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GLIADIN

Product Name
GLIADIN
CAS No.
9007-90-3
Chemical Name
GLIADIN
Synonyms
GLIADIN;gliadins;GLIADINE;from Wheat;Gliadin WHEATGLIADIN;gliadin crude;gliadin from wheat;WHEAT-GAMMA-GLIADIN;GLIADIN FROM WHEAT, POWDER
CBNumber
CB3493924
Molecular Formula
C29H41N7O9
Formula Weight
631.67734
MOL File
9007-90-3.mol
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GLIADIN Property

form 
powder
Merck 
4437
LogP
-2.175 (est)
EPA Substance Registry System
Gliadins (9007-90-3)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G3375
Product name
Gliadin from wheat
Packaging
25g
Price
$348
Updated
2024/03/01
Sigma-Aldrich
Product number
G3375
Product name
Gliadin from wheat
Packaging
100g
Price
$1220
Updated
2024/03/01
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GLIADIN Chemical Properties,Usage,Production

Uses

Chemical synthesis of spinal anesthetics, pharmaceutical preparations.

Uses

Gliadin from wheat has been used in

  • peptic tryptic digestion to study the effect of?in vitro?gliadin challenge on biopsies from celiac disease (CD) patients on gluten-free diet (GFD)
  • to prepare gliadin for antigliadin antibody assay
  • as a standard for the quantification of gliadin levels to the picogram level by flow cytometry

Definition

A prolamin occurring in gluten, the protein of wheat, rye, and other grains. Wheat gliadin has the following composition: 52.7% carbon, 17.7% nitrogen, 21.7% oxygen, 6.9% hydrogen, 1.0% sulfur. It is composed of 18 amino acids, 40% being glutamic acid. In

General Description

Gluten consists of two families of prolamins, known as gliadin and glutenin. Gliadin is a strongly hydrophobic glycoprotein, with a very poor solubility. The gliadins can be further subdivided into α-gliadins, γ-gliadins and ω-gliadins (based on their order of mobility on electrophoresis at low pH).

Biochem/physiol Actions

The gliadins comprise a family of glutamine- and proline-rich monomeric proteins that account for 40-50% of the total protein content of wheat kernels. The alcohol-soluble gliadins aggregate with the alcohol-insoluble glutenins to form gluten, which is responsible for the structure and properties of wheat dough. The gliadins are also involved in the pathogenesis of celiac disease. an autoimmune disease in which human leukocyte antigens DQ2 and DQ8 present gliaden peptides to a subset of T cells inducing the release of proinflammatory cytokines that, in turn, induce degradation of the intestinal mucosal matrix and cell death. B cells are also stimulated to produce gluten-specific and transglutaminase 2 (TG2)-specific antibodies, the latter may result from the presentation of gliadin peptides covalently bound to TG2.

GLIADIN Preparation Products And Raw materials

Raw materials

Preparation Products

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9007-90-3, GLIADINRelated Search:


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  • gliadin from wheat
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  • WHEAT-GAMMA-GLIADIN
  • GLIADIN, FROM WHEAT GLUTEN A PROLAMIN
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