLC.
Tel
--
Fax
--
Email
sales@aroztech.com
Country
United States
ProdList
1877
Advantage
30
AnsisChem
Tel
--
Fax
--
Country
United States
ProdList
409
Advantage
38
Jupiter Bioscience Limited
Tel
--
Fax
--
Email
vksaipriya@jupiterbioscience.com
Country
United States
ProdList
247
Advantage
68
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
Advantage
38
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
NILE CHEMICALS
Tel
--
Fax
--
Email
nilechem@vsnl.net
Country
United States
ProdList
1369
Advantage
61
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
More
Less

View Lastest Price from D-Threonine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
H-D-Thr-OH 632-20-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98% 99%
Supply Ability
1T+
Release date
2023-09-20
Hebei Zhuanglai Chemical Trading Co Ltd
Product
D-Threonine 632-20-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-13
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
D-Threonine 632-20-2
Price
US $999.00-800.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-22

632-20-2, D-Threonine Related Search:

3-Hydroxybutyric acid Glycine 6-Aminocaproic acid DL-4-Amino-3-hydroxybutyric acid ALTRENOGEST 4-Aminobutyric acid Tris(hydroxymethyl)aminomethane 3-Aminopyridine 3-Aminophenol DL-Threonine FMOC-O-TERT-BUTYL-D-THREONINE,FMOC-O-T-BUTYL-D-THREONINE,FMOC-D-THREONINE(TBU)-OH Z-D-THR-OH (2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid L-Threonine N-(tert-Butoxycarbonyl)-O-benzyl-D-threonine D-beta-Hydroxyvaline BOC-D-THR-OH D-Glucosamic acid

  • D-ALPHA-AMINO-BETA-HYDROXYBUTYRIC ACID
  • D-2-AMINO-3-HYDROXYBUTANOIC ACID
  • D-2-AMINO-3-HYDROXYBUTYRIC ACID
  • H-D-THR-OH
  • D-Threonine,(2R,3S)-2-Amino-3-hydroxybutyric acid, D-α-Amino-β-hydroxybutyric acid
  • (2R,3S)-(+)-Threonine
  • D-β-Hydroxy-2-aMinobutyric acid
  • D-Threonine (D-2-AMino-3-hydroxybutanoic acid)
  • (2R,3S)-2-AMino-3-hydroxybutanoic acid
  • D-Threonine Vetec(TM) reagent grade, >=98%
  • D-Thr-OH
  • D-THREONINE, VETEC
  • D-Threonine,allo-free≥ 99% (Assay)
  • d-threonin
  • D-α-Amino-β-hydroxybutyric acid
  • D-THREONINE, 98% (99% EE/GLC)
  • D-THREONINE, FREE OF ALLOTHREONINE
  • D-Threonine,>99%
  • (2R,3S)-2-Amino-3-hydroxybutyric acid, D-α-Amino-β-hydroxybutyric acid
  • (2R,3S)-(+)-Threonine, (2R,3S)-2-Amino-3-hydroxybutyric acid, D-α-Amino-β-hydroxybutyric acid
  • D-THREONINE extrapure
  • D-Threonine,98%
  • D-Theronine
  • (2R,3S)-2-AMINO-3-HYDROXYBUTYRIC ACID
  • D-(+)-THREONINE
  • D-THREONINE
  • D-THREONINE, ALLO-FREE
  • D-A-AMINO-B-HYDROXYBUTYRIC ACID
  • (r)-threonine
  • D-Threonine USP/EP/BP
  • dextro-threonine
  • D-Threonine-4,4,4-d3Q: What is D-Threonine-4,4,4-d3 Q: What is the CAS Number of D-Threonine-4,4,4-d3
  • D-Threonine (allo-free) extrapure, 99%
  • D-Threonine (9CI, ACI)
  • D-Threonine ( H-D-Thr-OH )
  • 632-20-2
  • 632-60-2
  • 623-20-2
  • Amino Acid Derivatives
  • Specialty Synthesis
  • Threonine
  • Peptide Synthesis
  • amino
  • amino acid
  • Threonine [Thr, T]
  • Amino Acids and Derivatives
  • alpha-Amino Acids
  • Amino Acids
  • Biochemistry
  • Amino Acids
  • PROTECTED AMINO ACID & PEPTIDES
  • Amino ACIDS SERIES
  • Miscellaneous
  • bc0001