4-Bromopyridine-2-carboxylic acid
- Product Name
- 4-Bromopyridine-2-carboxylic acid
- CAS No.
- 30766-03-1
- Chemical Name
- 4-Bromopyridine-2-carboxylic acid
- Synonyms
- 4-BROMOPICOLINIC ACID;4-broMopyriMidine-2-carboxylic acid;AURORA 23242;AKOS BBS-00005794;IFLAB-BB F1926-0016;OTAVA-BB BB7017520050;4-Bromopicolinic acid 97%;Bromopyridinecarboxylicacid;4-BroMopicolinic Acid, 95+%;4-BroMopyridine-2-carboxy...
- CBNumber
- CB3680872
- Molecular Formula
- C6H4BrNO2
- Formula Weight
- 202.01
- MOL File
- 30766-03-1.mol
4-Bromopyridine-2-carboxylic acid Property
- Melting point:
- 172-174
- Boiling point:
- 347.8±27.0 °C(Predicted)
- Density
- 1.813±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Sparingly Soluble in DMSO, Methanol, Water
- pka
- 3.25±0.10(Predicted)
- form
- Solid
- color
- Off-White
- Water Solubility
- Sparingly soluble in dimethyl sulfoxide , methanol and water.
- InChI
- InChI=1S/C6H4BrNO2/c7-4-1-2-8-5(3-4)6(9)10/h1-3H,(H,9,10)
- InChIKey
- RPHHYRNGCJYQSP-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)=NC=CC(Br)=C1
- CAS DataBase Reference
- 30766-03-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 20/21/22
- Safety Statements
- 24/25-36/37
- HazardClass
- IRRITANT
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B4041
- Product name
- 4-Bromo-2-pyridinecarboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $32
- Updated
- 2025/07/31
- Product number
- B4041
- Product name
- 4-Bromo-2-pyridinecarboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $101
- Updated
- 2025/07/31
- Product number
- B686610
- Product name
- 4-BromopicolinicAcid
- Packaging
- 25g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- B2865-83
- Product name
- 4-Bromopicolinic Acid
- Packaging
- 100mg
- Price
- $403
- Updated
- 2021/12/16
- Product number
- B528
- Product name
- 4-Bromopicolinicacid
- Packaging
- 500g
- Price
- $1921
- Updated
- 2021/12/16
4-Bromopyridine-2-carboxylic acid Chemical Properties,Usage,Production
Chemical Properties
4-Bromopyridine-2-carboxylic acid is fine needles
Uses
4-Bromopyridine-2-carboxylic acid is a useful synthetic intermediate
Uses
4-Bromopicolinic acid is a useful synthetic intermediate. Also used as a intermediate for agrochemical, pharmaceutical and dyestuff field.
Synthesis
22282-99-1
30766-03-1
4.1.12 Synthesis of 5-bromopyridine-2-carboxylic acid (16): In a 250 mL three-necked flask equipped with a stirrer, thermometer, and condenser tube, 100 mL of water and 4-bromo-2-methylpyridine (15) (4.0 g, 23 mmol) were added. After the mixture was stirred and heated to 80 °C, potassium permanganate (KMnO4) (16.6 g, 105 mmol) was added in three batches at 1 h intervals. The reaction mixture was kept stirred at 80 °C for 3-4 hours. After completion of the reaction, the clarified filtrate was obtained by filtration. The pH of the filtrate was adjusted to 4-5 with concentrated hydrochloric acid (HCl), at which time a small amount of white solid was precipitated, which was a small amount of product (16). After filtration, the filtrate was concentrated in vacuum. To the concentrated residue, an appropriate amount of ethanol was added to dissolve the compound (16), at which time a large amount of white solid precipitated, which was removed by filtration. Finally, the filtrate was concentrated in vacuum to give a light yellow solid product (16) (1.70 g, 33% yield).
References
[1] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 13, p. 3228 - 3236
[2] Patent: WO2008/57497, 2008, A2. Location in patent: Page/Page column 292-293
[3] Patent: WO2007/89669, 2007, A2. Location in patent: Page/Page column 204
[4] Patent: WO2008/57469, 2008, A1. Location in patent: Page/Page column 292-293
[5] Patent: WO2008/57468, 2008, A1. Location in patent: Page/Page column 292-293
4-Bromopyridine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromopyridine-2-carboxylic acid Suppliers
- Tel
- 021-69992220 13701886816
- Fax
- 021-69992237
- roleadchem@163.com
- Country
- China
- ProdList
- 4613
- Advantage
- 50
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 5108538618
- Fax
- 86 510 85386988-8017
- suger.wang@chemfuture.com
- Country
- China
- ProdList
- 832
- Advantage
- 65
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2807
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
View Lastest Price from 4-Bromopyridine-2-carboxylic acid manufacturers
- Product
- 4-Bromopyridine-2-carboxylic acid 30766-03-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-05
- Product
- 4-Bromopyridine-2-carboxylic acid 30766-03-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-12
- Product
- 4-Bromopyridine-2-carboxylic acid 30766-03-1
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customise
- Release date
- 2018-08-09