ChemicalBook > CAS DataBase List > (S)-1-CBZ-3-PYRROLIDINOL 95

(S)-1-CBZ-3-PYRROLIDINOL 95

Product Name
(S)-1-CBZ-3-PYRROLIDINOL 95
CAS No.
100858-32-0
Chemical Name
(S)-1-CBZ-3-PYRROLIDINOL 95
Synonyms
CAS:100858-32-0;(S)-1-Cbz-3-pyrrolodonol95;(S)-1-CBZ-3-PYRROLIDINOL 95;(S)-N-Cbz-3-hydroxypyrroline;(S)-(+)-1-Cbz-3-pyrrolidinol;N-Cbz-3(S)-hydroxypyrrolidine;S-1-N-CBZ-3- hydroxy-pyrroline;(S)-1-Cbz-3-hydroxypyrrolidine;(S)-N-CBZ-3-HYDROXYPYRROLIDINE;(S)-(+)-1-Cbz-3-pyrrolidinol 98%
CBNumber
CB3505445
Molecular Formula
C12H15NO3
Formula Weight
221.25
MOL File
100858-32-0.mol
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(S)-1-CBZ-3-PYRROLIDINOL 95 Property

Melting point:
71-77 °C
Boiling point:
370.7±42.0 °C(Predicted)
Density 
1.263±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
14.72±0.20(Predicted)
Appearance
White to off-white Solid
optical activity
[α]20/D +21°, c = 1 in chloroform
InChI
InChI=1S/C12H15NO3/c14-11-6-7-13(8-11)12(15)16-9-10-4-2-1-3-5-10/h1-5,11,14H,6-9H2/t11-/m0/s1
InChIKey
MBLJFGOKYTZKMH-NSHDSACASA-N
SMILES
N1(C(OCC2=CC=CC=C2)=O)CC[C@H](O)C1
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Safety

Hazard Codes 
T
Risk Statements 
25-36/37/38
Safety Statements 
26-36-45-25
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
HazardClass 
6.1
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
654663
Product name
(S)-(+)-1-Cbz-3-pyrrolidinol
Purity
95%
Packaging
1g
Price
$69.2
Updated
2023/01/07
Sigma-Aldrich
Product number
654663
Product name
(S)-(+)-1-Cbz-3-pyrrolidinol
Purity
95%
Packaging
5g
Price
$259
Updated
2023/01/07
TCI Chemical
Product number
C2453
Product name
(S)-1-Carbobenzoxy-3-pyrrolidinol
Purity
>97.0%(GC)
Packaging
1g
Price
$16
Updated
2021/12/16
TCI Chemical
Product number
C2453
Product name
(S)-1-Carbobenzoxy-3-pyrrolidinol
Purity
>97.0%(GC)
Packaging
5g
Price
$48
Updated
2021/12/16
TRC
Product number
B194225
Product name
(S)-(+)-1-Benzyloxycarbonyl-3-hydroxypyrrolidine
Packaging
250mg
Price
$55
Updated
2021/12/16
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(S)-1-CBZ-3-PYRROLIDINOL 95 Chemical Properties,Usage,Production

Chemical Properties

White to off-white crystal powder or solid

Synthesis

130312-02-6

100858-32-0

General procedure for the synthesis of benzyl (S)-3-hydroxypyrrolidine-1-carboxylate using N-Cbz-3-pyrrolidone as starting material: a reaction mixture containing 200 mM substrate, 1 mM NAD+, 5% (v/v) 2-propanol, and 10 mg of the crude enzyme READH was prepared in 1 mL of potassium phosphate buffer (100 mM, pH 7.0) and warmed at 50 °C. For ChKRED20, 40% (v/v) 2-propanol was used and the reaction was carried out at 40°C. The reaction progress was monitored by TLC and the reaction was terminated by extraction with methyl tert-butyl ether (1 mL). The organic phase was dried over anhydrous sodium sulfate and concentrated. Samples were analyzed by chiral HPLC to determine conversion and enantiomeric excess. The final product was purified by silica gel column chromatography and the structure was confirmed by NMR, spin determination and mass spectrometry.

References

[1] Process Biochemistry, 2017, vol. 56, p. 90 - 97

(S)-1-CBZ-3-PYRROLIDINOL 95 Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-1-CBZ-3-PYRROLIDINOL 95 Suppliers

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View Lastest Price from (S)-1-CBZ-3-PYRROLIDINOL 95 manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
(S)-1-CBZ-3-PYRROLIDINOL 95 100858-32-0
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21
Career Henan Chemical Co
Product
(S)-1-CBZ-3-PYRROLIDINOL 95 100858-32-0
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-18

100858-32-0, (S)-1-CBZ-3-PYRROLIDINOL 95Related Search:

(R)-1-CBZ-3-PYRROLIDINOL 5-DIMETHYLAMINO-1-NAPHTHALENESULFONIC ACID HYDRATE N-Cbz-Nortropinone (R)-(-)-3-Pyrrolidinol hydrochloride (R)-3-AMINO-1-CBZ-PYRROLIDINE 3-Pyrrolidinol Benzyl formate N-CBZ-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER 1,4-DIOXA-7-AZA-SPIRO[4.4]NONANE-7-CARBOXYLIC ACID BENZYL ESTER N-(BENZYLOXYCARBONYL)-5-ANTI-ACETOXY-3-EXO-PHENYL-2-AZABICYCLO-[2.1.1]HEXANE Z-CIS-HYP-OH trans-3-Benzylamino-1-Cbz-4-hydroxypyrrolidine (2R,4S)-N-ALPHA-CARBOBENZOXY-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID CIS-ZHPROME (S)-1-CBZ-3-PYRROLIDINOL 95 benzyl (3S)-3-(pyridin-4-yloxy)pyrrolidine-1-carboxylate

  • (S)-(+)-1-Cbz-3-pyrrolidinol 98%
  • (S)-3-hydroxy-1-pyrrolidinecarboxylic acid phenylmethyl ester
  • S-1-N-CBZ-3- hydroxy-pyrroline
  • (S)-1-Cbz-3-pyrrolidinol (S)-1-Carbobenzoxy-3-hydroxypyrrolidine
  • (S)-(-)-1-Benzyloxycarbonyl-3-hydroxypyrrolidine, 95%
  • (S)-(+)-1-Cbz-3-pyrrolidinol, 98%, ee: 98%
  • (S)-(+)-1-Cbz-3-pyrrolidinol, ee: 98%
  • 1-Pyrrolidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester, (3S)-
  • (S)-N-Cbz-3-hydroxypyrroline
  • (S)-N-Cbz-3-hydroxypyrroline,99%e.e.
  • (S)-1-CBZ-3-PYRROLIDINOL 95
  • (S)-N-CBZ-3-HYDROXYPYRROLIDINE
  • N-Cbz-3(S)-hydroxypyrrolidine
  • (S)-1-Benzyloxycarbonyl-3-pyrrolidinol, (S)-1-Carbobenzoxy-3-pyrrolidinol, (S)-N-Z-3-Pyrrolidinol
  • (S)-1-Cbz-3-hydroxypyrrolidine
  • benzyl (3S)-3-hydroxypyrrolidine-1-carboxylate
  • (S)-3-Hydroxy-pyrrolidine-1-carboxylic acid benzyl ester
  • (S)-(+)-1-Cbz-3-pyrrolidinol
  • (S)-1-Carbobenzoxy-3-pyrrolidinol &gt
  • (S)-1-Carbobenzoxy-3-hydroxypyrrolidine
  • (S)-(3-hydroxypyrrolidin-1-yl)(phenyl)methanone
  • Benzyl (S)-3-hydroxypyrrolidine-1-carboxylate
  • Phenylmethyl (3S)-3-hydroxy-1-pyrrolidinecarboxylate
  • (S)-1-Cbz-3-pyrrolodonol95
  • CAS:100858-32-0
  • (<i>S</i>)-(+)-1-Cbz-3-pyrrolidinol
  • (S)-1-Cbz-3-hydroxypyrrolidine - [H12296]
  • 100858-32-0
  • Pyrrole&Pyrrolidine&Pyrroline