ChemicalBook > CAS DataBase List > Ginsenoside Rh2

Ginsenoside Rh2

Product Name: Ginsenoside Rh2
CAS No.: 78214-33-2
Chemical Name: Ginsenoside Rh2
Synonyms: 20(S)-Rh2;GINSENOSIDE RH2;Ginsenoside Rh2-RM;Ginsenoside Rh2(P);GINSENOSIDE Rh2(SH);Ginsenoside Rh2(AS);Ginsenoside Rh2 ,98%;3β-(β-D-Glucopyranosyl;R-form-Ginsenoside Rh2;Ginsenoside Rh2, 20(S)-
CBNumber: CB3728899
Molecular Formula: C36H62O8
Formula Weight: 622.88
MOL File: 78214-33-2.mol

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Ginsenoside Rh2 Property

Melting point:: 139-144 °C
Boiling point:: 726.4±60.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
pka: 12.91±0.70(Predicted)
form: Solid
color: White
InChIKey: CKUVNOCSBYYHIS-IRFFNABBSA-N
LogP: 5.620 (est)
CAS DataBase Reference: 78214-33-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 24/25
WGK Germany: 3
RTECS: LZ5776539
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 73658
Product name: Ginsenoside Rh2
Purity: analytical standard
Packaging: 10mg
Price: $736
Updated: 2025/07/31

Cayman Chemical

Product number: 23390
Product name: Ginsenoside Rh2
Purity: ≥98%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 23390
Product name: Ginsenoside Rh2
Purity: ≥98%
Packaging: 5mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 23390
Product name: Ginsenoside Rh2
Purity: ≥98%
Packaging: 10mg
Price: $286
Updated: 2024/03/01

Cayman Chemical

Product number: 23390
Product name: Ginsenoside Rh2
Purity: ≥98%
Packaging: 25mg
Price: $651
Updated: 2024/03/01

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Ginsenoside Rh2 Chemical Properties,Usage,Production

Description

Ginsenoside Rh₂ is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC₅₀ = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh₂ decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh₂ also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.

Chemical Properties

White solid

Uses

20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.

Definition

ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.

Biological Activity

Ginsenoside-Rh2, a plant glycosidewith a dammarane skeleton, has been shown to induce apoptosis in a caspase 3,8-dependent manner or the activation of cyclinA-Cdk2 by caspase 3-mediated cleavage of p21(WAF1/CIP1). Also, ginsenoside-Rh2 was shown to inhibit proliferation by inducing the protein expression of p21 and reducing the protein levels of cyclin D, which resulted in the downregulation of cyclin/Cdk complex kinase activity, a reduction in phosphorylation of pRb and the inhibition of E2F release or modulation of MAP kinases in various cancer cells[1].

References

[1] EUN-KYUNG PARK. Antiallergic activity of ginsenoside Rh2.[J]. Biological & pharmaceutical bulletin, 2003, 26 11: 1581-1584. DOI: 10.1248/bpb.26.1581
[2] EUN-KYUNG PARK. Ginsenoside Rh2 reduces ischemic brain injury in rats.[J]. Biological & pharmaceutical bulletin, 2004, 27 3: 433-436. DOI: 10.1248/bpb.27.433
[3] Y KIKUCHI. Inhibition of human ovarian cancer cell proliferation in vitro by ginsenoside Rh2 and adjuvant effects to cisplatin in vivo.[J]. Anti-Cancer Drugs, 1991, 2 1: 63-67. DOI: 10.1097/00001813-199102000-00009
[4] XI-PING TANG. Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells.[J]. World Journal of Gastroenterology, 2013, 19 10: 1582-1592. DOI: 10.3748/wjg.v19.i10.1582
[5] JIA WANG. Ginsenoside Rh2 alleviates tumor-associated depression in a mouse model of colorectal carcinoma.[J]. American journal of translational research, 2016, 8 5: 2189-2195.

Ginsenoside Rh2 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ginsenoside Rh2 manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: Ginsenoside Rh2 78214-33-2
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 99
Supply Ability: 20tons
Release date: 2025-05-27

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Ginsenoside Rh2 78214-33-2
Price: US $100.00-1000.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-10-06

Shanghai Standard Technology Co., Ltd.

Product: Ginsenoside Rh2 78214-33-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-09-27

78214-33-2, Ginsenoside Rh2Related Search:

Escin Ginsenoside Re Ginsenoside Rg1 GINSENOSIDE RE Ginsenoside Rd TRIBULOSIDE Ginseng extract Ginsenoside Rb1 ginsenoside Rh3 Panaxadiol Panaxatriol Ginsenoside Rc GINSENOSIDE RB2 GINSENOSIDE RH1,Ginsenoside Rh1 ,98% ginsenoside Rh(4) Ginsenoside-Rg5 Ginsenoside Rb3 GINSENOSIDE F2

b-D-Glucopyranoside, (3b,12b)-12,20-dihydroxydaMMar-24-en-3-yl

(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside

Ginsenoside Rh2, 20(S)-

(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside

GINSENOSIDE RH2

dihydroxydammar-24-en-3-yl

β-D-Glucopyranoside, (3β,12β)-12,20-

R-form-Ginsenoside Rh2

12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside

3β-(β-D-Glucopyranosyloxy)dammara-24-ene-12β,20-diol

3β-(β-D-Glucopyranosyl

GINSENOSIDE Rh2(SH)

Ginsenoside Rh2 ,98%

20(S)-Rh2

Natural Plant Extracts Ginsenoside Rh2 HPLC 15% 50% 98% 78214-33-2

2-[[12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl

Ginsenoside Rh2 USP/EP/BP

(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Ginsenoside Rk1&Rh2&Rg3

GINSENOSIDE Rh2 (S-FORM)(AS) 25mg

Ginsenoside Rh2-RM

Ginsenoside Rh2(AS)

Ginsenoside Rh2(P)

10% Ginseng extract inclusion complex

20(S)-Ginsenoside Rh2, Active component of red ginseng

Ginsenoside Rh2, 10 mM in DMSO

78214-33-2

C36H62O8

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Inhibitors

Ginsenoside series

78214-33-2